CPA5 (NM_001127441) Human Untagged Clone

CAT#: SC323064

CPA5 (untagged)-Human carboxypeptidase A5 (CPA5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CPA5
• Synonyms: FLJ35969
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001127441, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCAGGGCACCCCTGGAGGCGGGACGCGCCCTGGGCCATCCCCCGTGGACAGGCGGACACTCCTGGTCT
  TCAGCTTTATCCTGGCAGCAGCTTTGGGCCAAATGAATTTCACAGGGGACCAGGTTCTTCGAGTCCTGGC
  CAAAGATGAGAAGCAGCTTTCACTTCTCGGGGATCTGGAGGGCCTGAAACCCCAGAAGGTGGACTTCTGG
  CGTGGCCCAGCCAGGCCCAGCCTCCCTGTGGATATGAGAGTTCCTTTCTCTGAACTGAAAGACATCAAAG
  CTTATCTGGAGTCTCATGGACTTGCTTACAGCATCATGATAAAGGACATCCAGGTGCTGCTGGATGAGGA
  AAGACAGGCCATGGCGAAATCCCGCCGGCTGGAGCGCAGCACCAACAGCTTCAGTTACTCATCATACCAC
  ACCCTGGAGGAGATATATAGCTGGATTGACAACTTTGTAATGGAGCATTCCGATATTGTCTCAAAAATTC
  AGATTGGCAACAGCTTTGAAAACCAGTCCATTCTTGTCCTGAAGTTCAGCACTGGAGGTTCTCGGCACCC
  AGCCATCTGGATTGACACTGGAATTCACTCCCGGGAGTGGATCACCCATGCCACCGGCATCTGGACTGCC
  AATAAGATTGTCAGTGATTATGGCAAAGACCGTGTCCTGACAGACATACTGAATGCCATGGACATCTTCA
  TAGAGCTCGTCACAAACCCTGATGGGTTTGCTTTTACCCACAGCATGAACCGCTTATGGCGGAAGAACAA
  GTCCATCAGACCTGGAATCTTCTGCATCGGCGTGGATCTCAACAGGAACTGGAAGTCGGGTTTTGGAGGA
  AATGGTTCTAACAGCAACCCCTGCTCAGAAACTTATCACGGGCCCTCCCCTCAGTCGGAGCCGGAGGTGG
  CTGCCATAGTGAACTTCATCACAGCCCATGGCAACTTCAAGGCTCTGATCTCCATCCACAGCTACTCTCA
  GATGCTTATGTACCCTTACGGCCGATTGCTGGAGCCCGTTTCAAATCAGAGGGAGTTGTACGATCTTGCC
  AAGGATGCGGTGGAGGCCTTGTATAAGGTCCATGGGATCGAGTACATTTTTGGCAGCATCAGCACCACCC
  TCTATGTGGCCAGTGGGATCACCGTCGACTGGGCCTATGACAGTGGCATCAAGTACGCCTTCAGCTTTGA
  GCTCCGGGACACTGGGCAGTATGGCTTCCTGCTGCCGGCCACACAGATCATCCCCACGGCCCAGGAGACG
  TGGATGGCGCTTCGGACCATCATGGAGCACACCCTGAATCACCCCTACTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001127441
• ORF Size: 1311 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001127441.1, NP_001120913.1
• RefSeq Size: 2078
• RefSeq ORF: 1311
• Locus ID: 93979
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002 [PubMed 11836249]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 4 encode the same isoform (1).