Filamin B (FLNB) (NM_001164318) Human Untagged Clone
CAT#: SC327346
FLNB (untagged)-Human filamin B beta (FLNB) transcript variant 3
"NM_001164318" in other vectors (2)
Product Images
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Other products for "FLNB"
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | FLNB |
Synonyms | ABP-278; ABP-280; AOI; FH1; FLN-B; FLN1L; LRS1; SCT; TABP; TAP |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_001164318, the custom clone sequence may differ by one or more nucleotides
ATGCCGGTAACCGAGAAGGATCTAGCTGAGGACGCGCCTTGGAAGAAGATCCAGCAGAAC ACGTTCACACGCTGGTGCAACGAGCACCTCAAGTGCGTGAACAAACGCATCGGCAACCTG CAGACCGACCTGAGCGACGGGCTGCGGCTCATCGCGCTGCTCGAGGTGCTCAGCCAGAAG CGCATGTACCGCAAGTACCATCAGCGGCCCACCTTTCGCCAGATGCAGCTCGAGAATGTG TCCGTGGCGCTCGAGTTCCTGGACCGTGAGAGCATCAAGCTCGTGTCCATCGATAGCAAA GCCATTGTGGATGGGAACCTGAAGCTCATCTTGGGTCTGGTGTGGACGCTGATCCTCCAC TACTCCATCTCCATGCCCGTGTGGGAGGATGAAGGGGATGATGATGCCAAGAAGCAGACG CCAAAGCAGAGGCTGCTGGGGTGGATTCAGAACAAGATCCCCTACTTGCCCATCACCAAC TTTAACCAGAACTGGCAAGACGGCAAAGCCCTGGGAGCCCTGGTAGACAGCTGTGCTCCA GGTCTGTGCCCAGACTGGGAATCCTGGGACCCGCAGAAGCCTGTGGATAATGCACGAGAA GCCATGCAGCAGGCAGATGACTGGCTGGGTGTCCCACAGGTCATCACTCCTGAAGAAATC ATTCACCCGGATGTGGACGAGCACTCAGTTATGACTTACCTGTCCCAGTTCCCCAAAGCC AAGCTCAAGCCGGGGGCTCCTCTCAAACCCAAACTCAACCCGAAGAAAGCCAGGGCCTAT GGCAGAGGAATCGAGCCCACTGGAAACATGGTGAAGCAGCCAGCCAAGTTCACTGTGGAC ACCATCAGCGCCGGGCAAGGAGACGTGATGGTGTTTGTTGAGGACCCAGAAGGGAACAAA GAGGAGGCACAAGTGACCCCTGACAGTGACAAGAACAAGACATACTCTGTGGAGTATCTG CCCAAGGTCACCGGGCTACACAAAGTCACAGTCCTCTTTGCAGGACAGCACATCTCCAAG AGCCCATTTGAAGTGAGTGTTGACAAGGCCCAGGGAGATGCCAGTAAAGTCACTGCAAAA GGTCCAGGGTTGGAAGCTGTAGGGAACATCGCCAATAAGCCCACCTACTTTGACATCTAT ACGGCAGGAGCTGGTGTGGGTGACATTGGTGTGGAGGTGGAAGATCCCCAGGGGAAGAAC ACCGTGGAGTTGCTCGTGGAAGACAAAGGAAACCAGGTGTATCGATGTGTGTACAAACCC ATGCAGCCTGGCCCTCACGTGGTCAAGATCTTCTTTGCTGGGGACACTATTCCTAAGAGT CCCTTCGTTGTGCAGGTTGGGGAAGCCTGCAATCCAAATGCCTGCCGGGCCAGTGGCCGA GGCCTACAACCCAAAGGCGTCCGTATCCGGGAGACCACAGATTTCAAGGTTGACACCAAA GCTGCAGGAAGTGGGGAGCTCGGTGTAACCATGAAGGGTCCTAAGGGTCTGGAGGAGCTG GTGAAGCAGAAAGACTTTCTGGATGGGGTCTACGCATTCGAGTATTACCCCAGCACCCCG GGGAGATACAGCATTGCCATCACATGGGGGGGACACCACATTCCAAAGAGCCCCTTTGAA GTTCAAGTTGGCCCTGAAGCGGGTATGCAGAAAGTCCGTGCTTGGGGCCCTGGGCTCCAT GGTGGGATTGTCGGGCGGTCAGCGGACTTCGTGGTAGAATCCATTGGCTCTGAAGTGGGG TCTCTGGGGTTTGCCATTGAAGGCCCCTCTCAGGCAAAGATTGAGTACAACGACCAGAAT GATGGATCGTGTGATGTCAAATACTGGCCCAAGGAGCCTGGCGAATATGCTGTTCACATC ATGTGTGACGACGAAGACATCAAGGACAGCCCGTACATGGCCTTCATCCACCCAGCCACG GGAGGCTACAACCCTGATCTGGTTCGAGCATACGGGCCAGGTTTGGAGAAATCTGGATGC ATTGTCAACAACCTGGCCGAGTTCACTGTGGATCCTAAGGATGCTGGAAAAGCTCCCTTA AAGATATTTGCTCAGGATGGGGAAGGCCAACGCATTGACATCCAGATGAAGAACCGGATG GACGGCACATATGCATGCTCATACACCCCGGTGAAGGCCATCAAGCACACCATTGCTGTG GTCTGGGGAGGCGTGAACATCCCGCACAGCCCCTACAGGGTCAACATCGGGCAAGGTAGC CATCCTCAGAAGGTCAAAGTGTTTGGGCCAGGTGTGGAGAGAAGTGGTCTGAAGGCAAAT GAACCTACACACTTCACGGTGGACTGTACTGAGGCTGGGGAAGGTGATGTCAGTGTTGGC ATTAAGTGTGATGCCCGGGTGTTAAGTGAAGATGAGGAAGACGTGGATTTTGACATTATT CACAATGCCAATGATACGTTCACAGTCAAATATGTGCCTCCTGCTGCTGGGCGATACACT ATCAAAGTTCTCTTTGCATCTCAGGAAATCCCCGCCAGCCCTTTCAGAGTCAAAGTTGAC CCTTCCCACGATGCCAGCAAAGTGAAGGCAGAAGGCCCAGGGCTCAGCAAAGCAGGTGTG GAAAATGGGAAACCGACCCACTTCACTGTCTACACCAAGGGGGCTGGGAAAGCCCCGCTC AACGTGCAGTTCAACAGCCCTCTTCCTGGCGATGCAGTGAAGGATTTGGATATCATCGAT AATTATGACTACTCTCACACGGTTAAATATACACCCACCCAACAGGGCAACATGCAGGTT CTGGTGACTTACGGTGGCGATCCCATCCCTAAAAGCCCTTTCACTGTGGGTGTTGCTGCA CCGCTGGATCTGAGCAAGATAAAACTCAATGGGCTGGAAAACAGGGTGGAAGTTGGGAAG GATCAGGAGTTCACCGTTGATACCAGGGGGGCAGGAGGCCAGGGGAAGCTGGACGTGACA ATCCTCAGCCCCTCTCGGAAGGTCGTGCCATGCCTAGTGACACCTGTGACAGGCCGGGAG AACAGCACGGCCAAGTTCATCCCTCGGGAGGAGGGGCTGTATGCTGTAGACGTGACCTAC GATGGACACCCTGTGCCCGGGAGCCCCTACACAGTGGAGGCCTCGCTGCCACCAGATCCC AGCAAGGTGAAGGCCCACGGTCCCGGCCTCGAAGGTGGTCTCGTGGGCAAGCCTGCCGAG TTCACCATCGATACCAAAGGAGCTGGTACTGGAGGTCTGGGCTTAACGGTGGAAGGTCCG TGCGAGGCCAAAATCGAGTGCTCCGACAATGGTGATGGGACCTGCTCCGTCTCTTACCTT CCCACAAAACCCGGGGAGTACTTCGTCAACATCCTCTTTGAAGAAGTCCACATACCTGGG TCTCCCTTCAAAGCTGACATTGAAATGCCCTTTGACCCCTCTAAAGTCGTGGCATCGGGG CCAGGTCTCGAGCACGGGAAGGTGGGTGAAGCTGGCCTCCTTAGCGTCGACTGCTCGGAA GCGGGACCGGGGGCCCTGGGCCTGGAAGCTGTCTCGGACTCGGGAACAAAAGCCGAAGTC AGTATTCAGAACAACAAAGATGGCACCTACGCGGTGACCTACGTGCCCCTGACGGCCGGC ATGTACACGTTGACCATGAAGTATGGTGGCGAACTCGTGCCACACTTCCCCGCCCGGGTC AAGGTGGAGCCCGCCGTGGACACCAGCAGGATCAAAGTCTTTGGACCAGGAATAGAAGGG AAAGATGTGTTCCGGGAAGCTACCACCGACTTTACAGTTGACTCTCGGCCGCTGACCCAG GTTGGGGGTGACCACATCAAGGCCCACATTGCCAACCCCTCAGGGGCCTCCACCGAGTGC TTTGTCACAGACAATGCGGATGGGACCTACCAGGTGGAATACACACCCTTTGAGAAAGGT CTCCATGTAGTGGAGGTGACATATGATGACGTGCCTATCCCAAACAGTCCCTTCAAGGTG GCTGTCACTGAAGGCTGCCAGCCATCTAGGGTGCAAGCCCAAGGACCTGGATTGAAAGAG GCCTTTACCAACAAGCCCAATGTCTTCACCGTGGTTACCAGAGGCGCAGGAATTGGTGGG CTTGGCATAACTGTTGAGGGACCATCAGAGTCGAAGATAAATTGCAGAGACAACAAGGAT GGCAGCTGCAGTGCTGAGTACATTCCTTTCGCACCGGGGGATTACGATGTTAATATCACA TATGGAGGAGCCCACATCCCCGGCAGCCCCTTCAGGGTTCCTGTGAAGGATGTTGTGGAC CCCAGCAAGGTCAAGATTGCCGGCCCCGGGCTGGGCTCAGGCGTCCGAGCCCGTGTCCTG CAGTCCTTCACGGTGGACAGCAGCAAGGCTGGCCTGGCTCCGCTGGAAGTGAGGGTTCTG GGCCCACGAGGCTTGGTGGAGCCAGTGAACGTGGTGGACAATGGAGATGGCACACACACA GTAACCTACACCCCATCTCAGGAGGGACCTTACATGGTCTCAGTTAAATATGCTGATGAA GAGATTCCTCGCAGTCCCTTCAAGGTCAAGGTCCTTCCCACATATGATGCCAGCAAAGTG ACTGCCAGTGGCCCCGGCCTTAGTTCCTATGGTGTGCCTGCCAGTCTACCTGTGGACTTT GCAATTGATGCCCGAGATGCCGGGGAAGGCCTGCTTGCTGTTCAAATAACGGACCAAGAA GGAAAACCCAAAAGAGCCATTGTCCATGACAATAAAGATGGCACGTATGCTGTCACCTAC ATCCCCGACAAGACTGGGCGCTATATGATTGGAGTCACCTACGGGGGTGACGACATCCCA CTTTCTCCTTATCGCATCCGAGCCACACAGACGGGTGATGCCAGCAAGTGCCTGGCCACG GGTCCTGGAATCGCCTCCACTGTGAAAACTGGCGAAGAAGTAGGCTTTGTGGTTGATGCC AAGACTGCCGGGAAGGGTAAAGTGACCTGCACGGTTCTGACCCCAGATGGCACTGAGGCC GAGGCCGATGTCATTGAGAATGAAGATGGAACCTATGACATCTTCTACACAGCTGCCAAG CCGGGCACATATGTGATCTATGTGCGCTTCGGTGGTGTTGATATTCCTAACAGCCCCTTC ACTGTCATGGCCACAGATGGGGAAGTCACAGCCGTGGAGGAGGCACCGGTGACCGAAGAG GCCTATGTCCCAGTGAGTGACATGAACGGCCTGGGATTTAAGCCTTTTGACCTGGTCATT CCGTTTGCTGTCAGGAAAGGAGAAATCACTGGAGAGGTCCACATGCCTTCTGGGAAGACA GCCACACCTGAGATTGTGGACAACAAGGACGGCACGGTCACTGTTAGATATGCCCCCACT GAGGTCGGGCTCCATGAGATGCACATCAAATACATGGGCAGCCACATCCCTGAGAGCCCA CTCCAGTTCTACGTGAACTACCCCAACAGTGGAAGTGTTTCTGCATACGGTCCAGGCCTC GTGTATGGAGTGGCCAACAAAACTGCCACCTTCACCATCGTCACAGAGGATGCAGGAGAA GGTGGTCTGGACTTGGCTATTGAGGGCCCCTCAAAAGCAGAAATCAGCTGCATTGACAAT AAAGATGGGACATGCACAGTGACCTACCTGCCGACTCTGCCAGGCGACTACAGCATTCTG GTCAAGTACAATGACAAGCACATCCCTGGCAGCCCCTTCACAGCCAAGATCACAGATGAC AGCAGGCGGTGCTCCCAGGTGAAGTTGGGCTCAGCCGCTGACTTCCTGCTCGACATCAGT GAGACTGACCTCAGCAGCCTGACGGCCAGCATTAAGGCCCCATCTGGCCGAGACGAGCCC TGTCTCCTGAAGAGGCTGCCCAACAACCACATTGGCATCTCCTTCATCCCCCGGGAAGTG GGCGAACATCTGGTCAGCATCAAGAAAAATGGCAACCATGTGGCCAACAGCCCCGTGTCT ATCATGGTGGTCCAGTCGGAGATTGGTGACGCCCGCCGAGCCAAAGTCTATGGCCGCGGC CTGTCAGAAGGCCGGACTTTCGAGATGTCTGACTTCATCGTGGACACAAGGGATGCAGGT TATGGTGGCATATCCTTGGCGGTGGAAGGCCCCAGCAAAGTGGACATCCAGACGGAGGAC CTGGAAGATGGCACCTGCAAAGTCTCCTACTTCCCTACCGTGCCTGGGGTTTATATCGTC TCCACCAAATTCGCTGACGAGCACGTGCCTGGGAGCCCATTTACCGTGAAGATCAGTGGG GAGGGAAGAGTCAAAGAGAGCATCACCCGCACCAGTCGGGCCCCGTCCGTGGCCACTGTC GGGAGCATTTGTGACCTGAACCTGAAAATCCCAGAAATCAACAGCAGTGATATGTCGGCC CACGTCACCAGCCCCTCTGGCCGTGTGACTGAGGCAGAGATTGTGCCCATGGGGAAGAAC TCACACTGCGTCCGGTTTGTGCCCCAGGAGATGGGCGTGCACACGGTCAGCGTCAAGTAC CGTGGGCAGCACGTCACCGGCAGCCCCTTCCAGTTCACCGTGGGGCCACTTGGTGAAGGA GGCGCCCACAAGGTGCGGGCAGGAGGCCCTGGCCTGGAGAGAGGAGAAGCGGGAGTCCCA GCTGAGTTCAGCATTTGGACCCGGGAAGCAGGCGCTGGAGGCCTCTCCATCGCTGTTGAG GGCCCCAGTAAGGCCGAGATTACATTCGATGACCATAAAAATGGGTCGTGCGGTGTATCT TATATTGCCCAAGAGCCTGGTAACTACGAGGTGTCCATCAAGTTCAATGATGAGCACATC CCGGAAAGCCCCTACCTGGTGCCGGTCATCGCACCCTCCGACGACGCCCGCCGCCTCACT GTTATGAGCCTTCAGGAATCGGGATTAAAAGTTAACCAGCCAGCATCCTTTGCTATAAGG TTGAATGGCGCAAAAGGCAAGATTGATGCAAAGGTGCACAGCCCCTCTGGAGCCGTGGAG GAGTGCCACGTGTCTGAGCTGGAGCCAGATAAGTATGCTGTTCGCTTCATCCCTCATGAG AATGGTGTCCACACCATCGATGTCAAGTTCAATGGGAGCCACGTGGTTGGAAGCCCCTTC AAAGTGCGCGTTGGGGAGCCTGGACAAGCGGGGAACCCTGCCCTGGTGTCCGCCTATGGC ACGGGACTCGAAGGGGGCACCACAGGTATCCAGTCGGAATTCTTTATTAACACCACCCGA GCAGGTCCAGGGACATTATCCGTCACCATCGAAGGCCCATCCAAGGTTAAAATGGATTGC CAGGAAACACCTGAAGGGTACAAAGTCATGTACACCCCCATGGCTCCTGGTAACTACCTG ATCAGCGTCAAATACGGTGGGCCCAACCACATCGTGGGCAGTCCCTTCAAGGCCAAGGTG ACAGGCCAGCGTCTAGTTAGCCCTGGCTCAGCCAACGAGACCTCATCCATCCTGGTGGAG TCAGTGACCAGGTCGTCTACAGAGACCTGCTATAGCGCCATTCCCAAGGCATCCTCGGAC GCCAGCAAGGTGACCTCTAAGGGGGCAGGGCTCTCAAAGGCCTTTGTGGGCCAGAAGAGT TCCTTCCTGGTGGACTGCAGCAAAGCTGGCTCCAACATGCTGCTGATCGGGGTCCATGGG CCCACCACCCCCTGCGAGGAGGTCTCCATGAAGCATGTAGGCAACCAGCAATACAACGTC ACATACGTCGTCAAGGAGAGGGGCGATTATGTGCTGGCTGTGAAGTGGGGGGAGGAACAC ATCCCTGGCAGCCCTTTTCATGTCACAGTGCCT |
Restriction Sites | Please inquire |
ACCN | NM_001164318 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001164318.1, NP_001157790.1 |
RefSeq Size | 9434 bp |
RefSeq ORF | 7776 bp |
Locus ID | 2317 |
Cytogenetics | 3p14.3 |
Protein Pathways | Focal adhesion, MAPK signaling pathway |
Gene Summary | 'This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009]' Transcript Variant: This variant (3) lacks an alternate in-frame exon and uses an alternate splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 3) is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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