MGAT4A (NM_001160154) Human Untagged Clone

CAT#: SC326975

MGAT4A (untagged)-Human mannosyl (alpha-13-)-glycoprotein beta-14-N-acetylglucosaminyltransferase isozyme A (MGAT4A) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MGAT4A
• Synonyms: GnT-4a; GNT-IV; GNT-IVA
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001160154, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAATTACAGTATTACAGTTTCAATAGTCATGGGCATTCCCACAGTGAAGAGAGAAGTTAAATCTTACC
  TCATAGAAACTCTTCATTCCCTTATTGATAACCTGTATCCTGAAGAGAAGTTGGACTGTGTTATAGTAGT
  CTTCATAGGAGAGACAGATATTGATTATGTACATGGTGTTGTAGCCAACCTGGAGAAAGAATTTTCTAAA
  GAAATCAGTTCTGGCTTGGTGGAAGTCATATCACCCCCTGAAAGCTATTATCCTGACTTGACAAACCTAA
  AGGAGACATTTGGAGACTCCAAAGAAAGAGTAAGATGGAGAACAAAGCAAAACCTAGATTACTGTTTTCT
  AATGATGTATGCTCAAGAAAAGGGCATATATTACATTCAGCTTGAAGATGATATTATTGTCAAACAAAAT
  TATTTTAATACCATAAAAAATTTTGCACTTCAACTTTCTTCTGAGGAATGGATGATTCTAGAGTTTTCCC
  AGCTGGGCTTCATTGGTAAAATGTTTCAAGCGCCGGATCTTACTCTGATTGTAGAATTCATATTCATGTT
  TTACAAGGAGAAACCCATTGATTGGCTCCTGGACCATATTCTCTGGGTGAAAGTCTGCAACCCTGAAAAA
  GATGCAAAACATTGTGATAGACAGAAAGCAAATCTGCGAATTCGCTTCAGACCTTCCCTTTTCCAACATG
  TTGGTCTGCACTCATCACTATCAGGAAAAATCCAAAAACTCACGGATAAAGATTATATGAAACCATTACT
  TCTTAAAATCCATGTAAACCCACCTGCGGAGGTATCTACTTCCTTGAAGGTCTACCAAGGGCATACGCTG
  GAGAAAACTTACATGGGAGAGGATTTCTTCTGGGCTATCACACCGATAGCTGGAGACTACATCTTGTTTA
  AATTTGATAAACCAGTCAATGTAGAAAGTTATTTGTTCCATAGCGGCAACCAAGAACATCCTGGAGATAT
  TCTGCTAAACACAACTGTGGAAGTTTTGCCTTTTAAGAGTGAAGGTTTGGAAATAAGCAAAGAAACCAAA
  GACAAACGATTAGAAGATGGCTATTTCAGAATAGGAAAATTTGAGAATGGTGTTGCAGAAGGAATGGTGG
  ATCCAAGTCTCAATCCCATTTCAGCCTTTCGACTTTCAGTTATTCAGAATTCTGCTGTTTGGGCCATTCT
  TAATGAGCAGAGAGTTTTCTCGGGCTGGTGGCAGAAGTCAAGAGACAAAGCAGAAGGACCTCAGGCACCA
  TTGCTGTTTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001160154
• ORF Size: 1272 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001160154.1, NP_001153626.1
• RefSeq Size: 3726
• RefSeq ORF: 1272
• Locus ID: 11320
• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis
• Gene Summary: This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) represents use of an alternate promoter and 5' UTR, and lacks an alternate segment in the 3' coding region, compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus, and a longer and distinct C-terminus, compared to isoform 1.