DISC1 (NM_001164546) Human Untagged Clone

CAT#: SC327088

DISC1 (untagged)-Human disrupted in schizophrenia 1 (DISC1) transcript variant i

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DISC1
• Synonyms: C1orf136; SCZD9
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001164546, the custom clone sequence may differ by one or more nucleotides
  ATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCGCCGGCGGCGGCGGCGTGAGCCAC
  CGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCA
  CGGAGGCCGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCA
  GTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTGGCGAGGAGTCCCACCACTCGGAG
  TCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCC
  AAGAGTGCAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATT
  CAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTAGCTGGCCGTGTGGCCCTGGGAGT
  GCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGG
  GAGGCAGCCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCA
  GAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCCCTGAGGTCCCCCCAACCCCTCCT
  GGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCC
  GGGGAACGTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAG
  AGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGGACGGGCCTCACGAGGACCCGCGA
  TGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGCCCAGGCC
  GCAAGGAACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGACCCTGGC
  TCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTGGTGGTGATGGGAGCAGCGGCTCA
  GGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCGGGACTGC
  CTGCTGAGAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCAGAAACTT
  CAGGAAGATGCAGTTGAGAATGATGATTATGATAAAGCTGAGACGTTACAACAAAGATTA
  GAAGACCTGGAACAAGAGAAAATCAGCCTGCACTTTCAACTTCCTTCAAGGCAGCCAGCT
  CTTAGCAGTTTCCTGGGTCACCTGGCAGCACAAGTCCAGGCTGCCTTGCGCCGTGGGGCC
  ACTCAGCAGGCCAGCGGAGATGACACCCACACCCCACTGAGAATGGAGCCGAGGCTGTTG
  GAACCCACTGCTCAGGACAGCTTGCACGTGTCCATCACGAGACGAGACTGGCTTCTTCAG
  GAAAAGCAGCAGCTACAGAAAGAAATCGAAGCTCTCCAAGCAAGGATGTTTGTGCTGGAA
  GCCAAAGATCAACAGCTGAGAAGGGAAATAGAGGAGCAAGAGCAGCAACTCCAGTGGCAG
  GGCTGCGACCTGACCCCACTGGTGGGCCAGCTGTCCCTGGGTCAGCTGCAGGAGGTCAGC
  AAGGCCTTGCAGGACACCCTGGCCTCAGCCGGTCAGATTCCCTTCCATGCAGAGCCACCG
  GAAACCATAAGGAGAAACAAGTGTGAAGGAAAATACTATGAAGTACATGGAAACACT
  
• Restriction Sites: Please inquire
• ACCN: NM_001164546
• ORF Size: 1680 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001164546.1, NP_001158018.1
• RefSeq Size: 2363
• RefSeq ORF: 1680
• Locus ID: 27185
• Gene Summary: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (i) lacks three internal exons and three 3' exons but has an alternate 3' segment, as compared to variant L. Variants i and j encode the same isoform (i), which is much shorter and has a distinct C-terminus, as compared to isoform L.