ORAI1 (NM_032790) Human Untagged Clone

CAT#: SC321019

ORAI1 (untagged)-Human ORAI calcium release-activated calcium modulator 1 (ORAI1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ORAI1
• Synonyms: CRACM1; IMD9; ORAT1; TAM2; TMEM142A
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_032790.2 GCCGCCCGGGGGCTTTTGCCAGCGGCGCCGCGGGCCTGCGTGCTGGGGCAGCGGGCACTT
  CTTCGACCTCGTCCTCCTCGTCCTGTGCGGCCGGCCGGGTGAGGCCGGGCCCGCGTAGGG
  GGCAGTCGGCGGCTGCCTCCGGCGGAGGTGCCTCGCGGCGCCCGGGCCGGCCCGCGCCTC
  GGCGGCGTGCTCCATGCATCCGGAGCCCGCCCCGCCCCCGAGCCGCAGCAGTCCCGAGCT
  TCCCCCAAGCGGCGGCAGCACCACCAGCGGCAGCCGCCGGAGCCGCCGCCGCAGCGGGGA
  CGGGGAGCCCCCGGGGGCCCCGCCACCGCCGCCGTCCGCCGTCACCTACCCGGACTGGAT
  CGGCCAGAGTTACTCCGAGGTGATGAGCCTCAACGAGCACTCCATGCAGGCGCTGTCCTG
  GCGCAAGCTCTACTTGAGCCGCGCCAAGCTTAAAGCCTCCAGCCGGACCTCGGCTCTGCT
  CTCCGGCTTCGCCATGGTGGCAATGGTGGAGGTGCAGCTGGACGCTGACCACGACTACCC
  ACCGGGGCTGCTCATCGCCTTCAGTGCCTGCACCACAGTGCTGGTGGCTGTGCACCTGTT
  TGCGCTCATGATCAGCACCTGCATCCTGCCCAACATCGAGGCGGTGAGCAACGTGCACAA
  TCTCAACTCGGTCAAGGAGTCCCCCCATGAGCGCATGCACCGCCACATCGAGCTGGCCTG
  GGCCTTCTCCACCGTCATCGGCACGCTGCTCTTCCTAGCTGAGGTGGTGCTGCTCTGCTG
  GGTCAAGTTCTTGCCCCTCAAGAAGCAGCCAGGCCAGCCAAGGCCCACCAGCAAGCCCCC
  CGCCAGTGGCGCAGCAGCCAACGTCAGCACCAGCGGCATCACCCCGGGCCAGGCAGCTGC
  CATCGCCTCGACCACCATCATGGTGCCCTTCGGCCTGATCTTTATCGTCTTCGCCGTCCA
  CTTCTACCGCTCACTGGTTAGCCATAAGACCGACCGACAGTTCCAGGAGCTCAACGAGCT
  GGCGGAGTTTGCCCGCTTACAGGACCAGCTGGACCACAGAGGGGACCACCCCCTGACGCC
  CGGCAGCCACTATGCCTAGGCCCATGTGGTCTGGGCCCTTCCAGTGCTTTGGCCTTACGC
  CCTTCCCCTTGACCTTGTCCTGCCCCAGCCTCACGGACAGCCTGCGCAGGGGGCTGGGCT
  TCAGCAAGGGGCAGAGCGTGGAGGGAAGAGGATTTTTATAAGAGAAATTTCTGCACTTTG
  AAACTGTCCTCTAAGAGAATAAGCATTTCCTGTTCTTCCAGCTCCAGGTCCACCTCCTGT
  TGGGAGGCGGTGGGGGGCCAAAGTGGGGCCACACACTCGCTGTGTCCCCTCTCCTCCCCT
  GTGCCAGTGCCACCTGGGTGCCTCCTCCTGTCCTGTCCGTCTCAACCTCCCTCCCGTCCA
  GCATTGAGTGTGTACATGTGTGTGTGACACATAAATATACTCATAAGGACAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032790.2 unedited
  GACCATTGTATACGACTACTATAGGGCGGCAGGCAAATCGGCACGAGGGCCGCCCGGGGG
  CTTTTGCCAGCGGCGCCGCGGGCCTGCGTGCTGGGGCAGCGGGCACTTCTTCGACCTCGT
  CCTCCTCGTCCTGTGCGGCCGGCCGGGTGAGGCCGGGCCCGCGTAGGGGGCAGTCGGCGG
  CTGCCTCCGGCGGAGGTGCCTCGCGGCGCCCGGGCCGGCCCGCGCCTCGGCGGCGTGCTC
  CATGCATCCGGAGCCCGCCCCGCCCCCGAGCCGCAGCAGTCCCGAGCTTCCCCCAAGCGG
  CGGCAGCACCACCAGCGGCAGCCGCCTTTTTTTTTTTTCGCAGCGGGGACGGGGAGCCCT
  CGGGGGCCCCGCCACCGCCGCCGTCCGCCGTCACCTACCCGGACTGGATCGGCCAGAGTT
  ACTCCGAGGTGATGAGCCTCAACGAGCACTCCATGCAGGCGCTGTCCTGGCGCAAGCTCT
  ACTTGAGCCGCGCCAAGCTTAAAGCCTCCAGCCGGACCTCGGCTCTGCTCTCCGGCTTCG
  CCATGGTGGCAATGGTGGAGGTGCAGCTGGACGCTGACCACGACTACCCACCGGGGCTGC
  TCATCGCCTTCAGTGCCTGCACCACAGTGCTGGTGGCTGTGCACCTGTTTGCGCTCATGA
  TCAGCACCTGCATCCTGCCCAACATCGAGCGGTGAGCAACGTGCACAATCTCAACTCGGT
  CAAGGAGTCCCCCCATGAGCGCATGCACCGCACATCGAGCTGGCCTGGGCCTTCTCCACC
  GTCATCGGCACGCTGCTCTTCCTACTGAGTGTGCTGCTCTGCTGGGTCAAGTTCTTGCCC
  CTCAGAAGCACCAGCCAGCCAAGCCCAACAGCAAGCCCCCCGCAGTTGGCCGCAGCAGCC
  AACGTCAGCACCAGCGCATACCCCGGTCAGCAGCTTGCATCGGCTCGGACCACATTAATG
  GGTGACCCT
• Restriction Sites: Please inquire
• ACCN: NM_032790
• ORF Size: 906 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_032790.2, NP_116179.2
• RefSeq Size: 1497
• RefSeq ORF: 906
• Locus ID: 84876
• Protein Families: Transmembrane
• Gene Summary: The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]