NDRG1 (NM_006096) Human Untagged Clone

CAT#: SC321592

NDRG1 (untagged)-Human N-myc downstream regulated 1 (NDRG1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NDRG1
• Synonyms: CAP43; CMT4D; DRG-1; DRG1; GC4; HMSNL; NDR1; NMSL; PROXY1; RIT42; RTP; TARG1; TDD5
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006096.2 CTGGTGCTGAAGCTCGTCAGTTCACCATCCGCCCTCGGCTTCCGCGGGGCGCTGGGCCGC
  CAGCCTCGGCACCGTCCTTTCCTTTCTCCCTCGCGTTAGGCAGGTGACAGCAGGGACATG
  TCTCGGGAGATGCAGGATGTAGACCTCGCTGAGGTGAAGCCTTTGGTGGAGAAAGGGGAG
  ACCATCACCGGCCTCCTGCAAGAGTTTGATGTCCAGGAGCAGGACATCGAGACTTTACAT
  GGCTCTGTTCACGTCACGCTGTGTGGGACTCCCAAGGGAAACCGGCCTGTCATCCTCACC
  TACCATGACATCGGCATGAACCACAAAACCTGCTACAACCCCCTCTTCAACTACGAGGAC
  ATGCAGGAGATCACCCAGCACTTTGCCGTCTGCCACGTGGACGCCCCTGGCCAGCAGGAC
  GGCGCAGCCTCCTTCCCCGCAGGGTACATGTACCCCTCCATGGATCAGCTGGCTGAAATG
  CTTCCTGGAGTCCTTCAACAGTTTGGGCTGAAAAGCATTATTGGCATGGGAACAGGAGCA
  GGCGCCTACATCCTAACTCGATTTGCTCTAAACAACCCTGAGATGGTGGAGGGCCTTGTC
  CTTATCAACGTGAACCCTTGTGCGGAAGGCTGGATGGACTGGGCCGCCTCCAAGATCTCA
  GGATGGACCCAAGCTCTGCCGGACATGGTGGTGTCCCACCTTTTTGGGAAGGAAGAAATG
  CAGAGTAACGTGGAAGTGGTCCACACCTACCGCCAGCACATTGTGAATGACATGAACCCC
  GGCAACCTGCACCTGTTCATCAATGCCTACAACAGCCGGCGCGACCTGGAGATTGAGCGA
  CCAATGCCGGGAACCCACACAGTCACCCTGCAGTGCCCTGCTCTGTTGGTGGTTGGGGAC
  AGCTCGCCTGCAGTGGATGCCGTGGTGGAGTGCAACTCAAAATTGGACCCAACAAAGACC
  ACTCTCCTCAAGATGGCGGACTGTGGCGGCCTCCCGCAGATCTCCCAGCCGGCCAAGCTC
  GCTGAGGCCTTCAAGTACTTCGTGCAGGGCATGGGATACATGCCCTCGGCTAGCATGACC
  CGCCTGATGCGGTCCCGCACAGCCTCTGGTTCCAGCGTCACTTCTCTGGATGGCACCCGC
  AGCCGCTCCCACACCAGCGAGGGCACCCGAAGCCGCTCCCACACCAGCGAGGGCACCCGC
  AGCCGCTCGCACACCAGCGAGGGGGCCCACCTGGACATCACCCCCAACTCGGGTGCTGCT
  GGGAACAGCGCCGGGCCCAAGTCCATGGAGGTCTCCTGCTAGGCGGCCTGCCCAGCTGCC
  GCCCCCGGACTCTGATCTCTGTAGTGGCCCCCTCCTCCCCGGCCCCTTTTCGCCCCCTGC
  CTGCCATACTGCGCCTAACTCGGTATTAATCCAAAGCTTATTTTGTAAGAGTGAGCTCTG
  GTGGAGACAAATGAGGTCTATTACGTGGGTGCCCTCTCCAAAGGCGGGGTGGCGGTGGAC
  CAAAGGAAGGAAGCAAGCATCTCCGCATCGCATCCTCTTCCATTAACCAGTGGCCGGTTG
  CCACTCTCCTCCCCTCCCTCAGAGACACCAAACTGCCAAAAACAAGACGCGTAGCAGCAC
  ACACTTCACAAAGCCAAGCCTAGGCCGCCCTGAGCATCCTGGTTCAAACGGGTGCCTGGT
  CAGAAGGCCAGCCGCCCACTTCCCGTTTCCTCTTTAACTGAGGAGAAGCTGATCCAGTTT
  CCGGAAACAAAATCCTTTTCTCATTTGGGGAGGGGGGTAATAGTGACATGCAGGCACCTC
  TTTTAAACAGGCAAAACAGGAAGGGGGAAAAGGTGGGATTCATGTCGAGGCTAGAGGCAT
  TTGGAACAACAAATCTACGTAGTTAACTTGAAGAAACCGATTTTTAAAGTTGGTGCATCT
  AGAAAGCTTTGAATGCAGAAGCAAACAAGCTTGATTTTTCTAGCATCCTCTTAATGTGCA
  GCAAAAGCAGGCAACAAAATCTCCTGGCTTTACAGACAAAAATATTTCAGCAAACGTTGG
  GCATCATGGTTTTTGAAGGCTTTAGTTCTGCTTTCTGCCTCTCCTCCACAGCCCCAACCT
  CCCACCCCTGATACATGAGCCAGTGATTATTCTTGTTCAGGGAGAAGATCATTTAGATTT
  GTTTTGCATTCCTTAGAATGGAGGGCAACATTCCACAGCTGCCCTGGCTGTGATGAGTGT
  CCTTGCAGGGGCCGGAGTAGGAGCACTGGGGTGGGGGCGGAATTGGGGTTACTCGATGTA
  AGGGATTCCTTGTTGTTGTGTTGAGATCCAGTGCAGTTGTGATTTCTGTGGATCCCAGCT
  TGGTTCCAGGAATTTTGTGTGATTGGCTTAAATCCAGTTTTCAATCTTCGACAGCTGGGC
  TGGAACGTGAACTCAGTAGCTGAACCTGTCTGACCCGGTCACGTTCTTGGATCCTCAGAA
  CTCTTGCTCTTGTCGGGGTGGGGGTGGGAACTCACGTGGGGAGCGGTGGCTGAGAAAATG
  TAAGGATTCTGGAATACATATTCCATGGGACTTTCCTTCCCTCTCCTGCTTCCTCTTTTC
  CTGCTCCCTAACCTTTCGCCGAATGGGGCAGCACCACTGACGTTTCTGGGCGGCCAGTGC
  GGCTGCCAGGTTCCTGTACTACTGCCTTGTACTTTTCATTTTGGCTCACCGTGGATTTTC
  TCATAGGAAGTTTGGTCAGAGTGAATTGAATATTGTAAGTCAGCCACTGGGACCCGAGGA
  TTTCTGGGACCCCGCAGTTGGGAGGAGGAAGTAGTCCAGCCTTCCAGGTGGCGTGAGAGG
  CAATGACTCGTTACCTGCCGCCCATCACCTTGGAGGCCTTCCCTGGCCTTGAGTAGAAAA
  GTCGGGGATCGGGGCAAGAGAGGCTGAGTACGGATGGGAAACTATTGTGCACAAGTCTTT
  CCAGAGGAGTTTCTTAATGAGATATTTGTATTTATTTCCAGACCAATAAATTTGTAACTT
  TGCAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006096.2 unedited
  GACATTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGCTGGTGCTGAAG
  CTCGTCAGTTCACCATCCGCCCTCGGCTTCCGCGGGGCGCTGGGCCGCCAGCCTCGGCAC
  CGTCCTTTCCTTTCTCCCTCGCGTTAGGCAGGTGACAGCAGGGACATGTCTCGGGAGATG
  CAGGATGTAGACCTCGCTGAGGTGAAGCCTTTGGTGGAGAAAGGGGAGACCATCACCGGC
  CTCCTGCAAGAGTTTGATGTCCAGGAGCAGGACATCGAGACTTTACATGGCTCTGTTCAC
  GTCACGCTGTGTGGGACTCCCATGGGAAACCGGCCTGTCATCCTCACCTACCATGACATC
  GGCATGAACCACAAAACCTGCTACAACCCCCTCTTCAACTACGAGGACATGCAGGAGATC
  ACCCAGCACTTTGCCGTCTGCCACGTGGACGCCCCTGGCCAGCAGGACGGCGCAGCCTCC
  TTCCCCGCAGGGTACATGTACCCCTCCATGGATCAGCTGGCTGAAATGCTTCCTGGAGTC
  CTTCAACAGTTTGGGCTGAAAAGCATTATTGGCATGGGAACAGGAGCAGGCGCCTACATC
  CTAACTCGATTTGCTCTAAACAACCCTGAGATGGTGGAGGGCCTTGTCCTTATCAACGTG
  AACCCTTGTGCGGAAGGCTGGATGGACTGGGCCGCCTCCAAGATCTCAGGATGGACCCAA
  GCTCTGCCCGGACATGGTGGTGTCCCACCTTTTTGGGAGGAGAAATGCAGAGTAACGTGG
  AAGTGGTCCACCACCTACCGCCAGCACCATTGTGATGAACATGAACCCCGGCAACCTGCA
  CCTGGTCATCATGCTACAACAGCGGGCGGCGGACCTGGAGATTGAAGCGACCATGCGGGA
  CCCACCACAGGTACCTGCATTGCTTGGCTCTTGTGGTGGTGGGCAACAGCTCGCCTTCGC
  AATTGATGCGTGGTGTGGAGGTGCA
• Restriction Sites: Please inquire
• ACCN: NM_006096
• ORF Size: 1185 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006096.2, NP_006087.2
• RefSeq Size: 3074
• RefSeq ORF: 1185
• Locus ID: 10397
• Domains: Ndr
• Gene Summary: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR. Variants 1 and 2 encode the same isoform (1).