Apc7 (ANAPC7) (NM_001137664) Human Untagged Clone

CAT#: SC326044

ANAPC7 (untagged)-Human anaphase promoting complex subunit 7 (ANAPC7), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ANAPC7
• Synonyms: APC7
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001137664, the custom clone sequence may differ by one or more nucleotides
  ATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTC
  GAGTCAGTGCTGCCGCCGCTGCCCGCGGCTTTGCAGAGCAGGATGAATGTGATAGACCAC
  GTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTTA
  CTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTG
  GTGTATCATGCAGATTCTCTCTTTCATGATAAGGAATATCGGAATGCTGTGAGTAAGTAT
  ACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAACT
  GGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATAC
  AAAATGGCTGAATGTTATACAATGCTAAAACAAGATAAAGATGCCATTGCTATACTTGAT
  GGGATCCCTTCAAGACAAAGAACTCCCAAAATAAACATGATGCTGGCAAACCTGTACAAG
  AAGGCTGGTCAGGAGCGCCCTTCAGTCACCAGCTATAAGGAGGTGCTGAGGCAGTGCCCA
  TTAGCCCTTGATGCCATTCTAGGCTTGTTGTCCCTTTCTGTAAAAGGGGCAGAGGTGGCA
  TCCATGACAATGAATGTGATCCAAACCGTGCCTAACTTGGACTGGCTCTCTGTGTGGATC
  AAAGCGTATGCTTTTGTGCACACTGGTGACAACTCAAGAGCAATCAGTACCATCTGTTCA
  CTAGAGAAAAAATCCTTATTGCGAGATAACGTGGACCTATTGGGAAGCTTGGCAGATCTG
  TACTTCAGAGCTGGAGACAATAAAAACTCTGTCCTCAAGTTTGAACAGGCACAGATGTTG
  GATCCTTATCTGATAAAAGGAATGGATGTATATGGCTACCTACTGGCACGAGAAGGGCGG
  CTAGAGGATGTTGAGAACCTTGGATGCCGCCTTTTCAATATCTCTGATCAGCATGCAGAA
  CCGTGGGTGGTTTCTGGCTGTCACAGCTTCTATAGCAAACGCTACTCCCGGGCCCTCTAT
  TTAGGAGCCAAGGCCATTCAGCTGAACAGTAATAGTGTTCAAGCTCTGCTACTTAAGGGA
  GCAGCACTTAGGAACATGGGCAGAGTCCAAGAAGCAATAATCCACTTTCGGGAGGCCATA
  CGGCTCGCACCTTGTCGCTTAGATTGTTATGAAGGTCTTATCGAATGTTACTTAGCCTCC
  AACAGTATTCGAGAAGCAATGGTAATGGCTAACAACGTTTACAAAACTCTGGGAGCAAAT
  GCACAGACCCTTACCCTTTTAGCCACCGTTTGTCTTGAAGACCCAGTGACACAGGAGAAA
  GCCAAAACATTATTAGATAAAGCCCTGACCCAAAGGCCAGATTACATTAAGGCTGTGGTG
  AAAAAAGCAGAACTACTTAGCAGAGAACAGAAATATGAAGATGGAATTGCTTTGCTGAGG
  AACGCACTGGCTAATCAGAGTGACTGTGTCCTGCATCGGATCCTAGGAGATTTCCTTGTA
  GCTGTCAATGAGTATCAGGAGGCAATGGACCAGTATAGTATAGCACTAAGG
  
• Restriction Sites: Please inquire
• ACCN: NM_001137664
• ORF Size: 1614 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001137664.1, NP_001131136.1
• RefSeq Size: 2224
• RefSeq ORF: 1614
• Locus ID: 51434
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
  Transcript Variant: This variant (2) differs in the 3' UTR and 3' coding region (compared to variant 1), which results in a frameshift. It encodes isoform b which has a shorter and distinct C-terminus compared to isoform a.