FBXL14 (NM_152441) Human Untagged Clone

CAT#: SC324683

FBXL14 (untagged)-Human F-box and leucine-rich repeat protein 14 (FBXL14)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBXL14
• Synonyms: Fbl14
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_152441.1 GGCGGCGGCTGGGGAGAAGCGCTCTCGTCGCCTGCCCGAGGCCGGAGCGGCGGGGCCCGC
  GCCTCCTCCCCCCAGCGCCGCGGAGGGGGGAGGAGGAAGATGGAGACCCACATCTCATGC
  CTGTTCCCGGAGCTGCTGGCCATGATCTTCGGCTACCTGGACGTCCGGGACAAGGGGCGC
  GCGGCGCAGGTGTGCACCGCCTGGCGGGACGCCGCCTACCACAAGTCGGTGTGGCGGGGG
  GTGGAGGCCAAGCTGCACCTGCGCCGGGCCAACCCGTCGCTGTTCCCCAGCCTGCAGGCC
  CGGGGCATCCGCCGGGTGCAGATCCTGAGCCTCCGCCGCAGCCTCAGCTACGTGATCCAG
  GGCATGGCCAACATCGAGAGCCTCAACCTCAGCGGCTGCTACAACCTCACCGACAACGGG
  CTGGGCCACGCGTTTGTGCAGGAGATCGGCTCCCTGCGCGCTCTCAACCTGAGCCTCTGC
  AAGCAGATCACTGACAGCAGCCTGGGCCGCATAGCCCAGTACCTCAAGGGCCTGGAGGTG
  CTGGAGCTGGGAGGTTGCAGCAACATCACCAACACTGGCCTTCTGCTCATCGCCTGGGGT
  CTGCAGCGCCTCAAGAGCCTTAACCTCCGCAGCTGCCGCCACCTTTCGGATGTGGGCATC
  GGGCACCTGGCCGGCATGACGCGCAGCGCGGCGGAGGGCTGCCTGGGCCTGGAGCAGCTC
  ACGCTACAGGACTGCCAGAAGCTCACAGATCTTTCTCTAAAGCACATCTCCCGAGGGCTG
  ACGGGCTTGAGGCTCCTCAACCTCAGCTTCTGTGGGGGAATCTCGGACGCTGGCCTCCTG
  CACCTGTCGCACATGGGCAGCCTGCGCAGCCTCAACCTGCGCTCCTGTGACAACATCAGT
  GACACGGGCATCATGCATCTGGCCATGGGCAGCCTGCGCCTCTCGGGGCTGGATGTTTCG
  TTCTGTGACAAGGTGGGAGACCAGAGTCTGGCTTACATAGCCCAGGGGCTGGATGGCCTC
  AAGTCTCTCTCCCTCTGCTCCTGCCACATCAGTGATGATGGCATCAACCGCATGGTGCGG
  CAGATGCACGGGCTGCGCACGCTCAACATTGGACAGTGTGTGCGCATCACGGACAAGGGC
  CTGGAGCTGATCGCTGAGCACCTGAGCCAACTCACCGGCATAGACCTGTACGGCTGCACC
  CGAATCACCAAGCGCGGCCTGGAGCGCATCACGCAGCTGCCGTGCCTCAAGGTACTCAAC
  CTGGGACTCTGGCAGATGACGGACAGTGAGAAGGAGGCACGAGGGGATTTTTCTCCATTA
  TTCACTGTGAGAACTCGGGGAAGCTCCAGAAGGTGAGGGAGAGGGGACAACGACATGGTT
  CCCGTGGATCTTTAACTTCCAGACTTGCCCGCTCTGCGCCTCCGGCACTCTGGTGATGAC
  AGCTCAGGTTTCCCTGCCTGTCACTGCTCGGGCAGAGGCTGCTGCCCAGGGCTTCTGCTC
  CGGTACCTTGTGAAGCTGCATTCTCCTGCCGGTTTCTCCAGTTCTGGGGACAGTGGTTTG
  CTCTGAGACCTCGCTTCCTTTATGGATCCAAGGAGACTTGCTTTTTCAGTCTGTTCAGCT
  TTTTACTTGCTAGGATGGAATTGCAATTTGCAAGCTTCTTCGACAGGAAACTACAAGTTC
  CACACTTTAATTTTATACATATAAATATATACATGTACATATATCTATGTACAGGGGTAT
  TATATATATACATATAAGATGATGATATATATAATGATGATATGTATTACTGAGAACGTA
  AAATATCATTACATAGTGATAGCTGGACACACAAGGAATTCACAACTCCCCAAAGAAAAT
  ACATCTGGATGACCTGCCTAGCAGTTTCCCCATGAGATAGAGGAATGTCTACGTATTTCA
  TTCCCTGTTCCTGCCCTGAAACAATTTCAATCACTGACAAATCATTATCATTCATTAATA
  ATGTTTACTGAGTGCCCATATGTGAAAGAAATCCACTCTACATTCCACAGATGCATTTCC
  TCTCCCCACGGGGTTTCCATTTTAATGGGAACAATGTAGAATATATCTGTCTTCCCTTTA
  TAGATTCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152441.1 unedited
  TACATCTGCTGTAAACGAACTTCCCACTAGGGCGGCCGGCGACTCGCGGCGCGCCGGTAC
  CGGTCCGGAATTCCCGGGTATGGCGGCGGCTGGGGAGAAGCGCTCTCGTCGCCTGCCCGA
  GGCCGGAGCGGCGGGGCCCGCGCCTCCTCCCCCCAGCGCCGCGGAGGGGGGAGGAGGAAG
  ATGGAGACCCACATCTCATGCCTGTTCCCGGAGCTGCTGGCCATGATCTTCGGCTACCTG
  GACGTCCGGGACAAGGGGCGCGCGGCGCAGGTGTGCACCGCCTGTTTTTATTCCGCCTAC
  CACAAGTCGGTGCGGATTTCCGTGCAACCCCCACAGCCCATACCACAAAGAAAAACAAAC
  ACCCCCCCCCCTTTTTTTTTCTAAAATTTTTTTTTACCCCACCCCCTTTTATAAATGGGT
  CTATTTGCGGCGTCCCTGCAGCGGGGGATATATTATACCCCCCCCTGCCCTTTATTACCC
  CCCCCACCAAAAACCCCCCCTAAAC
• Restriction Sites: Please inquire
• ACCN: NM_152441
• ORF Size: 1257 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_152441.1, NP_689654.1
• RefSeq Size: 2164
• RefSeq ORF: 1257
• Locus ID: 144699
• Domains: LRR, F-box, LRR_CC
• Protein Families: Druggable Genome
• Gene Summary: Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]). [supplied by OMIM, Mar 2008]