DYRK4 (NM_003845) Human Untagged Clone
CAT#: SC323557
DYRK4 (untagged)-Kinase deficient mutant (K133M) of Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4)
"NM_003845" in other vectors (7)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | DYRK4 |
Synonyms | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_003845, the custom clone sequence may differ by one or more nucleotides
ATGCCGGCCTCAGAGCTCAAGGCTTCAGAAATACCTTTCCACCCTAGCATTAAAACCCAGGATCCCAAGG CAGAGGAGAAGTCACCAAAGAAGCAAAAGGTGACTCTGACAGCGGCAGAGGCCCTAAAGCTTTTTAAGAA CCAGCTGTCTCCATATGAACAAAGTGAAATCCTGGGCTACGCGGAGCTGTGGTTCCTGGGTCTTGAAGCC AAGAAGCTCGACACGGCTCCTGAGAAATTTAGCAAGACGAGTTTTGATGATGAGCATGGCTTCTATCTGA AGGTCCTGCATGATCACATTGCCTACCGCTATGAAGTTCTGGAGACAATCGGGAAGGGGTCCTTTGGACA GGTGGCCAAGTGCTTGGATCACAAAAACAATGAGCTGGTGGCCCTGAAAATCATCAGGAACAAGAAGAGG TTTCACCAGCAGGCCCTGATGGAGCTGAAGATCCTGGAAGCTCTCAGAAAGAAGGACAAAGACAACACCT ACAATGTGGTGCATATGAAGGACTTTTTCTACTTTCGCAATCACTTCTGCATCACCTTTGAGCTCCTGGG AATCAACTTGTATGAGTTGATGAAGAATAACAACTTTCAAGGCTTCAGTCTGTCCATAGTTCGGCGCTTC ACTCTCTCTGTTTTGAAGTGCTTGCAGATGCTTTCGGTAGAGAAAATCATTCACTGTGATCTCAAGCCCG AAAATATAGTGCTATACCAAAAGGGCCAAGCCTCTGTTAAAGTCATTGACTTTGGATCAAGCTGTTATGA ACACCAGAAAGTATACACGTACATCCAAAGCCGGTTCTACCGATCCCCAGAAGTGATCCTGGGCCACCCC TACGACGTGGCCATTGACATGTGGAGCCTGGGCTGCATCACGGCGGAGTTGTACACGGGCTACCCCCTGT TCCCCGGGGAGAATGAGGTGGAGCAGCTGGCCTGCATCATGGAGGTGCTGGGTCTGCCGCCAGCCGGCTT CATTCAGACAGCCTCCAGGAGACAGACATTCTTTGATTCCAAAGGTTTTCCTAAAAATATAACCAACAAC AGGGGGAAAAAAAGATACCCAGATTCCAAGGACCTCACGATGGTGCTGAAAACCTATGACACCAGCTTCC TGGACTTTCTCAGAAGGTGTTTGGTATGGGAACCTTCTCTTCGCATGACCCCGGACCAGGCCCTCAAGCA TGCTTGGATTCATCAGTCTCGGAACCTCAAGCCACAGCCCAGGCCCCAGACCCTGAGGAAATCCAATTCC TTTTTCCCCTCTGAGACAAGGAAGGACAAGGTTCAAGGCTGTCATCACTCGAGCAGAAAAGCAGATGAGA TCACCAAAGAGACTACAGAGAAAACAAAAGATAGCCCCACGAAGCATGTTCAGCATTCAGGTGATCAGCA GGACTGTCTCCAGCACGGAGCTGACACTGTTCAGCTGCCTCAACTGGTAGACGCTCCCAAGAAGTCAGAG GCAGCTGTCGGGGCGGAGGTGTCCATGACCTCCCCAGGACAGAGCAAAAACTTCTCCCTCAAGAACACAA ACGTTTTACCCCCTATTGTATGA >OriGene 5' read for mutant NM_003845 unedited
CCGCCGTTTGAGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAA CCGTCAGAATCTTGTAATACGACTCACTATAGGGCGGCCGCATAACTTCGTATAGCATACATTATACGAA GCTTATGGATTCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGAGCGTGAGCTGTTGAAAGCCT GCAGCTAAACACCAGTGTTACTTCACTCCCCTTTGTGGACACCAAGGGGAAGAAGAATACGGTAAGCTTC CCACACATTAGCAAGAAAGTCCTGCTGAAGTCATCCCCTGCTGTATCAGGAGAATCAAGCTCACAATCAG ATGCCCGGCCTCAGAGCTCAAGGCTTCAGAAAATACCTTTCCACCCTAGCATTAAAACCCCAGGATCCCC AGGCAGAAGGAAAAGTCACCAAAGAGCCAAAGTTGACTCTGACACCGGCGAAGGCCCTAAAGCTTTTAAG AACCAGCTGTTTCCTTATGACAAAGTTGAATCCTGGGGCTACCCGGAGCTGTGGGTCCTGGGGCCTGGAC CAAGAAGTCGAACCGGTCTCGGAAAATTTACCAGAGCAGTTTGAGAGGAGACCTTGTTTCTACTGAAAGG TTCCATGGATCAATGCCCTACGATTGAAGTCCTAGACACTCCGGAAGGGTCCTTGACCGTGTCGCAAGCT CTGTTCACACACTATGCCGTGTGCCTTGATATACGAGACAAGAGTTACCCGCGCGTGAGCTAGATATCGG ACCCCAGAGACACAACCCATGGTGCTATAGAGATTCTCTCCCCTTGCCCCTGTCCGGACCTGTATAGAGA AACCTAGCGCTCGCATTTGCACTCTCGGTGATGCCGCACGGGGAAACCGGGGGG >SC323557 kinase domain raw sequence. By performing BLASTX analysis with this sequence against NCBI refernce protein database, you can confirm the presence of the kinase-deficient mutation
TMKATCATTGCCTACCGCTATGAGTTCTGGAGACAATCGGGAAGGGGTCCTTTGGACAGGTGGCCAAGTG CTTGGATCACAAAAACAATGAGCTGGTGGCCCTGATGATCATCAGGAACAAGAAGAGGTTTCACCAGCAG GCCCTGATGGAGCTGAAGATCCTGGAAGCTCTCAGAAAGAAGGACAAAGACAACACCTACAATGTGGTGC ATATGAAGGACTTTTTCTACTTTCGCAATCACTTCTGCATCACCT |
Restriction Sites | Please inquire |
ACCN | NM_003845 |
ORF Size | 1563 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548. |
Reference Data | |
RefSeq | NM_003845.1, NP_003836.1 |
RefSeq Size | 1860 |
RefSeq ORF | 1563 |
Locus ID | 8798 |
Protein Families | Druggable Genome, Protein Kinase |
Gene Summary | This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC106952 | DYRK4 (untagged)-Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) |
USD 310.00 |
|
RC206929 | DYRK4 (Myc-DDK-tagged)-Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) |
USD 420.00 |
|
RG206929 | DYRK4 (GFP-tagged) - Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) |
USD 460.00 |
|
RC206929L1 | Lenti ORF clone of Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4), Myc-DDK-tagged |
USD 768.00 |
|
RC206929L2 | Lenti ORF clone of Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4), mGFP tagged |
USD 620.00 |
|
RC206929L3 | Lenti ORF clone of Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4), Myc-DDK-tagged |
USD 620.00 |
|
RC206929L4 | Lenti ORF clone of Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4), mGFP tagged |
USD 620.00 |
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