CPSF7 (NM_001142565) Human Untagged Clone

CAT#: SC325961

CPSF7 (untagged)-Human cleavage and polyadenylation specific factor 7, 59kDa (CPSF7), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CPSF7
• Synonyms: CFIm59
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001142565, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCAGAAGGAGTGGACTTGATTGATATATATGCTGACGAGGAGTTCAACCAGGACCCAGAGTTCAACA
  ATACAGATCAGATTGACCTGTATGATGATGTGCTGACAGCCACCTCACAGCCCTCAGATGACAGAAGCAG
  CAGCACTGAACCACCTCCTCCTGTTCGCCAGGAGCCATCTCCCAAGCCCAACAACAAGACCCCTGCAATT
  CTGTATACCTACAGTGGCCTGCGTAATAGACGAGCTGCCGTTTATGTGGGCAGCTTCTCCTGGTGGACCA
  CAGACCAGCAGCTGATCCAGGTTATTCGCTCTATAGGAGTCTATGATGTGGTGGAGTTGAAATTTGCAGA
  GAATCGAGCAAATGGCCAGTCCAAAGGGTATGCTGAGGTGGTGGTAGCCTCTGAAAACTCTGTCCACAAA
  TTGTTGGAACTCCTACCAGGGAAAGTTCTTAATGGAGAAAAAGTGGACGTGAGGCCGGCCACCCGGCAGA
  ACCTGTCACAGTTTGAGGCACAGGCTCGGAAACGAATACCTCCACGGGCCCATTCCCGAGATTCTAGTGA
  TTCTGCTGATGGACGGGCCACACCCTCTGAGAACCTTGTACCCTCATCTGCTCGTGTGGATAAGCCCCCC
  AGTGTGCTGCCCTACTTCAATCGTCCTCCTTCGGCCCTTCCCCTGATGGGTCTGCCCCCACCACCAATTC
  CACCCCCACCACCTCTCTCCTCAAGCTTTGGGGTCCCTCCTCCTCCTCCTGGTATCCACTACCAGCATCT
  CATGCCCCCACCTCCTCGATTACCTCCTCATCTTGCTGTACCTCCCCCTGGGGCCATCCCACCTGCCCTT
  CACCTCAATCCAGCCTTCTTCCCCCCACCAAACGCTACAGTGGGGCCTCCACCAGATACTTACATGAAGG
  CCTCTGCCCCCTATAACCACCATGGCAGCCGAGATTCGGGCCCTCCACCCTCTACAGTGAGTGAAGCCGA
  ATTTGAAGATATCATGAAGCGAAACAGAGCAATTTCCAGCAGTGCCATTTCCAAAGCAGTATCTGGAGCC
  AGTGCAGGGGATTACAGTGACGCAATTGAGACGCTGCTCACAGCCATTGCGGTTATCAAACAGTCCCGGG
  TTGCCAATGATGAGCGTTGCCGTGTCCTCATCTCCTCTCTTAAGGACTGTCTTCATGGCATCGAAGCCAA
  GTCCTACAGTGTGGGTGCCAGTGGGAGCTCTTCCAGGAAAAGACATCGCTCCCGGGAAAGGTCACCTAGC
  CGGTCCCGGGAGAGCAGCAGGAGGCACCGGGATCTGCTTCATAATGAAGATCGGCATGATGATTATTTCC
  AAGAAAGGAACCGGGAGCATGAGAGACACCGGGATAGAGAACGGGACCGGCACCACTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001142565
• ORF Size: 1389 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001142565.1, NP_001136037.1
• RefSeq Size: 3661
• RefSeq ORF: 1389
• Locus ID: 79869
• Gene Summary: Cleavage factor Im (CFIm) is one of six factors necessary for correct cleavage and polyadenylation of pre-mRNAs. CFIm is composed of three different subunits of 25, 59, and 68 kDa, and it functions as a heterotetramer, with a dimer of the 25 kDa subunit binding to two of the 59 or 68 kDa subunits. The protein encoded by this gene represents the 59 kDa subunit, which can interact with the splicing factor U2 snRNP Auxiliary Factor (U2AF) 65 to link the splicing and polyadenylation complexes. [provided by RefSeq, Oct 2016]
  Transcript Variant: This variant (3) has an alternate 5' exon, which results in a downstream AUG start codon, and lacks an in-frame coding segment, as compared to variant 1. The resulting isoform (3) has a shorter N-terminus and lacks an internal segment, as compared to isoform 1.