HIPK4 (NM_144685) Human Untagged Clone
CAT#: SC323367
HIPK4 (untagged)-Kinase deficient mutant (K40M) of Human homeodomain interacting protein kinase 4 (HIPK4)
"NM_144685" in other vectors (7)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | HIPK4 |
Synonyms | FLJ32818 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC323367 sequence for NM_144685 edited (data generated by NextGen Sequencing)
ATGTCCACCATCCAGTCGGAGACTGACTGCTACGACATCATCGAGGTCTTGGGCAAGGGG ACCTTCGGGGAGGTAGCCAAGGGCTGGCGGCGGAGCACGGGCGAGATGGTGGCCATCATG ATCCTCAAGAATGACGCCTACCGCAACCGCATCATCAAAAACGAGCTGAAGCTGCTGCAC TGCATGCGAGGCCTAGACCCTGAAGAGGCCCACGTCATCCGCTTCCTTGAGTTCTTCCAT GACGCCCTCAAGTTCTACCTGGTCTTTGAGCTGCTGGAGCAAAACCTTTTCGAGTTCCAG AAGGAGAACAACTTCGCGCCCCTCCCCGCCCGCCACATCCGTACAGTCACCCTGCAGGTG CTCACAGCCCTGGCCCGGCTCAAGGAGCTGGCTATCATCCACGCTGATCTCAAGCCTGAG AACATCATGCTGGTGGACCAGACCCGCTGCCCCTTCAGGGTCAAGGTGATTGACTTCGGA TCCGCCAGCATTTTCAGCGAGGTGCGCTACGTGAAGGAGCCATACATCCAGTCGCGCTTC TACCGGGCCCCTGAGATCCTGCTGGGGCTGCCCTTCTGCGAGAAGGTGGACGTGTGGTCC CTGGGCTGCGTCATGGCTGAGCTGCACCTGGGCTGGCCTCTCTACCCCGGCAACAACGAG TACGACCAGGTGCGCTACATCTGCGAAACCCAGGGCCTGCCCAAGCCACACCTGTTGCAC GCCGCCTGCAAGGCCCACCACTTCTTCAAGCGCAACCCCCACCCTGACGCTGCCAACCCC TGGCAGCTCAAGTCCTCGGCTGACTACCTGGCCGAGACGAAGGTGCGCCCATTGGAGCGC CGCAAGTATATGCTCAAGTCGTTGGACCAGATTGAGACAGTGAATGGTGGCAGTGTGGCC AGTCGGCTAACCTTCCCTGACCGGGAGGCGCTGGCGGAGCACGCCGACCTCAAGAGCATG GTGGAGCTGATCAAGCGCATGCTGACCTGGGAGTCACACGAACGCATCAGCCCCAGTGCT GCCCTGCGCCACCCCTTCGTGTCCATGCAGCAGCTGCGCAGTGCCCACGAGACCACCCAC TACTACCAGCTCTCGCTGCGCAGCTACCGCCTCTCGCTGCAAGTGGAGGGGAAGCCCCCC ACGCCCGTCGTGGCCGCAGAAGATGGGACCCCCTACTACTGTCTGGCTGAGGAGAAGGAG GCTGCGGGTATGGGCAGTGTGGCCGGCAGCAGCCCCTTCTTCCGAGAGGAGAAGGCACCA GGTATGCAAAGAGCCATCGACCAGCTGGATGACCTGAGTCTGCAGGAGGCTGGGCATGGG CTGTGGGGTGAGACCTGCACCAATGCGGTCTCCGACATGATGGTCCCCCTCAAGGCAGCC ATCACTGGCCACCATGTGCCCGACTCGGGCCCTGAGCCCATCCTGGCCTTCTACAGCAGC CGCCTGGCAGGCCGCCACAAGGCCCGCAAGCCACCTGCGGGTTCCAAGTCCGACTCCAAC TTCAGCAACCTCATTCGGCTGAGCCAGGTCTCGCCTGAGGATGACAGGCCCTGCCGGGGC AGCAGCTGGGAGGAAGGAGAGCATCTCGGGGCCTCTGCTGAGCCACTGGCCATCCTGCAG CGAGATGAGGATGGGCCCAACATTGACAACATGACCATGGAAGCTGAGAGGCCAGACCCT GAGCTCTTCGACCCCAGCAGCTGTCCTGGAGAATGGCTGAGTGAGCCAGACTGCACCCTG GAGAGCGTCAGGGGCCCACGGGCTCAGGGGCTCCCACCCCGCCGCTCCCACCAGCATGGT CCACCCCGGGGGGCCACCAGCTTCCTCCAGCATGTCACCGGGCACCACTGA Clone variation with respect to NM_144685.3 119 a=>t >OriGene 5' read for mutant NM_144685 unedited
CCGCCGTTGAGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAAC CGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCATAACTTCGTATAGCATACATTATACGAAG TTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGAGAGCCACTCAACAGCGCTGGAAC CCATTCGGTGGGGCCTGGGGCCCCTCATCCCAAGCCAGGAGGGTTTCTGGGGAGGGGTGCAGCCCCCTGG GCAGACTGACAGTGTGGGCCTGGGGGGTTTTGGGGGTGCCAGGGAAACAGGGCCCAACCCCCTGGGGGGG GTGGGTTAAGTGCGGTTTTCCTTTTCCCCACTGGGGGCCCTCCGTATTTCCCCATAGGGGGGGGGGGGGG GGGGGGCAGAACCGGGGGACCCAGAAAAAAGGGAAAGCCGGTGTTCGAAAAGTGAGGGGGGAATTCAAGG AACAGGGGGAGGAAAGACCCCCCAAGAAACAAGCAGAAAGGGCGGGGGACAT >SC323367 kinase domain raw sequence. By performing BLASTX analysis with this sequence against NCBI refernce protein database, you can confirm the presence of the kinase-deficient mutation
CSTTGMGCAATGGGCGGTAGGCKGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCA GAATTTTGTAATACGACTCACTATAGGGCGGCCGCATAACTTCGTATAGCATACATTATACGAAGTTATG GATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGAGAGCCACTCAACAGCGCTGGAACCCATT CGGTGGGGCCTGGGGCCCCTCATCCCAAGCCAGGAGGGTTTCTGG |
Restriction Sites | Please inquire |
ACCN | NM_144685 |
ORF Size | 1851 bp |
Insert Size | 2472 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548. |
Reference Data | |
RefSeq | NM_144685.3, NP_653286.2 |
RefSeq Size | 2467 |
RefSeq ORF | 1851 |
Locus ID | 147746 |
Protein Families | Druggable Genome, Protein Kinase |
Gene Summary | This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53. [provided by RefSeq, Jul 2016] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC111529 | HIPK4 (untagged)-Human homeodomain interacting protein kinase 4 (HIPK4) |
USD 310.00 |
|
RC205549 | HIPK4 (Myc-DDK-tagged)-Human homeodomain interacting protein kinase 4 (HIPK4) |
USD 420.00 |
|
RG205549 | HIPK4 (GFP-tagged) - Human homeodomain interacting protein kinase 4 (HIPK4) |
USD 460.00 |
|
RC205549L1 | Lenti-ORF clone of HIPK4 (Myc-DDK-tagged)-Human homeodomain interacting protein kinase 4 (HIPK4) |
USD 768.00 |
|
RC205549L2 | Lenti-ORF clone of HIPK4 (mGFP-tagged)-Human homeodomain interacting protein kinase 4 (HIPK4) |
USD 620.00 |
|
RC205549L3 | Lenti-ORF clone of HIPK4 (Myc-DDK-tagged)-Human homeodomain interacting protein kinase 4 (HIPK4) |
USD 620.00 |
|
RC205549L4 | Lenti-ORF clone of HIPK4 (mGFP-tagged)-Human homeodomain interacting protein kinase 4 (HIPK4) |
USD 620.00 |
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