PRC1 (NM_003981) Human Untagged Clone

CAT#: SC321569

PRC1 (untagged)-Human protein regulator of cytokinesis 1 (PRC1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PRC1
• Synonyms: ASE1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003981.2 GCTACGCGGAGTGACATCGCCGGTGTTTGCGGGTGGTTGTTGCTCTCGGGGCCGTGTGGA
  GTAGGTCTGGACCTGGACTCACGGCTGCTTGGAGCGTCCGCCATGAGGAGAAGTGAGGTG
  CTGGCGGAGGAGTCCATAGTATGTCTGCAGAAAGCCCTAAATCACCTTCGGGAAATATGG
  GAGCTAATTGGGATTCCAGAGGACCAGCGGTTACAAAGAACTGAGGTGGTAAAGAAGCAT
  ATCAAGGAACTCCTGGATATGATGATTGCTGAAGAGGAAAGCCTGAAGGAAAGACTCATC
  AAAAGCATATCCGTCTGTCAGAAAGAGCTGAACACTCTGTGCAGCGAGTTACATGTTGAG
  CCATTTCAGGAAGAAGGAGAGACAACCATCTTGCAACTAGAAAAAGATTTGCGCACCCAA
  GTGGAATTGATGCGAAAACAGAAAAAGGAGAGAAAACAGGAACTGAAGCTACTTCAAGAG
  CAAGATCAAGAACTGTGCGAAATTCTTTGTATGCCCCACTATGATATTGACAGTGCCTCA
  GTGCCCAGCTTAGAAGAGCTGAACCAGTTCAGGCAACATGTGACAACTTTGAGGGAAACA
  AAGGCTTCTAGGCGTGAGGAGTTTGTCAGTATAAAGAGACAGATCATACTGTGTATGGAA
  GAATTAGACCACACCCCAGACACAAGCTTTGAAAGAGATGTGGTGTGTGAAGACGAAGAT
  GCCTTTTGTTTGTCTTTGGAGAATATTGCAACACTACAAAAGTTGCTACGGCAGCTGGAA
  ATGCAGAAATCACAAAATGAAGCAGTGTGTGAGGGGCTGCGTACTCAAATCCGAGAGCTC
  TGGGACAGGTTGCAAATACCTGAAGAAGAAAGAGAAGCTGTGGCCACCATTATGTCTGGG
  TCAAAGGCCAAGGTCCGGAAAGCGCTGCAATTAGAAGTGGATCGGTTGGAAGAACTGAAA
  ATGCAAAACATGAAGAAAGTGATTGAGGCAATTCGAGTGGAGCTGGTTCAGTACTGGGAC
  CAGTGCTTTTATAGCCAGGAGCAGAGACAAGCTTTTGCCCCTTTCTGTGCTGAGGACTAC
  ACAGAAAGTCTGCTCCAGCTCCACGATGCTGAGATTGTGCGGTTAAAAAACTACTATGAA
  GTTCACAAGGAACTCTTTGAAGGTGTCCAGAAGTGGGAAGAAACCTGGAGGCTTTTCTTA
  GAGTTTGAGAGAAAAGCTTCAGATCCAAATCGATTTACAAACCGAGGAGGAAATCTTCTA
  AAAGAAGAAAAACAACGAGCCAAGCTCCAGAAAATGCTGCCCAAGCTGGAAGAAGAGTTG
  AAGGCACGAATTGAATTGTGGGAACAGGAACATTCAAAGGCATTTATGGTGAATGGGCAG
  AAATTCATGGAGTATGTGGCAGAACAATGGGAGATGCATCGATTGGAGAAAGAGAGAGCC
  AAGCAGGAAAGACAACTGAAGAACAAAAAACAGACAGAGACAGAGATGCTGTATGGCAGC
  GCTCCTCGAACACCTAGCAAGCGGCGAGGACTGGCTCCCAATACACCGGGCAAAGCACGT
  AAGCTGAACACTACCACCATGTCCAATGCTACGGCCAATAGTAGCATTCGGCCTATCTTT
  GGAGGGACAGTCTACCACTCCCCCGTGTCTCGACTTCCTCCTTCTGGCAGCAAGCCAGTC
  GCTGCTTCCACCTGTTCAGGGAAGAAAACACCCCGTACTGGCAGGCATGGAGCCAACAAG
  GAGAACCTGGAGCTCAACGGCAGCATCCTGAGTGGTGGGTACCCTGGCTCGGCCCCCCTC
  CAGCGCAACTTCAGCATTAATTCTGTTGCCAGCACCTATTCTGAGTTTGCGAAGGATCCG
  TCCCTCTCTGACAGTTCCACTGTTGGGCTTCAGCGAGAACTTTCAAAGGCTTCCAAATCT
  GATGCTACTTCTGGAATCCTCAATTCAACCAACATCCAGTCCTGAGAAGCCCTGATCAGT
  CAACCAGCTGTGGCTTCCTGTGCCTAGACTGGACCTAATTATATGGGGGTGACTTTAGTT
  TTTCTTCAGCTTAGGCGTGCTTGAAACCTTGGCCAGGTTCCATGACCATGGGCCTAACTT
  AAAGATGTGAATGAGTGTTACAGTTGAAAGCCCATCATAGGTTTAGTGGTCCTAGGAGAC
  TTGGTTTTGACTTATATACATGAAAAGTTTATGGCAAGAAGTGCAAATTTTAGCATATGG
  GGCCTGACTTCTCTACCACATAATTCTACTTGCTGAAGCATGATCAAAGCTTGTTTTATT
  TCACCACTGTAGGAAAATGATTGACTATGCCCATCCCTGGGGGTAATTTTGGCATGTATA
  CCTGTAACTAGTAATTAACATCTTTTTTGTTTAGGCATGTTCAATTAATGCTGTAGCTAT
  CATAGCTTTGCTCTTACCTGAAGCCTTGTCCCCACCACACAGGACAGCCTTCCTCCTGAA
  GAGAATGTCTTTGTGTGTCCGAAGTTGAGATGGCCTGCCCTACTGCCAAAGAGGTGACAG
  GAAGGCTGGGAGCAGCTTTGTTAAATTGTGTTCAGTTCTGTTACACAGTGCATTGCCCTT
  TGTTGGGGGTATGCATGTATGAACACACATGCTTGTCGGAACGCTTTCTCGGCGTTTGTC
  CCTTGGCTCTCATCTCCCCCATTCCTGTGCCTACTTTGCCTGAGTTCTTCTACCCCCGCA
  GTTGCCAGCCACATTGGGAGTCTGTTTGTTCCAGTGGGTTGAGCTGTCTTTGTCGTGGAG
  ATCTGGAACTTTGCACATGTCACTACTGGGGAGGTGTTCCTGCTCTAGCTTCCACGATGA
  GGCGCCCTCTTTACCTATCCTCTCAATCACTACTCTTCTTGAAGCACTATTATTTATTCT
  TCCGCTGTCTGCCTGCAGCAGTACTACTGTCAACATAGTGTAAATGGTTCTCAAAAGCTT
  ACCAGTGTGGACTTGGTGTTAGCCACGCTGTTTACTCATACAGTACGTGTCCTGTTTTTA
  AAATATACAATTATTCTTAAAAATAAATTAAAATCTGTATACTTACATTTCAAAAAAAAA
  AAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003981.2 unedited
  GACCTTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGCTACGCGGAGT
  GACATCGCCGGTGTTTGCGGGTGGTTGTTGCTCTCGGGGCCGTGTGGAGTAGGTCTGGAC
  CTGGACTCACGGCTGCTTGGAGCGTCCGCCATGAGGAGAAGTGAGGTGCTGGCGGAGGAG
  TCCATAGTATGTCTGCAGAAAGCCCTAAATCACCTTCGGGAAATATGGGAGCTAATTGGG
  ATTCCAGAGGACCAGCGGTTACAAAGAACTGAGGTGGTAAAGAAGCATATCAAGGAACTC
  CTGGATATGATGATTGCTGAAGAGGAAAGCCTGAAGGAAAGACTCATCAAAAGCATATCC
  GTCTGTCAGAAAGAGCTGAACACTCTGTGCAGCGAGTTACATGTTGAGCCATTTCAGGAA
  GAAGGAGAGACAACCATCTTGCAACTAGAAAAAGATTTGCGCACCCAAGTGGAATTGATG
  CGAAAACAGAAAAAGGAGAGAAAACAGGAACTGAAGCTACTTCAAGAGCAAGATCAAGAA
  CTGTGCGAAATTCTTTGTATGCCCCACTATGATATTGACAGTGCCTCAGTGCCCAGCTTA
  GAAGAGCTGAACCAGTTCAGCAACATGTGACAACTTTGAGGGAAACAAAGGCTTCTAGGC
  GTGAGGAGTTTGTCAGTATAAAGAGACAGATCATACTGTGTATGGGAAGATTTAGACCAC
  ACCCCAGACACAAGCTTTGAAAGAGATGTGGTGTGTGAAGACGAGATGCCTTTTTGTTTT
  GTCTTTGGAGAATATTGCAACACTACAAAAAGTGCTACGCAGCTGGAAATGCAGAAATCA
  CAATGAGCAGTGGTGGTGGAGGGGCTGCGTACTCAATCGAGAGCCTCTGGACAGTTGCAA
  TACTGGAGAGAAGAGAAAGCTTGCACATTATGTTCTGTTCAGCAAGTTCGTAAGGCGCTT
  GCTATTGGAG
• Restriction Sites: Please inquire
• ACCN: NM_003981
• ORF Size: 1863 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003981.2, NP_003972.1
• RefSeq Size: 3128
• RefSeq ORF: 1863
• Locus ID: 9055
• Domains: MAP65_ASE1
• Gene Summary: This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).