NORE1 (RASSF5) (NM_182665) Human Untagged Clone

CAT#: SC324315

RASSF5 (untagged)-Human Ras association (RalGDS/AF-6) domain family member 5 (RASSF5), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RASSF5
• Synonyms: Maxp1; NORE1; NORE1A; NORE1B; RAPL; RASSF3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_182665.2 GCAGGAAAGGCGCGGGAGGCGGGGGAGGTGCGGAGATGGCGCTCTGCACGGCGGCGGAGG
  GAGGGCGCTGGCGCCGGGGACACGAAACCGCAGAGCCCGGACGAGTCAGGGAGTGAGGCG
  CGAGCCGGGCGCCCGGGGCTCTGCAGGCGCAGGCGGCGCGGGGACAGGAGCAGGTTACCG
  GGCCGCCCGAGCGCTCGCACCCCGCTGAAAGAAACGCAGGCGGCCCGCCGGCTCTGCCTG
  GTCCGCTACCCGACCAGCTCCCGGCTCGGGGCTCAGAGCTAGGGGCTTACGCCAAGCGGA
  GCCCGGGGAGGGGTGCCCACCTCCCTCCGCCGCATCCCAAGCCCGGCCCCCTTGATGCGC
  TGGCGGCCTCGGCCGGGAACTCCGGGGTAGATGACCGTGGACAGCAGCATGAGCAGTGGG
  TACTGCAGCCTGGACGAGGAACTGGAAGACTGCTTCTTCACTGCTAAGACTACCTTTTTC
  AGAAATGCGCAGAGCAAACATCTTTCAAAGAATGTCTGTAAACCTGTGGAGGAGACACAG
  CGCCCGCCCACACTGCAGGAGATCAAGCAGAAGATCGACAGCTACAACACGCGAGAGAAG
  AACTGCCTGGGCATGAAACTGAGTGAAGACGGCACCTACACGGGTTTCATCAAAGTGCAT
  CTGAAACTCCGGCGGCCTGTGACGGTGCCTGCTGGGATCCGGCCCCAGTCCATCTATGAT
  GCCATCAAGGAGGTGAACCTGGCGGCTACCACGGACAAGCGGACATCCTTCTACCTGCCC
  CTAGATGCCATCAAGCAGCTGCACATCAGCAGCACCACCACCGTCAGTGAGGTCATCCAG
  GGGCTGCTCAAGAAGTTCATGGTTGTGGACAATCCCCAGAAGTTTGCACTTTTTAAGCGG
  ATACACAAGGACGGACAAGTGCTCTTCCAGAAACTCTCCATTGCTGACCGCCCCCTCTAC
  CTGCGCCTGCTTGCTGGGCCTGACACGGAGGTCCTCAGCTTTGTGCTAAAGGAGAATGAA
  ACTGGAGAGGTAGAGTGGGATGCCTTCTCCATCCCTGAACTTCAGAACTTCCTAACAATC
  CTGGAAAAAGAGGAGCAGGACAAAATCCAACAAGTGCAAAAGAAGTATGACAAGTTTAGG
  CAGAAACTGGAGGAGGCCTTAAGAGAATCCCAGGGCAAACCTGGGTAACCGGTCCTGCTT
  CCTCTCCTCCTGGTGCATTCAGATTTATTTGTATTATTAATTATTATTTTGCAACAGACA
  CTTTTTCTCAGGACATCTCTGGCAGGTGCATTTGTGCCTGCCCAGCAGTTCCAGCTGTGG
  CAAAAGTCTCTTCCATGGACAAGTGTTTGCACGAGGGTTCAGCTGTGCCCGCCCCCAGGC
  TGTGCCCCACCACAGATTCTGCCAAGGATCAGAACTCATGTGAAACAAACAGCTGACGTC
  CTCTCTCGATCTGCAAGCCTTTCACCAACCAAATAGTTGCCTCTCTCGTCACCAAACTGG
  AACCTCACACCAGCCGGCAAAGGAAGGAAGAAAGGTTTTAGAGCTGTGTGTTCTTTCTCT
  GGCATTGATTCCTCTTTGAGTTCTCTTACTTGCCACGTACAGGACCATTATTTATGAGTG
  AAAAGCTGTAGCACATTCCTTTTGCAGGTCTGAGCTAAGCCCCTGAAAGCAGGGTAATGC
  TCATAAAAGGACTGTTCCCGCGGCCCCAAGGTGCCTGTTGTTCACACTTAAGGGAAGTTT
  ATAAAGCTACTGGCCCCAGATGCTCAGGGTAAGGAGCACCAAAGCTGAGGCTGGCTCAGA
  GATCTCCAGAGAAGCTGCAGCCTGCCCTGGCCCTGGCTCTGGCCCTGGCCCACATTGCAC
  ATGGAAACCCAAAGGCATATATCTGCGTATGTGTGGTACTTAGTCACATCTTTGTCAACA
  AACTGTTCGTTTTTAAGTTACAAATTTGAATTTAATGTTGTCATCATCGTCATGTGTTTC
  CCCAAAGGGAAGCCAGTCATTGACCATTTAAAAAGTCTCCTGCTAAGTATGGAAATCAGA
  CAGTAAGAGAAAGCCAAAAAGCAATGCAGAGAAAGGTGTCCAAGCTGTCTTCAGCCTTCC
  CCAGCTAAAGAGCAGAGGAGGGCCTGGGCTACTTGGGTTCCCCATCGGCCTCCAGCACTG
  CCTCCCTCCTCCCACTGCGACTCTGGGATCTCCAGGTGCTGCCCAAGGAGTTGCCTTGAT
  TACAGAGAGGGGAGCCTCCAATTCGGCCAACTTGGAGTCCTTTCTGTTTTGAAGCATGGG
  CCAGACCCGGCACTGCGCTCGGAGAGCCGGTGGGCCTGGCCTCCCCGTCGACCTCAGTGC
  CTTTTTGTTTTCAGAGAGAAATAGGAGTAGGGCGAGTTTGCCTGAAGCTCTGCTGCTGGC
  TTCTCCTGCCAGGAAGTGAACAATGGCGGCGGTGTGGGAGACAAGGCCAGGAGAGCCCGC
  GTTCAGTATGGGTTGAGGGTCACAGACCTCCCTCCCATCTGGGTGCCTGAGTTTTGACTC
  CAATCAGTGATACCAGACCACATTGACAGGGAGGATCAAATTCCTGACTTACATTTGCAC
  TGGCTTCTTGTTTAGGCTGAATCCTAAAATAAATTAGTCAAAAAATTCCAACAAGTAGCC
  AGGACTGCAGAGACACTCCAGTGCAGAGGGAGAAGGACTTGTAATTTTCAAAGCAGGGCT
  GGTTTTCCAACCCAGCCTCTGAGAAACCATTTCTTTGCTATCCTCTGCCTTCCCAAGTCC
  CTCTTGGGTCGGTTCAAGCCCAAGCTTGTTCGTGTAGCTTCAGAAGTTCCCTCTCTGACC
  CAGGCTGAGTCCATACTGCCCCTGATCCCAGAAGGAATGCTGACCCCTCGTCGTATGAAC
  TGTGCATAGTCTCCAGAGCTTCAAAGGCAACACAAGCTCGCAACTCTAAGATTTTTTTAA
  ACCACAAAAACCCTGGTTAGCCATCTCATGCTCAGCCTTATCACTTCCCTCCCTTTAGAA
  ACTCTCTCCCTGCTGTATATTAAAGGGAGCAGGTGGAGAGTCATTTTCCTTCGTCCTGCA
  TGTCTCTAACATTAATAGAAGGCATGGCTCCTGCTGCAACCGCTGTGAATGCTGCTGAGA
  ACCTCCCTCTATGGGGATGGCTATTTTATTTTTGAGAAGGAAAAAAAAAGTCATGTATAT
  ATACACATAAAGGCATATAGCTATATATAAAGAGATAAGGGTGTTTATGAAATGAGAAAA
  TTATTGGACAATTCAGACTTTACTAAAGCACAGTTAGACCCAAGGCCTATGCTGAGGTCT
  AAACCTCTGAAAAAAGTATAGTATCGAGTACCCGTTCCCTCCCAGAGGTGGGAGTAACTG
  CTGGTAGTGCCTTCTTTGGTTGTGTTGCTCAGTGTGTAAGTGTTTGTTTCCAGGATATTT
  TCTTTTTAAATGTCTTTCTTATATGGGTTTTAAAAAAAAGTAATAAAAGCCTGTTGCAAA
  AAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_182665.2 unedited
  TGCCCAAGCCTGTAAGCATCCCGCATGTTTTGACCTCCATAGAAGACACCGGGACCGATC
  CAGCCTCCGGACTCTAGCCTAGGCCGCGGGACGGATAACAATTTCACACAGGAAACAGCT
  ATGACCATTAGGCCTATTTAGGTGACACTATAGAACAAGTTTGTACAAAAAAGCAGGCTG
  GTACCGGTCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGGCAGGAAAGGCGCGGG
  AGGCGGGGGAGGTGCGGAGATGGCGCTCTGCACGGCGGCGGAGGGAGGGCGCTGGCGCCG
  GGGACACGAAACCGCAGAGCCCGGACGAGTCAGGGAGTGAGGCGCGAGCCGGGCGCCCGG
  GGCTCTGCAGGCGCAGGCGGCGCGGGGACAGGAGCAGGTTACCGGGCCGCCCGAGCGCTC
  GCACCCCGCTGAAAGAAACGCAGGCGGCCCGCCGGCTCTGCCTGGTCCGCTACCCGACCA
  GCTCCCGGCTCGGGGCTCAGAGCTAGGGGCTTACGCCAAGCGGAGCCCGGGGGAGGGGTG
  CCCAACTCTCTCCGCCGGAACCCAAGCCGGGACTCATTGATGCGCTGGCGGCGTGCGGCC
  GGGAACTCCGGGGTAGATGACCGCGGAATGAGCCATGATCATTGATTACTGTCTCTTTGT
  ACATAGTACGTGTAAAACTGCATCACCAATGGTAAAAAGTACCGTCAACAGAAAG
• Restriction Sites: Please inquire
• ACCN: NM_182665
• ORF Size: 798 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_182665.2, NP_872606.1
• RefSeq Size: 3531
• RefSeq ORF: 798
• Locus ID: 83593
• Protein Families: Druggable Genome
• Protein Pathways: Leukocyte transendothelial migration, Non-small cell lung cancer, Pathways in cancer
• Gene Summary: This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3), also known as transcript B, differs in the 5' UTR, lacks a portion of the 5' coding region, and intiates translation at an alternate start codon, compared to variant 1. The resulting isoform (C), also known as NORE1B, is shorter and has a distinct N-terminus when compared to isoform A.