HAT1 (NM_001033085) Human Untagged Clone

CAT#: SC324037

HAT1 (untagged)-Human histone acetyltransferase 1 (HAT1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HAT1
• Synonyms: histone acetyltransferase 1; KAT1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001033085.1 GAGCGCGCGGGTTGATTCGTCCTTCCTCAGCCGCGGGTGATCGTAGCTCGGAAATGGCGG
  GATTTGGTGCTATGGAGAAATTTTTGGTAGAATATAAGAGTGCAGTGGAGAAGAAACTGG
  CAGAGTACAAATGTAACACCAACACAGCAATTGAACTAAAATTAGTGAAACTGCTTTTGG
  TTACAAGGGTCTAAAGATCCTGTTATACTATATTGCTGGTAGCCTGTCAACAATGTTCCG
  TGTTGAATATGCATCTAAAGTTGATGAGAACTTTGACTGTGTAGAGGCAGATGATGTTGA
  GGGCAAAATTAGACAAATCATTCCACCTGGATTTTGCACAAACACGAATGATTTCCTTTC
  TTTACTGGAAAAGGAAGTTGATTTCAAGCCATTCGGAACCTTACTTCATACCTACTCAGT
  TCTCAGTCCAACAGGAGGAGAAAACTTTACCTTTCAGATATATAAGGCTGACATGACATG
  TAGAGGCTTTCGAGAATATCATGAAAGGCTTCAGACCTTTTTGATGTGGTTTATTGAAAC
  TGCTAGCTTTATTGACGTGGATGATGAAAGATGGCACTACTTTCTAGTATTTGAGAAGTA
  TAATAAGGATGGAGCTACGCTCTTTGCGACCGTAGGCTACATGACAGTCTATAATTACTA
  TGTGTACCCAGACAAAACCCGGCCACGTGTAAGTCAGATGCTGATTTTGACTCCATTTCA
  AGGTCAAGGCCATGGTGCTCAACTTCTTGAAACAGTTCATAGATACTACACTGAATTTCC
  TACAGTTCTTGATATTACAGCGGAAGATCCATCCAAAAGCTATGTGAAATTACGAGACTT
  TGTGCTTGTGAAGCTTTGTCAAGATTTGCCCTGTTTTTCCCGGGAAAAATTAATGCAAGG
  ATTCAATGAAGATATGGCGATAGAGGCACAACAGAAGTTCAAAATAAATAAGCAACACGC
  TAGAAGGGTTTATGAAATTCTTCGACTACTGGTAACTGACATGAGTGATGCCGAACAATA
  CAGAAGCTACAGACTGGATATTAAAAGAAGACTAATTAGCCCATATAAGAAAAAGCAGAG
  AGATCTTGCTAAGATGAGAAAATGTCTCAGACCAGAAGAACTGACAAACCAGATGAACCA
  AATAGAAATAAGCATGCAACATGAACAGCTGGAAGAGAGTTTTCAGGAACTAGTGGAAGA
  TTACCGGCGTGTTATTGAACGACTTGCTCAAGAGTAAAGATTATACTGCTCTGTACAGGA
  AGCTTGCAAATTTTCTGTACAATGTGCTGTGAAAAATCTGATGACTTTAATTTTAAAATC
  TTGTGACATTTTGCTTATACTAAAAGTTATCTATCTTTAGTTGAATATTTTCTTTTGGAG
  AGATTGTATATTTTAAAATACTGTTTAGAGTTTATGAGCATATATTGCATTTAAAGAAAG
  ATAAAGCTTCTGAAATACTACTGCAATTGCTTCCCTTCTTAAACAGTATAATAAATGCTT
  AGTTGTGATATGTTAATGTGTGATGATATGATTCTTAAATACTTACAATAAACCTCATTC
  TTAAATACTTAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001033085.1 unedited
  GGCACCTTGTATACGACTCCTATAGGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTC
  CGGAATTCCCGGGATGAGCGCGCGGGTTGATTCGTCCTTCCTCAGCCGCGGGTGATCGTA
  GCTCGGAAATGGCGGGATTTGGTGCTATGGAGAAATTTTTGGTAGAATATAAGAGTGCAG
  TGGAGAAGAAACTGGCAGAGTACAAATGTAACACCAACACAGCAATTGAACTAAAATTAG
  TGAAACTGCTTTTGGTTACAAGGGTCTAAAGATCCTGTTATACTATATTGCTGGTAGCCT
  GTCAACAATGTTCCGTGTTGAATATGCATCTAAAGTTGATGAGAACTTTGACTGTGTAGA
  GGCAGATGATGTTGAGGGCAAAATTAGACAAATCATTCCACCTGGATTTTGCACAAACAC
  GAATGATTTCCTTTCTTTACTGGAAAAGGAAGTTGATTTCAAGCCATTCGGAACCTTACT
  TCATACCTACTCAGTTCTCAGTCCAACAGGAGGAGAAAACTTTACCTTTCAGATATATAA
  GGCTGACATGACATGTAGAGGCTTTCGAGAATATCATGAAAGGCTTCAGACCTTTTTGAT
  GTGGTTTATTGAAACTGCTAGCTTTATTGACGTGGATGATGAAAGATGGCACTACTTTCT
  AGTATTTGAGAAGTATAATAAGGATGGAGCTACGCTCTTTGCGACCGTAGCTACATGACA
  GTCTATAATTACTATGTGTACCCAGACAAAACCCGGCCCACGTGTAAGTCAGATGCTGAT
  TTTGACTCCATTTCAAGGTCAAGGCCATGGTGCTCAACTTCTTGAAACAGTTCATAGATA
  CTACAACTGAATTTCCTACAGTTCTTGATATTACAGCCGGAGGATCCATCCAAAAGCTAA
  TGTGAACACGAAGAACTTTGTTGCTGGTGAAGCTTTGTCAGATTGCCCTTGTTTTCCCGG
  GAAAATAATGCCAGGATTCATTGAGAATTTGGCGGATGAGGCCACCGACGACGAAGT
• Restriction Sites: ECoRI-NOT
• ACCN: NM_001033085
• ORF Size: 1005 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001033085.1, NP_001028257.1
• RefSeq Size: 1596
• RefSeq ORF: 1005
• Locus ID: 8520
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009]
  Transcript Variant: This variant (2) lacks an alternate segment and uses a downstream start codon, compared to variant 1. Isoform b has a shorter N-terminus, compared to isoform a.