TCTN1 (NM_024549) Human Untagged Clone

CAT#: SC324085

TCTN1 (untagged)-Human tectonic family member 1 (TCTN1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TCTN1
• Synonyms: JBTS13; TECT1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_024549.4 GCAACGCGCTGTCCATGTCGCGGGCCTCGCTGGGACTCCCTGGGAGATGAGGCCGCGAGG
  TCTCCCGCCGCTCCTGGTGGTGCTCCTGGGCTGCTGGGCCTCCGTGAGCGCCCAGACCGA
  TGCCACCCCGGCGGTGACGACAGAGGGCCTCAACTCCACCGAGGCAGCCCTGGCCACCTT
  CGGAACTTTCCCGTCGACCAGGCCCCCCGGGACTCCCAGGGCTCCAGGGCCCTCCTCCGG
  CCCCAGGCCTACCCCAGTCACGGACGTTGCTGTTCTCTGTGTCTGTGACTTATCCCCAGC
  ACAGTGTGACATCAACTGCTGCTGTGATCCCGACTGCAGCTCCGTGGATTTCAGTGTCTT
  TTCTGCCTGCTCAGTTCCAGTTGTCACGGGCGACAGCCAGTTTTGTAGTCAAAAAGCAGT
  CATCTATTCATTGAATTTTACAGCAAACCCACCTCAAAGAGTATTTGAACTTGTTGACCA
  GATTAATCCATCTATTTTCTGCATTCATATTACAAACTATAAACCTGCATTATCCTTTAT
  TAATCCAGAAGTACCTGATGAAAACAATTTTGATACATTGATGAAAACATCTGATGGTTT
  TACATTGAATGCTGAATCATATGTTTCCTTCACAACCAAACTGGATATTCCTACTGCTGC
  TAAATATGAGTATGGGGTTCCTCTGCAGACTTCAGATTCGTTTCTGAGATTTCCTTCGTC
  CCTGACATCATCTCTGTGCACTGATAATAACCCTGCAGGCCAGGCGTACTGGTTCACACC
  TGTAATCCCAGCACTCTGGGAGGCCGAGGCGAGAGGATCACTTGAGGTACCTGATTCAAG
  AAAAAAGGTCCCTATCACTGTTCAGTCCATCGTCATTCAGTCTCTAAATAAAACGCTCAC
  CCGACGGGAGGACACTGATGTGCTGCAGCCGACTCTCGTCAACGCTGGACACTTTAGCCT
  TTGCGTGAATGTTGTTCTTGAGGTAAAGTACAGCCTCACATACACAGATGCAGGTGAAGT
  CACCAAAGCTGATCTCTCATTCGTTCTGGGGACAGTTAGCAGCGTAGTGGTCCCACTGCA
  GCAAAAGTTTGAAATTCATTTTCTTCAGGAAAATACCCAGCCAGTCCCTCTCAGTGGAAA
  CCCTGGTTATGTCGTGGGGCTCCCATTAGCTGCTGGATTCCAGCCTCATAAGGGGTCTGG
  GATTATTCAGACCACAAATAGATATGGACAGCTTACTATTCTTCATAGCACAACTGAGCA
  AGACTGCTTAGCACTGGAGGGGGTCCGGACCCCAGTATTATTTGGTTACACTATGCAATC
  TGGCTGTAAACTAAGACTGACTGGAGCTCTCCCGTGTCAGCTCGTAGCACAGAAGGTGAA
  GAGCCTGCTGTGGGGCCAGGGCTTCCCAGATTACGTGGCCCCTTTTGGAAATTCCCAGGC
  CCAGGACATGCTGGACTGGGTGCCCATCCACTTCATCACCCAGTCATTCAACAGGAAGGA
  TTCCTGCCAGCTCCCAGGGGCTTTGGTTATAGAAGTGAAGTGGACTAAATACGGATCCCT
  GCTGAATCCACAGGCCAAAATAGTCAATGTAACTGCAAATCTAATTTCATCCTCCTTTCC
  TGAGGCCAACTCAGGAAATGAAAGGACGATTCTTATTTCCACTGCGGTTACTTTTGTGGA
  TGTGTCTGCACCTGCAGAGGCAGGCTTCAGAGCTCCACCAGCCATCAATGCCAGGCTGCC
  CTTTAACTTCTTCTTCCCGTTTGTTTGACAATGCTCAGATGCATCAGTTCCTTAATATAC
  ACGTGAAATTTGAAAACTGTACATTCGGTGAGATTAAATTTTATATACAACTAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_024549.4 unedited
  GACGTTGTATACGACTCCTATAGGGCGGCCGGCGTATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGCGGGCAACGCGCTGTCCATGTCGCGGG
  CCTCGCTGGGACTCCCTGGGAGATGAGGCCGCGAGGTCTCCCGCCGCTCCTGGTGGTGCT
  CCTGGGCTGCTGGGCCTCCGTGAGCGCCCAGACCGATGCCACCCCGGCGGTGACGACAGA
  GGGCCTCAACTCCACCGAGGCAGCCCTGGCCACCTTCGGAACTTTCCCGTCGACCAGGCC
  CCCCGGGACTCCCAGGGCTCCAGGGCCCTCCTCCGGCCCCAGGCCTACCCCAGTCACGGA
  CGTTGCTGTTCTCTGTGTCTGTGACTTATCCCCAGCACAGTGTGACATCAACTGCTGCTG
  TGATCCCGACTGCAGCTCCGTGGATTTCAGTGTCTTTTCTGCCTGCTCAGTTCCAGTTGT
  CACGGGCGACAGCCAGTTTTGTAGTCAAAAAGCAGTCATCTATTCATTGAATTTTACAGC
  AAACCCACCTCAAAGAGTATTTGAACTTGTTGACCAGATTAATCCATCTATTTTCTGCAT
  TCATATTACAAACTATAAACCTGCATTATCCTTTATTAATCCAGAGTACCTGATGAAAAC
  AATTTTGATACATTGATGAAAACATCTGATGGTTTTACATTGAATGCTGAATCATATGTT
  TCCTTCACAACCAAACTGGATATTCCTACTGCTGCTAAATATGAGTATGGGGTTCCTCTG
  CAGACTTCAGATTCGTTCTGAGATTTCTTCGTCCCTGACATCATCTCTGTGCACTGATAA
  TAACCCTGCAGCCAGGCGTACTGTTCACACCTTGTAATCCAAGCACTCTGGGAGCCGAGC
  CGAAGAGATCACTTGAGTTACCTGATTCAGAAAAAAGGTCCCTATCCTGTTCAGCCACTC
  GTCTTTACA
• Restriction Sites: ECoRI-NOT
• ACCN: NM_024549
• ORF Size: 1722 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_024549.4, NP_078825.2
• RefSeq Size: 1935
• RefSeq ORF: 1722
• Locus ID: 79600
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (3) lacks an exon and contains an alternate in-frame exon in the central coding region and an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 3).