KCNIP1 (NM_014592) Human Untagged Clone

CAT#: SC322651

KCNIP1 (untagged)-Human Kv channel interacting protein 1 (KCNIP1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNIP1
• Synonyms: KCHIP1; VABP
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322651 AGGCTTCAGGGCACCGTCCTCGGCCCTGGGCGAGGGAACCGCCGGGCCGGGTCCTCGCGC
  GGGGAAGCGGTTCCGAAGGCTCGCGGGGAGCGGCTAGCCCTGAGTCCCTGCATGTGCGGG
  GCTGAAGAAGGAAGCCAGAAGCCTCCTAGCCTCGCCTCCACGCTTGCTGAATACCAAGCT
  GCAGGCGAGCTGCCGGGCGCTTTTCTCTCCTCCAATTCAGAGTAGACAAACCACGGGGAT
  TTCTTTCCAGGGTAGGGGAGGGGCCGGGCCCGGGGTCCCAACTCGCACTCAAGTCTTCGC
  TGCCATGGGGGCCGTCATGGGCACCTTCTCATCTCTGCAAACCAAACAAAGGCGACCCTC
  GAAAGATAAGATTGAAGATGAGCTGGAGATGACCATGGTTTGCCATCGGCCCGAGGGACT
  GGAGCAGCTCGAGGCCCAGACCAACTTCACCAAGAGGGAGCTGCAGGTCCTTTATCGAGG
  CTTCAAAAATGAGTGCCCCAGTGGTGTGGTCAACGAAGACACATTCAAGCAGATCTATGC
  TCAGTTTTTCCCTCATGGAGATGCCAGCACGTATGCCCATTACCTCTTCAATGCCTTCGA
  CACCACTCAGACAGGCTCCGTGAAGTTCGAGGACTTTGTAACCGCTCTGTCGATTTTATT
  GAGAGGAACTGTCCACGAGAAACTAAGGTGGACATTTAATTTGTATGACATCAACAAGGA
  CGGATACATAAACAAAGAGGAGATGATGGACATTGTCAAAGCCATCTATGACATGATGGG
  GAAATACACATATCCTGTGCTCAAAGAGGACACTCCAAGGCAGCATGTGGACGTCTTCTT
  CCAGAAAATGGACAAAAATAAAGATGGCATCGTAACTTTAGATGAATTTCTTGAATCATG
  TCAGGAGGACGACAACATCATGAGGTCTCTCCAGCTGTTTCAAAATGTCATGTAACTGGT
  GACACTCAGCCATTCAGCTCTCAGAGACATTGTACTAAACAACCACCTTAACACCCTGAT
  CTGCCCTTGTTCTGATTTTACACACCAACTCTTGGGACAGAAACACCTTTTACACTTTGG
  AAGAATTCTCTGCTGAAGACTTTCTATGGAACCCAGCATCATGTGGCTCAGTCTCTGATT
  GCCAACTCTTCCTCTTTCTTCTTCTTGAGAGAGACAAGATGAAATTTGAGTTTGTTTTGG
  AAGCATGCTCATCTCCTCACACTGCTGCCCTATGGAAGTTCCCTCTGCTTAAGCTTAAAC
  AGTAGTGCACAAAATATGCTGCTTACGTGCCCCCAGCCCACTGCCTCCAAGTCAGGCAGA
  CCTTGGTGAATCTGGAAGCAAGAGGACCTGAGCCAGATGCACACCATCTCTGATGGCCTC
  CCAAACCAATGTGCCTGTTTCTCTTCCTTTGGTGGGAAGAATGAGAGTTATCCAGAACAA
  TTAGGATCTGTCATGACCAGATTGGGAGAGCCAGCACCTAACATATGTGGGATAGGACTG
  AATTATTAAGCATGACATTGTCTGATGACCCAAACTGCCCATGTCATTTGTTTCCAGAAA
  CGAGGACCAATAATTCTCTCACACTGGCATTTGTGCTGGTAGTACAAGTCCTTTAATATG
  TCCAGGAAGGGAGCCATTGCCCAGTGGTCCATATCTCCACCACATCCCCTGCTTGAGCCC
  AGCGCTGCATGTCCCTCCCAAGAAGTCCAGAATGCCTGCAAATTGCTGTAATTTTATACC
  ATGTTCTAACCAATAAACAGAACTATTTCTTACAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322651 unedited
  GTGAAACATTGTAGTATATTGTATACGACTCCTATAGGGCGGGAGGAAGATCGCGGGCGC
  CGGTACCGGTCCGGAATTCCCGGGATAGGCTCCAGGGCACCGTCCTCGGCCCTGGGCGAG
  GGAACCGCCGGGCCGGGTCCTCGCGCGGGGAAGCGGTTCCGAAGGCTCGCGGGGAGCGGC
  TAGCCCTGAGTCCCTGCATGTGCGGGGCTGAAGAAGGAAGCCAGAAGCCTCCTAGCCTCG
  CCTCCACGCTTGCTGAATACCAAGCTGCAGGCGAGCTGCCGGGCGCTTTTCTCTCCTCCA
  ATTCAGAGTAGACAAACCACGGGGATTTCTTTCCATTGTTTTGTTTAGGGGCCGGGCCCG
  GGGTCCCAACTCGCACTCAAGTCTTCGCTGCCATGGGGGCCGTCATGGGCACCTTCTCAT
  CTCTGCAAACCAAACAAAGGCGACCCTCGAAAGATAAGATTGAAGATGAGCTGGAGATGA
  CCATGGTTTGCCATCGGCCCGAGGGACTGGAGCAGCTCGAGGCCCAGACCAACTTCACCA
  AGAGGGAGCTGCAGGTCCTTTATCGAGGCTTCAAAAATGAGTGCCCCAGTGGTGTGGTCA
  ACGAAGACACATTCAAGCAGATCTATGCTCAGTTTTTCCCTCATGGAGATGCCAGCACGT
  ATGCCCATTACCTCTTCAATGCCTTCGACACCACTCAGACAGGCTCCGTGAAGTTCGAGG
  ACTTTGTAACCCGCTCTGTCGATTTTATGAGAGGAACTGTCCACGAGAACTAGGTGGACA
  TTAATTTGTATGACCTTCACAGGACGGATACTAAACAAGGAGGGAGATGATGACATTGTC
  AAGGCCTCTATGACCTGATGGGAAATACAGTAATTTCTGTGCCTCAAGAGGCACTCCAAG
  GGCACGAGTGGAGCTCTCTCTCCGAAATGCAAATAGAGTGGCATCGTACGTTAGTG
• Restriction Sites: Please inquire
• ACCN: NM_014592
• ORF Size: 651 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014592.2, NP_055407.1
• RefSeq Size: 2020
• RefSeq ORF: 651
• Locus ID: 30820
• Domains: EFh
• Protein Families: Druggable Genome, Ion Channels: Other
• Gene Summary: This gene encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
  Transcript Variant: This variant (2, also known as KCNP1-Ib deltaII) uses an alternate in-frame splice site in the 5' coding region compared to variant 5. It encodes isoform 2 which is shorter than isoform 5.