HIST1H2BK (NM_080593) Human Untagged Clone

CAT#: SC322213

HIST1H2BK (untagged)-Human histone cluster 1, H2bk (HIST1H2BK)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HIST1H2BK
• Synonyms: H2B/S; H2BFAiii; H2BFT; H2BK
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322213 CTCGATCTGCTGCTCGTCTCAGGCTCGTAGTTCGCCTTCAACATGCCGGAACCAGCGAAG
  TCCGCTCCCGCGCCCAAGAAGGGCTCGAAGAAAGCCGTGACTAAGGCGCAGAAGAAGGAC
  GGCAAGAAGCGCAAGCGCAGCCGCAAGGAGAGCTACTCCGTATACGTGTACAAGGTGCTG
  AAGCAGGTCCACCCCGACACCGGCATCTCCTCTAAGGCCATGGGAATCATGAACTCCTTC
  GTCAACGACATCTTCGAACGCATCGCGGGTGAGGCTTCCCGCCTGGCGCATTACAACAAG
  CGCTCGACCATCACCTCCAGGGAGATCCAGACGGCCGTGCGCCTGCTGCTGCCCGGGGAG
  TTGGCCAAGCACGCCGTGTCCGAGGGCACCAAGGCCGTCACCAAGTACACCAGCGCTAAG
  TAAACTTGCCAAGGAGGGACTTTCTCTGGAATTTCCTGATATGACCAAGAAAGCTTCTTA
  TCAAAAGAAGCACAATTGCCTTCGGTTACCTCATTATCTACTGCAGAAAAGAAGACGAGA
  ATGCAACCATACCTAGATGGACTTTTCCACAAGCTAAAGCTGGCCTCTTGATCTCATTCA
  GATTCCAAAGAGAATCATTTACAAGTTAATTTCTGTCTCCTTGGTCCATTCCTTCTCTCT
  AATAATCATTTACTGTTCCTCAAAGAATTGTCTACATTACCCATCTCCTCTTTTGCCTCT
  GAGAAAGAGTATATAAGCTTCTGTACCCCACTGGGGGGTTGGGGTAATATTCTGTGGTCC
  TCAGCCCTGTACCTTAATAAATTTGTATGCCTTTTCTCTTAAAAAAAAAAAAAAAAAAAA
  AAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322213 unedited
  TGCCATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGCTCGATCTGCTGCTCGTCTCAGGCTCG
  TAGTTCGCCTTCAACATGCCGGAACCAGCGAAGTCCGCTCCCGCGCCCAAGAAGGGCTCG
  AAGAAAGCCGTGACTAAGGCGCAGAAGAAGGACGGCAAGAAGCGCAAGCGCAGCCGCAAG
  GAGAGCTACTCCGTATACGTGTACAAGGTGCTGAAGCAGGTCCACCCCGACACCGGCATC
  TCCTCTAAGGCCATGGGAATCATGAACTCCTTCGTCAACGACATCTTCGAACGCATCGCG
  GGTGAGGCTTCCCGCCTGGCGCATTACAACAAGCGCTCGACCATCACCTCCAGGGAGATC
  CAGACGGCCGTGCGCCTGCTGCTGCCCGGGGAGTTGGCCAAGCACGCCGTGTCCGAGGGC
  ACCAAGGCCGTCACCAAGTACACCAGCGCTAAGTAAACTTGCCAAGGAGGGACTTTCTCT
  GGAATTTCCTGATATGACCAAGAAAGCTTCTTATCAAAAGAAGCACAATTGCCTTCGGTT
  ACCTCATTATCTACTGCAGAAAAGAAGACGAGAATGCAACCATACCTAGATGGACTTTTC
  CACAAGCTAAAGCTGGCCTCTTGATCTCATTCAGATTCCAAAGAGAATCATTTACAAGTT
  AATTTCTGTCTCCTTGGTCCATTCCTTCTCTCTAATAATCATTTACTGTTCCTCAAAGAA
  TTGTCTACATTACCCATCTCCTCTTTTGCCTCTGAGAAGAGTATATAGCTCCTGTACCCA
  CTGGGGGTGGGTATATCTGTGGGTCCTCAGCCCTGTACCTAATAAATGGATGCGTTTCTC
  TTAAAACAAAAATATAAAAAGAGGCCAGCCAGCACTCTCAGGTTTTAAAACGTCG
• Restriction Sites: Please inquire
• ACCN: NM_080593
• ORF Size: 381 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_080593.1, NP_542160.1
• RefSeq Size: 820
• RefSeq ORF: 381
• Locus ID: 85236
• Protein Pathways: Systemic lupus erythematosus
• Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family. The protein encoded is an antimicrobial protein with antibacterial and antifungal activity. Two transcripts that encode the same protein have been identified for this gene, which is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]
  Transcript Variant: This variant (2) differs from variant 1 in its 3' UTR which contains a polyA signal and site. Variants 1 and 2 encode the same protein.