ARFGAP3 (NM_014570) Human Untagged Clone

CAT#: SC324381

ARFGAP3 (untagged)-Human ADP-ribosylation factor GTPase activating protein 3 (ARFGAP3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARFGAP3
• Synonyms: ARFGAP1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014570.3 GCCAGCTGCGCCGCGGCTCACAGCTGACGATGGGGGACCCCAGCAAGCAGGACATCTTGA
  CCATCTTCAAGCGCCTCCGCTCGGTGCCCACTAACAAGGTGTGTTTTGATTGTGGTGCCA
  AAAATCCCAGCTGGGCAAGCATAACCTATGGAGTGTTCCTTTGCATTGATTGCTCAGGGT
  CCCACCGGTCACTTGGTGTTCACTTGAGTTTTATTCGATCTACAGAGTTGGATTCCAACT
  GGTCATGGTTTCAGTTGCGATGCATGCAAGTCGGAGGAAACGCTAGTGCATCTTCCTTTT
  TTCATCAACATGGGTGTTCCACCAATGACACCAATGCCAAGTACAACAGTCGTGCTGCTC
  AGCTCTATAGGGAGAAAATCAAATCGCTCGCCTCTCAAGCAACACGGAAGCATGGCACTG
  ATCTGTGGCTTGATAGTTGTGTGGTTCCACCTTTGTCCCCTCCACCAAAGGAGGAAGATT
  TTTTTGCCTCTCACGTTTCTCCTGAGGTGAGTGACACAGCGTGGGCATCAGCAATAGCAG
  AACCATCTTCTTTAACATCAAGGCCTGTGGAAACCACTTTGGAAAATAATGAAGGTGGAC
  AAGAGCAAGGACCAAGTGTGGAAGGTCTTAATGTACCAACAAAGGCTACTTTAGAGGTAT
  CCTCTATCATAAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAA
  GTTTGGGAGCTCAGAAACTGGCAAACACATGCTTTAATGAAATTGAAAAACAAGCTCAAG
  CTGCGGATAAAATGAAGGAGCAGGAAGACCTGGCCAAGGTGGTATCTAAAGAAGAATCAA
  TTGTTTCATCATTACGATTAGCCTATAAGGATCTTGAAATTCAAATGAAGAAAGACGAAA
  AGATGAACATTAGTGGCAAAAAAAATGTTGACTCAGACAGACTCGGCATGGGATTTGGAA
  ATTGCAGAAGTGTTATTTCACATTCAGTGACTTCAGATATGCAGACCATAGAGCAGGAAT
  CACCCATTATGGCAAAACCAAGAAAAAAGTATAATGATGACAGTGACGATTCATATTTTA
  CTTCCAGCTCAAGGTACTTTGACGAGCCAGTGGAGTTAAGGAGCAGTTCTTTCTCTAGCT
  GGGATGACAGTTCAGATTCCTATTGGAAAAAAGAGACCAGCAAAGATACTGAAACAGTTC
  TGAAAACCACAGGCTATTCAGACAGACCTACTGCTCGCCGCAAGCCAGATTATGAGCCAG
  TTGAAAATACAGATGAGGCCCAGAAGAAGTTTGGCAATGTCAAGGCCATTTCATCAGATA
  TGTATTTTGGAAGACAATCCCAGGCTGATTATGAGACCAGGGCCCGCCTAGAGAGGCTGT
  CAGCAAGTTCCTCCATAAGCTCGGCTGATCTGTTCGAGGAGCCGAGGAAGCAGCCAGCAG
  GGAACTACAGCCTGTCCAGCGTGCTGCCCAACGCCCCCGACATGGCGCAGTTCAAGCAGG
  GAGTGAGATCGGTTGCTGGAAAACTCTCCGTCTTTGCTAATGGAGTCGTGACTTCAATTC
  AGGATCGCTACGGTTCTTAATACTGAAGTCATGATGTGTATTTCCTGGAGAAATTCCTCT
  TTAAATGAACAAGTAACCACATCTCAGGCGGCAGTGAAGTCCAGATAGTTTTGCAGATTG
  TTTTGCTACTTTTTCATATGGTATATGTTTCTGATTTTTAATATTTCTTTTGAGAAATTC
  TGAGTTCTGATGTAGGAGCTTTCCTGTGATTTCTGTTTCACGTTCCTTCCTGTCACACCC
  TCCTTTGGCGTCTCTGTGTATATCCTTGCTTTATTTTCTTGGAACCTTTGGTTTCAACAC
  TGAGGGCCTGGAGACCTCGGCTCCTCCTGCTCCTGAACCAGGAGGCTTCATGTGGGGGAG
  GAGGAGAGGTCTCCATGTGACACATGGGCTCAGGGCTGCCAGAATCAGCGGATGCTGGAT
  GGGCCTGCAGAAACAACACTCACCACACACACTTCCTTCAAAAGACCAAAAGTGACTGGT
  GTCTCGTGTGACAGATTGCTTCATTTATGTTTCTACATAGTAAGGTGACTGCCAAATAAT
  ATTTGAAGTCATCTGTCTCTTTGTAAATTATTTTATATGACCTATAAATTTAAAAATGTT
  TTTCAGTGAGTGCTTTTAACAAACTTAAGCTTCTGCCCTGCCAAGGGAATTAATGTTATC
  TTGTGAAAGGTGTTGCTGTTTGAATTGATGAGAAATGGAAGATGAGAACTCCCTAAGAGT
  TCTCATAATAAATCATCTCATCACAAATCAATACGGTATACAGAGTTAAAGTGGAATGAG
  GTAAGAAGATACAGCTACAGAAAATAGTTGCGTGTATGGGAGAACAGTCATTGTAATTGG
  GTAGTTTTGTTAATAAATATTTTTAAATCTTGCTTTTCAGAAATTACCGAATGTGTATAA
  ACAAATAAAGAAAAATAATTTAGCTGTGTTTTAGACAGCATTAGAATATATTGTTCAGCA
  CAGTAAAATATATTTGAAATTTGATAAGCCAAAAATGTGGTTTTGAATGAATATTTTGTG
  AATCTTTCTTAAAAGCTCAAATTTGTAGACTTCTAAATAGAATAAACACTTGCAGCAGAA
  AAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014570.3 unedited
  GGGCGTTTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGCCAGCTGCG
  CCGCGGCTCACAGCTGACGATGGGGGACCCCAGCAAGCAGGACATCTTGACCATCTTCAA
  GCGCCTCCGCTCGGTGCCCACTAACAAGGTGTGTTTTGATTGTGGTGCCAAAAATCCCAG
  CTGGGCAAGCATAACCTATGGAGTGTTCCTTTGCATTGATTGCTCAGGGTCCCACCGGTC
  ACTTGGTGTTCACTTGAGTTTTATTCGATCTACAGAGTTGGATTCCAACTGGTCATGGTT
  TCAGTTGCGATGCATGCAAGTCGGAGGAAACGCTAGTGCATCTTCCTTTTTTCATCAACA
  TGGGTGTTCCACCAATGACACCAATGCCAAGTACAACAGTCGTGCTGCTCAGCTCTATAG
  GGAGAAAATCAAATCGCTCGCCTCTCAAGCAACACGGAAGCATGGCACTGATCTGTGGCT
  TGATAGTTGTGTGGTTCCACCTTTGTCCCCTCCACCAAAGGAGGAAGATTTTTTTGCCTC
  TCACGTTTCTCCTGAGGTGAGTGACACAGCGTGGGCATCAGCAATAGCAGAACCATCTTC
  TTTAACATCAAGGCCTGTGGAAACCACTTTGGAAAATAATGAAGGTGGACAAGAGCAAGG
  ACCAAGTGTGGAAAGGTCTTATGTACCAACAAAGGCTACTTTAGAGGTATCCTCTATCAT
  AAAAAAGAAACCAAATCAAGCTAAAAAAGGCCTTGGGGCCAAAAAAGGAAGTTTGGGAGC
  TCAGAAACTGGCAAACACATGCTTTATGAAATTGAAAAACAAGCTCAAGCTGCGATAAAA
  TGATGGAGCAGAGACCTGCCAGGTGGTATCTAGGAGATCATTGTTCATCATTACGATTAG
  CCTATATAGGATCTTGAATTCAAATGAGG
• Restriction Sites: Please inquire
• ACCN: NM_014570
• ORF Size: 1551 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014570.3, NP_055385.2
• RefSeq Size: 2725
• RefSeq ORF: 1551
• Locus ID: 26286
• Domains: ArfGap
• Protein Pathways: Endocytosis
• Gene Summary: The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).