ACCN4 (ASIC4) (NM_182847) Human Untagged Clone

CAT#: SC324144

ASIC4 (untagged)-Human amiloride-sensitive cation channel 4, pituitary (ACCN4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ASIC4
• Synonyms: ACCN4; BNAC4
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_182847.1 GGGCTCCGGAGCACATGCTGAGCGGAGCGGCTGGGGCTGCGCGGCGTGGCGGAGCAGCGC
  TCGCTCCCTCGCTCACTCGCTCGCTCGCAGGGACACACGCAGGGGCTGACAGCTGTGCTG
  GTGCTGATAAGGGAAGCCACAAGGAGACGATCGAGGAGAGAGACAAGCGGCAGCAGAGGC
  AGCAGCGGCAGAGGCAGCACCAGGGCTGCGGAGCTGCTGGGAGTGGGAGTGACTCCCCCA
  CCTCGGGCCCCCACCCTGTCCCTGTCCTCTTCCCGCTTGCCCTGAGTTTAGAAGAGCAGC
  CGCTGCCACCACTGCCACTCGGGAGGGCACCAGGGCTGCTGGCTAGGGAGGGACAGGGCA
  GGGAGGCTCTGGCCAGTCCCAGCAGCCGGGGACAGATGCCGATCGAGATTGTGTGCAAAA
  TCAAATTTGCTGAGGAGGATGCGAAACCCAAGGAGAAGGAGGCAGGGGATGAGCAGAGCC
  TCCTCGGGGCTGTTGCCCCTGGAGCAGCCCCCCGAGACCTGGCCACCTTTGCCAGCACCA
  GCACCCTGCATGGACTGGGCCGGGCCTGTGGCCCAGGCCCCCACGGACTGCGCAGAACCC
  TGTGGGCACTGGCCCTACTCACCTCGCTGGCTGCCTTCCTGTACCAGGCGGCTGGCCTGG
  CCCGGGGCTACCTGACCCGGCCTCACCTGGTGGCAATGGACCCCGCTGCCCCAGCCCCAG
  TGGCGGGCTTCCCGGCTGTCACCCTCTGCAATATCAACCGCTTCCGGCATTCGGCACTCA
  GCGATGCCGACATCTTCCACCTGGCCAATCTGACAGGGCTGCCCCCCAAAGACCGGGATG
  GGCACCGTGCGGCTGGCCTGCGCTACCCAGAGCCTGACATGGTAGACATCCTCAACCGCA
  CTGGCCACCAGCTCGCCGACATGCTTAAGAGCTGCAACTTCAGTGGGCATCACTGCTCCG
  CCAGCAACTTCTCTGTGGTCTATACTCGCTATGGGAAGTGTTACACCTTCAACGCGGACC
  CGCGGAGCTCGCTGCCCAGCCGGGCAGGGGGCATGGGCAGTGGCCTGGAGATCATGCTGG
  ACATCCAGCAGGAGGAGTACCTGCCCATCTGGAGGGAGACAAATGAGACGTCGTTTGAGG
  CAGGTATTCGGGTGCAGATCCACAGCCAGGAGGAGCCGCCCTACATCCACCAGCTGGGGT
  TCGGGGTGTCCCCAGGCTTCCAGACCTTTGTGTCCTGCCAGGAACAGCGGCTGACCTACC
  TGCCCCAGCCCTGGGGCAACTGCCGCGCAGAGAGTGAGCTCAGGGAGCCTGAGCTTCAGG
  GCTACTCGGCCTACAGTGTGTCTGCCTGCCGGCTGCGCTGTGAAAAGGAGGCCGTGCTTC
  AGCGCTGCCACTGCCGGATGGTGCACATGCCAGACTCCCTGGGTGGGGGCCCTGAGGGCC
  CGTGCTTCTGCCCCACCCCCTGCAACCTGACACGCTATGGGAAAGAGATCTCCATGGTCA
  GGATCCCCAACAGGGGCTCAGCCCGGTACCTGGCGAGGAAGTACAACCGCAACGAGACCT
  ACATACGGGAGAACTTCCTGGTCCTAGATGTCTTCTTTGAGGCCCTGACCTCTGAAGCCA
  TGGAGCAGCGAGCAGCCTATGGCCTGTCAGCCCTGCTGGGAGACCTCGGGGGACAGATGG
  GCCTGTTCATTGGGGCCAGCATCCTCACGTTGCTGGAGATCCTCGACTACATCTATGAGG
  TGTCCTGGGATCGACTGAAGCGGGTATGGAGGCGTCCCAAGACCCCCCTGCGGACCTCCA
  CTGGGGGCATCTCCACTTTGGGGCTTCAGGAGCTGAAGGAACAGAGTCCCTGCCCGAGCC
  TGGGCCGAGCGGAGGGTGGGGGGGTCAGCAGTCTGCTCCCCAATCACCACCACCCCCACG
  GTCCCCCAGGAGGTCTCTTTGAAGATTTTGCTTGCTAGGACGGTGCTGTGACTGAAAGGA
  CCCAGGAGTCTGGGACCCCTCCTGGGATCCCCAGCACATTCTCCTGCTCCTGGGAGAGGC
  CTGGGGGCGGTGCTCACTGGGAGGGCCAGGACTCAGTTCCTGCTCTCATCCTCCCCTGCC
  CTGATGTCAGCTGCTTTGCACAAAGGTCCTTCTTGTCCACACCCCTTATCCCCAGGCTGG
  TGCCCCGGGAGGGCTGGAGACCAGGCCATGGGCCCTCACGGAGAGGAAGGGAAGGAAGGA
  GAGGGAGGGGGAGGATAGAGCCCATCCCAGCCGGGGAGGGGGAGCCCTCTGTACATTTGT
  AAATATTTAGGGAAAGCCGGGTGGGGGGAGGGGATACAGATGTAGAAGGTGGGTAGGGCT
  ACAGGGGTGGGTGATTTAGGGACAGCCAGGGTCCCAGCCCCAATGTCAGCAGGATAGGGA
  GAGCCCCAGGACTCAGGAGTGCTGGGCTGGTCCTACTTCCTGCCCCTCTCCAGGCCCAGC
  TCCCCTCTTGGCAGGGGGAGAGGATGGCCCAGCAGGCCTGGCCCAGCTCCCAGTTCCCCC
  TGCACCAGCCCCACCCCTAGAGTCCCTTCTATAGGGAGGGGGCAGGAGACCTTCCAGACT
  TCGGCTGAGCTTGGAGGGTGGGAAGGGAGCCTTCTCAGTCCTCTCTCCCTCCAGTCTGAT
  TTTATAAAGTGCTGACGAGATTGGGAATAAAGAGGCATAAAGAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_182847.1 unedited
  GACCATTGTAATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCC
  GGAATTCCCGGGATATCGTCGACCCACGCGTCCGGGGCTCCGGAGCACATGCTGAGCGGA
  GCGGCTGGGGCTGCGCGGCGTGGCGGAGCAGCGCTCGCTCCCTCGCTCACTCGCTCGCTC
  GCAGGGACACACGCAGGGGCTGACAGCTGTGCTGGTGCTGATAAGGGAAGCCACAAGGAG
  ACGATCGAGGAGAGAGACAAGCGGCAGCAGAGGCAGCAGCGGCAGAGGCAGCACCAGGGC
  TGCGGAGCTGCTGGGAGTGGGAGTGACTCCCCCACCTCGGGCCCCCACCCTGTCCCTGTC
  CTCTTCCCGCTTGCCCTGAGTTTAGAAGAGCAGCCGCTGCCACCACTGCCACTCGGGAGG
  GCACCAGGGCTGCTGGCTAGGGAGGGACAGGGCAGGGAGGCTCTGGCCAGTCCCAGCAGC
  CGGGGACAGATGCCGATCGAGATTGTGTGCAAAATCAAATTTGCTGAGGAGGATGCGAAA
  CCCAAGGAGAAGGAGGCAGGGGATGAGCAGAGCCTCCTCGGGGCTGTTGCCCCTGGAGCA
  GCCCCCCCGAGACCTGGCCACCTTTGCCAGCACCAGCACCCTGCATGGACTGGGCCGGGC
  CCTGTGGCCCAGGCCCCCACGGACTGCGCAGAACCCTGTGGGCACTGGCCCTACTCACCT
  CGCTGGCTGCCTTTCCTGTACAAGCGGCTGGCCTGGCCCGGTGCTACCTGACCGGCCTCA
  CTTGGGGGCAATGGGACCCGCTGCCTCAGCCCAGTGGGCGGCTTTCC
• Restriction Sites: ECoRI-NOT
• ACCN: NM_182847
• ORF Size: 1944 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_182847.1, NP_878267.1
• RefSeq Size: 2697
• RefSeq ORF: 1944
• Locus ID: 55515
• Protein Families: Druggable Genome, Ion Channels: Other
• Gene Summary: This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]
  Transcript Variant: This variant (2) lacks an exon in the central coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.