RNF125 (NM_017831) Human Untagged Clone

CAT#: SC321663

RNF125 (untagged)-Human ring finger protein 125 (RNF125)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RNF125
• Synonyms: TNORS; TRAC-1; TRAC1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_017831.3 GAGAGGCACAGCGATGGGCTCCGTGCTGAGCACCGACAGCGGCAAATCGGCGCCCGCCTC
  TGCCACCGCGCGGGCCCTGGAGCGCAGGAGGGACCCGGAGTTGCCCGTCACGTCCTTCGA
  CTGCGCCGTGTGCCTTGAGGTGTTACACCAGCCTGTCCGGACCCGCTGTGGCCACGTATT
  CTGCCGTTCCTGTATTGCTACCAGTCTAAAGAACAACAAGTGGACCTGTCCTTATTGCCG
  GGCATATCTTCCTTCAGAAGGAGTTCCAGCAACTGATGTAGCCAAAAGAATGAAATCAGA
  GTATAAGAACTGCGCTGAGTGTGACATAGTTCTTTACCTCAGTGAAATGAGGGCACATAT
  TCGGACTTGTCAGAAGTACATAGATAAGTATGGACCACTACAAGAACTTGAGGAGACAGC
  AGCAAGGTGTGTATGTCCCTTTTGTCAGAGGGAACTGTATGAAGACAGCTTGCTGGATCA
  TTGTATTACTCATCACAGATCGGAACGGAGGCCTGTGTTCTGTCCACTTTGCCGTTTAAT
  ACCCGATGAGAATCCAAGCAGCTTCAGTGGCAGTTTAATAAGACATCTGCAAGTTAGTCA
  CACTTTGTTTTATGATGATTTCATAGATTTTAATATAATTGAGGAAGCTCTTATCCGAAG
  AGTCTTAGACCGGTCACTTCTTGAATATGTGAATCACTCGAACACAGCATAATTTTATTA
  AAACGAAGGGAAAAGGGACCACTGAATTGCACCATTTAAGATGCTGCTTGAACAAATGGG
  AGGGAAGTTGTCAATGATTGATGGGCAAAAATGTACAACACAGTTATGTGTTTGTCCATG
  TTTATTGTTATAGTGCATTTAAAAACTGCTTTAATTTTAATGGTTTAAATCTGTTTTACA
  TCCTTGAGATTCTTACACATCTAACAACAAAAAAAATTATCTACATCAGTCATTGTTACA
  TGGAAAAGACAGGTGGTAGGCAAGTAGGTGGAGGATCTCGGTTTGCAAATTAGATAATAC
  TCTGTGTATAATGCTACATATCAATAACTACCATCATGGTTAGGCACGATAACTAATCTT
  TGTTCTGTGTAAAAAAATATGGAGAGTGAAACAAAGTGCAGACATTCAAAGAAATAAGAA
  ATCTGCTCCAATGCTCTTGTTCTAATCTCTAATAGGTTAACGTTAATAATCTTGTATGGG
  AGTTGGAAAGGAAAATTTTGGAAGTCAAGAAAGTCCATTTAGGCCGGACGCGGTGGCTTA
  CGCTTGTAATCCCAGCACTTTGGGAGGCTGAAGCAGGCGGATCACAGGGTCAGGAGTTCG
  AGACCAGCCTGGCCAACACTGGTCTCTGTGAAACTCCGTCTCTACTAAGAATACAAAAAT
  TAGCTGGACGTGTTGGCGGGCATCTGTAATACCAGCTACTTGGGAGGCTGAGGCAGAAGA
  ATCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCAGTACACTCCAG
  CCTGGGTAACAGAGCTAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017831.3 unedited
  TACCTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGGAGAGGCACAGCGATGGGCTCCGTGCT
  GAGCACCGACAGCGGCAAATCGGCGCCCGCCTCTGCCACCGCGCGGGCCCTGGAGCGCAG
  GAGGGACCCGGAGTTGCCCGTCACGTCCTTCGACTGCGCCGTGTGCCTTGAGGTGTTACA
  CCAGCCTGTCCGGACCCGCTGTGGCCACGTATTCTGCCGTTCCTGTATTGCTACCAGTCT
  AAAGAACAACAAGTGGACCTGTCCTTATTGCCGGGCATATCTTCCTTCAGAAGGAGTTCC
  AGCAACTGATGTAGCCAAAAGAATGAAATCAGAGTATAAGAACTGCGCTGAGTGTGACAC
  CCTGGTTTGCCTCAGTGAAATGAGGGCACATATTCGGACTTGTCAGAAGTACATAGATAA
  GTATGGACCACTACAAGAACTTGAGGAGACAGCAGCAAGGTGTGTATGTCCCTTTTGTCA
  GAGGGAACTGTATGAAGACAGCTTGCTGGATCATTGTATTACTCATCACAGATCGGAACG
  GAGGCCTGTGTTCTGTCCACTTTGCCGTTTAATACCCGATGAGAATCCAAGCAGCTTCAG
  TGGCAGTTTAATAAGACATCTGCAAGTTAGTCACACTTTGTTTTATGATGATTTCATAGA
  TTTTAATATAATTGAGGAAGCTCTTATCCGAGGAGTCTTAGACCGGTCACTTCTTGGAAT
  ATGGTGAATCACTCGACACCACAATAATTTTATTAAAACGAAGGAAAAGGGACACTGATG
  CACCATTTAGATGCTGCTGAACAAATGGGAGGGAAGTTGTCAATGATTGGATGGGCAAAA
  TGTTACCAACACACAGGTATA
• Restriction Sites: Please inquire
• ACCN: NM_017831
• ORF Size: 699 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017831.3, NP_060301.2
• RefSeq Size: 5888
• RefSeq ORF: 699
• Locus ID: 54941
• Domains: RING
• Protein Families: Druggable Genome
• Protein Pathways: RIG-I-like receptor signaling pathway
• Gene Summary: This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012]