Leukotriene B4 Receptor 2 (LTB4R2) (NM_001164692) Human Untagged Clone

CAT#: SC326922

LTB4R2 (untagged)-Human leukotriene B4 receptor 2 (LTB4R2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LTB4R2
• Synonyms: BLT2; BLTR2; JULF2; KPG_004; LTB4-R 2; LTB4-R2; NOP9
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001164692, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCGGTCTGCTACCGTCCCCCAGGGAACGAGACACTGCTGAGCTGGAAGACTTCGCGGGCCACAGGCA
  CAGCCTTCCTGCTGCTGGCGGCGCTGCTGGGGCTGCCTGGCAACGGCTTCGTGGTGTGGAGCTTGGCGGG
  CTGGCGGCCTGCACGGGGGCGACCGCTGGCGGCCACGCTTGTGCTGCACCTGGCGCTGGCCGACGGCGCG
  GTGCTGCTGCTCACGCCGCTCTTTGTGGCCTTCCTGACCCGGCAGGCCTGGCCGCTGGGCCAGGCGGGCT
  GCAAGGCGGTGTACTACGTGTGCGCGCTCAGCATGTACGCCAGCGTGCTGCTCACCGGCCTGCTCAGCCT
  GCAGCGCTGCCTCGCAGTCACCCGCCCCTTCCTGGCGCCTCGGCTGCGCAGCCCGGCCCTGGCCCGCCGC
  CTGCTGCTGGCGGTCTGGCTGGCCGCCCTGTTGCTCGCCGTCCCGGCCGCCGTCTACCGCCACCTGTGGA
  GGGACCGCGTATGCCAGCTGTGCCACCCGTCGCCGGTCCACGCCGCCGCCCACCTGAGCCTGGAGACTCT
  GACCGCTTTCGTGCTTCCTTTCGGGCTGATGCTCGGCTGCTACAGCGTGACGCTGGCACGGCTGCGGGGC
  GCCCGCTGGGGCTCCGGGCGGCACGGGGCGCGGGTGGGCCGGCTGGTGAGCGCCATCGTGCTTGCCTTCG
  GCTTGCTCTGGGCCCCCTACCACGCAGTCAACCTTCTGCAGGCGGTCGCAGCGCTGGCTCCACCGGAAGG
  GGCCTTGGCGAAGCTGGGCGGAGCCGGCCAGGCGGCGCGAGCGGGAACTACGGCCTTGGCCTTCTTCAGT
  TCTAGCGTCAACCCGGTGCTCTACGTCTTCACCGCTGGAGATCTGCTGCCCCGGGCAGGTCCCCGTTTCC
  TCACGCGGCTCTTCGAAGGCTCTGGGGAGGCCCGAGGGGGCGGCCGCTCTAGGGAAGGGACCATGGAGCT
  CCGAACTACCCCTCAGCTGAAAGTGGTGGGGCAGGGCCGCGGCAATGGAGACCCGGGGGGTGGGATGGAG
  AAGGACGGTCCGGAATGGGACCTTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001164692
• ORF Size: 1077 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001164692.2, NP_001158164.1
• RefSeq Size: 1560
• RefSeq ORF: 1077
• Locus ID: 56413
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) represents the longer transcript. Both variants 1 and 2 encode the same protein.