MEF2A (NM_001130926) Human Untagged Clone

CAT#: SC325998

MEF2A (untagged)-Human myocyte enhancer factor 2A (MEF2A), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MEF2A
• Synonyms: ADCAD1; mef2; RSRFC4; RSRFC9
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001130926, the custom clone sequence may differ by one or more nucleotides
  ATGGGGCGGAAGAAAATACAAATCACACGCATAATGGATGAAAGGAACCGACAGGTCACT
  TTTACAAAGAGAAAGTTTGGATTAATGAAGAAAGCCTATGAACTTAGTGTGCTCTGTGAC
  TGTGAAATAGCACTCATCATTTTCAACAGCTCTAACAAACTGTTTCAATATGCTAGCACT
  GATATGGACAAAGTTCTTCTCAAGTATACAGAATATAATGAACCTCATGAAAGCAGAACC
  AACTCGGATATTGTTGAGACTTTAAGAAAGAAAGGCCTTAATGGTTGTGAGAGCCCTGAT
  GCTGACGATTACTTTGAGCACAGTCCACTCTCGGAGGACAGATTCAGCAAACTAAATGAA
  GATAGTGATTTTATTTTCAAACGAGGCCCTCCTGGTCTGCCACCTCAGAACTTTTCAATG
  TCTGTCACAGTTCCAGTGACCAGCCCCAATGCTTTGTCCTACACTAACCCAGGGAGTTCA
  CTGGTGTCCCCATCTTTGGCAGCCAGCTCAACGTTAACAGATTCAAGCATGCTCTCTCCA
  CCTCAAACCACATTACATAGAAATGTGTCTCCTGGAGCTCCTCAGAGACCACCAAGTACT
  GGCAATGCAGGTGGGATGTTGAGCACTACAGACCTCACAGTGCCAAATGGAGCTGGAAGC
  AGTCCAGTGGGGAATGGATTTGTAAACTCAAGAGCTTCTCCAAATTTGATTGGAGCTACT
  GGTGCAAATAGCTTAGGCAAAGTCATGCCTACAAAGTCTCCCCCTCCACCAGGTGGTGGT
  AATCTTGGAATGAACAGTAGGAAACCAGATCTTCGAGTTGTCATCCCCCCTTCAAGCAAG
  GGCATGATGCCTCCACTAAATACCCAAAGGATCAGTAGTTCTCAAGCCACTCAACCTCTT
  GCTACCCCAGTCGTGTCTGTGACAACCCCAAGCTTGCCTCCGCAAGGACTTGTGTACTCA
  GCAATGCCGACTGCCTACAACACTGATTATTCACTGACCAGCGCTGACCTGTCAGCCCTT
  CAAGGCTTCAACTCGCCAGGAATGCTGTCGCTGGGACAGGTGTCGGCCTGGCAGCAGCAC
  CACCTAGGACAAGCAGCCCTCAGCTCTCTTGTTGCTGGAGGGCAGTTATCTCAGGGTTCC
  AATTTATCCATTAATACCAACCAAAACATCAGCATCAAGTCCGAACCGATTTCACCTCCT
  CGGGATCGTATGACCCCATCGGGCTTCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAG
  CCGCCGCCACCACCGCAGCCCCAGCCACAACCCCCGCAGCCCCAGCCCCGACAGGAAATG
  GGGCGCTCCCCTGTGGACAGTCTGAGCAGCTCTAGTAGCTCCTATGATGGCAGTGATCGG
  GAGGATCCACGGGGCGACTTCCATTCTCCAATTGTGCTTGGCCGACCCCCAAACACTGAG
  GACAGAGAAAGCCCTTCTGTAAAGCGAATGAGGATGGACGCGTGGGTGACC
  
• Restriction Sites: Please inquire
• ACCN: NM_001130926
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001130926.1, NP_001124398.1
• RefSeq Size: 5481 bp
• RefSeq ORF: 1494 bp
• Locus ID: 4205
• Cytogenetics: 15q26.3
• Protein Families: Transcription Factors
• Gene Summary: 'The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]'
  Transcript Variant: This variant (2) lacks an in-frame coding exon and a 5' non-coding exon, compared to transcript variant 6. These differences result in a shorter isoform (2), compared to isoform 5. Variants 2 and 5 both encode isoform 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.