NCOA4 (NM_001145261) Human Untagged Clone

CAT#: SC326123

NCOA4 (untagged)-Human nuclear receptor coactivator 4 (NCOA4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NCOA4
• Synonyms: ARA70; ELE1; PTC3; RFG
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001145261, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGGCCCAGTTGACCACTTTTGCTCTAGCTGGAGCAGTGAGGAGAATGAATACCTTCCAAGACCAGA
  GTGGCAGCTCCAGTAATAGAGAACCCCTTTTGAGGTGTAGTGATGCACGGAGGGACTTGGAGCTTGCTAT
  TGGTGGAGTTCTCCGGGCTGAACAGCAAATTAAAGATAACTTGCGAGAGGTCAAAGCTCAGATTCACAGT
  TGCATAAGCCGTCACCTGGAATGTCTTAGAAGCCGTGAGGTATGGCTGTATGAACAGGTGGACCTTATTT
  ATCAGCTTAAAGAGGAGACACTTCAACAGCAGGCTCAGCAGCTCTACTCGTTATTGGGCCAGTTCAATTG
  TCTTACTCATCAACTGGAGTGTACCCAAAACAAAGATCTAGCCAATCAAGTCTCTGTGTGCCTGGAGAGA
  CTGGGCAGTTTGACCCTTAAGCCTGAAGATTCAACTGTCCTGCTCTTTGAAGCTGACACAATTACTCTGC
  GCCAGACCATCACCACATTTGGGTCTCTCAAAACCATTCAAATTCCTGAGCACTTGATGGCTCATGCTAG
  TTCAGCAAATATTGGGCCCTTCCTGGAGAAGAGAGGCTGTATCTCCATGCCAGAGCAGAAGTCAGCATCC
  GGTATTGTAGCTGTCCCTTTCAGCGAATGGCTCCTTGGAAGCAAACCTGCCAGTGGTTATCAAGCTCCTT
  ACATACCCAGCACCGACCCCCAGGACTGGCTTACCCAAAAGCAGACCTTGGAGAACAGTCAGACTTCTTC
  CAGAGCCTGCAATTTCTTCAATAATGTCGGGGGAAACCTAAAGGGCTTAGAAAACTGGCTCCTCAAGAGT
  GAAAAATCAAGTTATCAAAAGTGTAACAGCCATTCCACTACTAGTTCTTTCTCCATTGAAATGGAAAAGG
  TTGGAGATCAAGAGCTTCCTGATCAAGATGAGATGGACCTATCAGATTGGCTAGTGACTCCCCAGGAATC
  CCATAAGCTGCGGAAGCCTGAGAATGGCAGTCGTGAAACCAGTGAGAAGTTTAAGCTCTTATTCCAGTCC
  TATAATGTGAATGATTGGCTTGTCAAGACTGACTCCTGTACCAACTGTCAGGGAAACCAGCCCAAAGGTG
  TGGAGATTGAAAACCTGGGCAATCTGAAGTGCCTGAATGACCACTTGGAGGCCAAGAAACCATTGTCCAC
  CCCCAGCATGGTTACAGAGGATTGGCTTGTCCAGAACCATCAGGACCCATGTAAGGTAGAGGAGGTGTGC
  AGAGCCAATGAGCCCTGCACAAGCTTTGCAGAGTGTGTGTGTGATGAGAATTGTGAGAAGGAGGCTCTGT
  ATAAGTGGCTTCTGAAGAAAGAAGGAAAGGATAAAAATGGGATGCCTGTGGAACCCAAACCTGAGCCTGA
  GAAGCATAAAGATTCCCTGAATATGTGGCTCTGTCCTAGAAAAGAAGTAATAGAACAAACTAAAGCACCA
  AAGGCAATGACTCCTTCTAGAATTGCTGATTCCTTCCAAGTCATAAAGAACAGCCCCTTGTCGGAGTGGC
  TTATCAGGCCCCCATACAAAGAAGGAAGTCCCAAGGAAGTGCCTGGTACTGAAGACAGAGCTGGCAAACA
  GAAGTTTAAAAGCCCCATGAATACTTCCTGGTGTTCCTTTAACACAGCTGACTGGGTCCTGCCAGGAAAG
  AAGATGGGCAACCTCAGCCAGTTATCTTCTGGAGAAGACAAGTGGCTGCTTCGAAAGAAGGCCCAGGAAG
  TATTACTTAATTCACCTCTACAGGAGGAACATAACTTCCCCCCAGACCATTATGGCCTCCCTGCAGTTTG
  TGATCTCTTTGCCTGTATGCAGCTTAAAGTTGATAAAGAGAAGTGGTTATATCGAACTCCTCTACAGATG
  TGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001145261
• ORF Size: 1893 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001145261.1, NP_001138733.1
• RefSeq Size: 3659
• RefSeq ORF: 1893
• Locus ID: 8031
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Pathways in cancer, Thyroid cancer
• Gene Summary: This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. [provided by RefSeq, Feb 2009]
  Transcript Variant: This variant (2) lacks an exon in the coding region, which results in a frameshift and use of a downstream stop codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1.