DOLK (NM_014908) Human Untagged Clone

CAT#: SC324302

DOLK (untagged)-Human dolichol kinase (DOLK)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DOLK
• Synonyms: CDG1M; DK; DK1; SEC59; TMEM15
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014908.3 CAAAGAGGTGAGGAGCCGGCAGCGGGGGCGGCTGTAACTGTGAGGAAGGCTGCAGAGTGG
  CGACGTCTACGCCGTAGGTTGGAGGCTGTGGGGGGTGGCCGGGCGCCAGCTCCCAGGCCG
  CAGAAGTGACCTGCGGTGGAGTTCCCTCCTCGCTGCTGGAGAACGGAGGGAGAAGGTTGC
  TGGCCGGGTGAAAGTGCCTCCCTCTGCTTGACGGGGCTGAGGGGCCCGAAGTCTAGGGCG
  TCCGTAGTCGCCCCGGCCTCCGTGAAGCCCCAGGTCTAGAGATATGACCCGAGAGTGCCC
  ATCTCCGGCCCCGGGGCCTGGGGCTCCGCTGAGTGGATCGGTGCTGGCAGAGGCGGCAGT
  AGTGTTTGCAGTGGTGCTGAGCATCCACGCAACCGTATGGGACCGATACTCGTGGTGCGC
  CGTGGCCCTCGCAGTGCAGGCCTTCTACGTCCAATACAAGTGGGACCGGCTGCTACAGCA
  GGGAAGCGCCGTCTTCCAGTTCCGAATGTCCGCAAACAGTGGCCTATTGCCCGCCTCCAT
  GGTCATGCCTTTGCTTGGACTAGTCATGAAGGAGCGGTGCCAGACTGCTGGGAACCCGTT
  CTTTGAGCGTTTTGGCATTGTGGTGGCAGCCACTGGCATGGCAGTGGCCCTCTTCTCATC
  AGTGTTGGCGCTCGGCATCACTCGCCCAGTGCCAACCAACACTTGTGTCATCTTGGGCTT
  GGCTGGAGGTGTTATCATTTATATCATGAAGCACTCGTTGAGCGTGGGGGAGGTGATCGA
  AGTCCTGGAAGTCCTTCTGATCTTCGTTTATCTCAACATGATCCTGCTGTACCTGCTGCC
  CCGCTGCTTCACCCCTGGTGAGGCACTGCTGGTATTGGGTGGCATTAGCTTTGTCCTCAA
  CCAGCTCATCAAGCGCTCTCTGACACTGGTGGAAAGTCAGGGGGACCCAGTGGACTTCTT
  CCTGCTGGTGGTGGTAGTAGGGATGGTACTCATGGGCATTTTCTTCAGCACTCTGTTTGT
  CTTCATGGACTCAGGCACCTGGGCCTCCTCCATCTTCTTCCACCTCATGACCTGTGTGCT
  GAGCCTTGGTGTGGTCCTACCCTGGCTGCACCGGCTCATCCGCAGGAATCCCCTGCTCTG
  GCTTCTTCAGTTTCTCTTCCAGACAGACACCCGCATCTACCTCCTAGCCTATTGGTCTCT
  GCTGGCCACCTTGGCCTGCCTGGTGGTGCTGTACCAGAATGCCAAGCGGTCATCTTCCGA
  GTCCAAGAAGCACCAGGCCCCCACCATCGCCCGAAAGTATTTCCACCTCATTGTGGTAGC
  CACCTACATCCCAGGTATCATCTTTGACCGGCCACTGCTCTATGTAGCCGCCACTGTATG
  CCTGGCGGTCTTCATCTTCCTGGAGTATGTGCGCTACTTCCGCATCAAGCCTTTGGGTCA
  CACTCTACGGAGCTTCCTGTCCCTTTTTCTGGATGAACGAGACAGTGGACCACTCATTCT
  GACACACATCTACCTGCTCCTGGGCATGTCTCTTCCCATCTGGCTGATCCCCAGACCCTG
  CACACAGAAGGGTAGCCTGGGAGGAGCCAGGGCCCTCGTCCCCTATGCCGGTGTCCTGGC
  TGTGGGTGTGGGTGATACTGTGGCCTCCATCTTCGGTAGCACCATGGGGGAGATCCGCTG
  GCCTGGAACCAAAAAGACTTTTGAGGGGACCATGACATCTATATTTGCGCAGATCATTTC
  TGTAGCTCTGATCTTAATCTTTGACAGTGGAGTGGACCTAAACTACAGTTATGCTTGGAT
  TTTGGGGTCCATCAGCACTGTGTCCCTCCTGGAAGCATACACTACACAGATAGACAATCT
  CCTTCTGCCTCTCTACCTCCTGATATTGCTGATGGCCTAGCTGTTACAGTGCAGCAGCAG
  TGACGGAGGAAACAGACATGGGGAGGGTGAACAGTCCCCACAGCAGACAGCTACTTGGGC
  ATGAAGAGCCAAGGTGTGAAAAGCAGATTTGATTTTTCAGTTGATTCAGATTTAAAATAA
  AAAGCAAAGCTCTCCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014908.3 unedited
  GTACCTAGCCCTGTAAGCCTCCCGCTGTTTTGACCTCCATAGAAGACACCGGGACCGATC
  CAGCCTCCGGACTCTAGCCTAGGCCGCGGGACGGATAACAATTTCACACAGGAAACAGCT
  ATGACCATTAGGCCTATTTAGGTGACACTATAGAACAAGTTTGTACAAAAAAGCAGGCTG
  GTACCGGTCCGGAATTCCCGGGATCAAAGAGGTGAGGAGCCGGCAGCGGGGGCGGCTGTA
  ACTGTGAGGAAGGCTGCAGAGTGGCGACGTCTACGCCGTAGGTTGGAGGCTGTGGGGGGT
  GGCCGGGCGCCAGCTCCCAGGCCGCAGAAGTGACCTGCGGTGGAGTTCCCTCCTCGCTGC
  TGGAGAACGGAGGGAGAAGGTTGCTGGCCGGGTGAAAGTGCCTCCCTCTGCTTGACGGGG
  CTGAGGGGCCCGAAGTCTAGGGCGTCCGTAGTCGCCCCGGCCTCCGTGAAGCCCCAGGTC
  TAGAGATATGACCCGAGAGTGCCCATCTCCGGCCCCGGGGCCTGGGGCTCCGCTGAGTGG
  ATCGGTGCTGGCAGAGGCGGCAGTAGTGTTTGCAGTGGTGCTGAGCATCCACGCAACCGT
  ATGGGACCGATACTCGTGGTGCGCCGTGGCCCTCGCAGTGCAGGCCTTCTACGTCCAATA
  CAAGTGGGGACCGGCTGCTACAGCAGGGAAGCGCCGTCTTCCAGTTCCGAATGTCCGCAA
  ACAGTGGCCCTATTGCCCGCCTCCATGGTCATGCCTTTGCTTGGACTAGTCATGAAGGAG
  CGTGCCAGACTGCTGGGAACCCGTTCTTTGAGCGTTTTGGCATTGTGTTGCAGCCACTGC
  CATGGCAGTGACCCTCTTCTCATCAGTGTTGGCGCTCGGCATCACTTCGCCCAGTGGCCA
  GCACACCTTGGTGTCATCTTGGCCTTGCCTGGAAGTGTTATCATTTAATTTCATGAACCC
  ATCTCGTTGACCGGTGGGGGAGTCG
• Restriction Sites: Please inquire
• ACCN: NM_014908
• ORF Size: 1617 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014908.3, NP_055723.1
• RefSeq Size: 2267
• RefSeq ORF: 1617
• Locus ID: 22845
• Protein Families: Transmembrane
• Gene Summary: The protein encoded by this gene catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency. [provided by RefSeq, Apr 2010]