ARPC1A (NM_006409) Human Untagged Clone

CAT#: SC324215

ARPC1A (untagged)-Human actin related protein 2/3 complex, subunit 1A, 41kDa (ARPC1A), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARPC1A
• Synonyms: Arc40; HEL-68; HEL-S-307; SOP2Hs; SOP2L
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006409.2 GTCCTCCGCCCGCGCCCGACGGAGCCTGTTCGCGTCGACTGCCCAGAGTCCGCGAATCCT
  CCGCTCCGAGCCCGTCCGGACTCCCCCGATCCCAGCTTTCTCTCCTTTGAAAACACTAAG
  AATAATGTCACTGCATCAGTTTTTACTAGAGCCAATCACCTGTCATGCCTGGAACAGGGA
  TCGTACTCAGATTGCCCTCAGTCCCAATAATCACGAAGTGCACATCTATAAGAAGAACGG
  GAGCCAGTGGGTGAAAGCTCATGAACTCAAGGAGCACAACGGACACATCACAGGTATTGA
  CTGGGCTCCCAAGAGCGACCGCATTGTCACTTGTGGGGCAGACCGCAATGCCTATGTCTG
  GAGTCAGAAAGATGGTGTTTGGAAGCCAACCCTGGTGATCCTGAGAATTAATCGCGCAGC
  TACTTTTGTGAAGTGGTCCCCCCTAGAGAACAAATTTGCTGTGGGAAGTGGAGCACGACT
  CATTTCTGTTTGTTACTTTGAGTCTGAAAATGACTGGTGGGTGAGCAAGCACATTAAAAA
  GCCGATTCGCTCCACAGTCCTCAGCTTGGATTGGCATCCCAACAACGTTTTGCTGGCAGC
  AGGATCATGTGACTTCAAATGCAGAGTGTTTTCTGCCTACATTAAAGAAGTGGATGAAAA
  GCCAGCCAGCACGCCCTGGGGCAGCAAGATGCCTTTTGGGCAGCTGATGTCAGAGTTTGG
  TGGCAGTGGCACTGGTGGCTGGGTCCACGGGGTAAGCTTCTCTGCCAGTGGGAGCCGCCT
  GGCCTGGGTCAGCCACGACAGCACCGTGTCTGTTGCTGATGCCTCAAAAAGTGTGCAGGT
  CTCGACTCTGAAGACAGAGTTCCTGCCGCTCCTAAGTGTGTCATTTGTCTCAGAGAACAG
  CGTCGTGGCTGCTGGCCATGACTGCTGCCCAATGCTCTTTAACTACGATGACCGCGGCTG
  CCTGACCTTCGTCTCCAAGTTAGATATTCCAAAACAGAGCATCCAACGCAACATGTCTGC
  CATGGAACGCTTCCGCAACATGGACAAGAGAGCCACAACTGAGGACCGCAACACGGCCTT
  GGAGACGCTGCACCAGAATAGCATCACTCAAGTCTCTATTTATGAGGTGGACAAGCAAGA
  TTGTCGCAAATTTTGCACTACTGGCATCGATGGAGCCATGACAATTTGGGATTTCAAGAC
  CCTCGAGTCTTCCATCCAGGGCCTCCGGATAATGTGAAGCTGAGTGAGCCTCCGCCATCC
  AGCATGACAAACTGTGGCCGACCGCAGCTGTGCCGTGGCACGATGGCGAGGAAGCCAGCC
  CCAAGGAAACACTGAAAACACATATCACGCCAATGCCGTGTGGTTTTGTTTGAATATAAA
  ATTGGTGAAAGTGTTGGTTTTTTTAAGGCAGTAATTTTTTTGTTTGTTTTTTTGCGATTT
  CATTCCATTCTTGACCAAAGCTTCTCTTTAAGTAGTTTATTATGGAAAATTGTCACACTA
  ACTTAAAAGACAGGGTGAGGGAGATATGTAAATTGTCCACTAGAAAATTAAATAAAAGAA
  CTGAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006409.2 unedited
  GGCACATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCC
  GGAATTCCCGGGATATCGTCGACCCACGCGTCCGGTCCTCCGCCCGCGCCCGACGGAGCC
  TGTTCGCGTCGACTGCCCAGAGTCCGCGAATCCTCCGCTCCGAGCCCGTCCGGACTCCCC
  CGATCCCAGCTTTCTCTCCTTTGAAAACACTAAGAATAATGTCACTGCATCAGTTTTTAC
  TAGAGCCAATCACCTGTCATGCCTGGAACAGGGATCGTACTCAGATTGCCCTCAGTCCCA
  ATAATCACGAAGTGCACATCTATAAGAAGAACGGGGGCCTGTGGTTTGGGGCGGGGAACT
  GAAGGACCTCAACGGAAACATCACATGACTCGA
• Restriction Sites: ECoRI-NOT
• ACCN: NM_006409
• ORF Size: 1113 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006409.2, NP_006400.2
• RefSeq Size: 1619
• RefSeq ORF: 1113
• Locus ID: 10552
• Domains: WD40
• Protein Pathways: Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton
• Gene Summary: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
  Transcript Variant: This variant (1) encodes the longer isoform (1).