SETDB2 (NM_001160308) Human Untagged Clone

CAT#: SC327637

SETDB2 (untagged)-Human SET domain bifurcated 2 (SETDB2) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SETDB2
• Synonyms: C13orf4; CLLD8; CLLL8; KMT1F
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001160308, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGAGAAAAAAATGGCGATGCAAAAACTTTCTGGATGGAGCTAGAAGATGATGGAAAAGTGGACTTCA
  TTTTTGAACAAGTACAAAATGTGCTGCAGTCACTGAAACAAAAGATCAAAGATGGGTCTGCCACCAATAA
  AGAATACATCCAAGCAATGATTCTAGTGAATGAAGCAACTATAATTAACAGTTCAACATCAATAAAGGAT
  CCTATGCCTGTGACTCAGAAGGAACAGGAAAACAAATCCAATGCATTTCCCTCTACATCATGTGAAAACT
  CCTTTCCAGAAGACTGTACATTTCTAACAACAGAAAATAAGGAAATTCTCTCTCTTGAAGATAAAGTTGT
  AGACTTTAGAGAAAAAGACTCATCTTCGAATTTATCTTACCAAAGTCATGACTGCTCTGGTGCTTGTCTG
  ATGAAAATGCCACTGAACTTGAAGGGAGAAAACCCTCTGCAGCTGCCAATCAAATGTCACTTCCAAAGAC
  GACATGCAAAGACAAACTCTCATTCTTCAGCACTCCACGTGAGTTATAAAACCCCTTGTGGAAGGAGTCT
  ACGAAACGTGGAGGAAGTTTTTCGTTACCTGCTTGAGACAGAGTGTAACTTTTTATTTACAGATAACTTT
  TCTTTCAATACCTATGTTCAGTTGGCTCGGAATTACCCAAAGCAAAAAGAAGTTGTTTCTGATGTGGATA
  TTAGCAATGGAGTGGAATCAGTGCCCATTTCTTTCTGTAATGAAATTGACAGTAGAAAGCTCCCACAGTT
  TAAGTACAGAAAGACTGTGTGGCCTCGAGCATATAATCTAACCAACTTTTCCAGCATGTTTACTGATTCC
  TGTGACTGCTCTGAGGGCTGCATAGACATAACAAAATGTGCATGTCTTCAACTGACAGCAAGGAATGCCA
  AAACTTCCCCCTTGTCAAGTGACAAAATAACCACTGGATATAAATATAAAAGACTACAGAGACAGATTCC
  TACTGGCATTTATGAATGCAGCCTTTTGTGCAAATGTAATCGACAATTGTGTCAAAACCGAGTTGTCCAA
  CATGGTCCTCAAGTGAGGTTACAGGTGTTCAAAACTGAGCAGAAGGGATGGGGTGTACGCTGTCTAGATG
  ACATTGACAGAGGGACATTTGTTTGCATTTATTCAGGAAGATTACTAAGCAGAGCTAACACTGAAAAATC
  TTATGGTATTGATGAAAACGGGAGAGATGAGAATACTATGAAAAATATATTTTCAAAAAAGAGGAAATTA
  GAAGTTGCATGTTCAGATTGTGAAGTTGAAGTTCTCCCATTAGGATTGGAAACACATCCTAGAACTGCTA
  AAACTGAGAAATGTCCACCAAAGTTCAGTAATAATCCCAAGGAGCTTACTGTGGAAACGAAATATGATAA
  TATTTCAAGAATTCAATATCATTCAGTTATTAGAGATCCTGAATCCAAGACAGCCATTTTTCAACACAAT
  GGGAAAAAAATGGAATTTGTTTCCTCGGAGTCTGTCACTCCAGAAGATAATGATGGATTTAAACCACCCC
  GAGAGCATCTGAACTCTAAAACCAAGGGAGCACAAAAGGACTCAAGTTCAAACCATGTTGATGAGTTTGA
  AGATAATCTGCTGATTGAATCAGATGTGATAGATATAACTAAATATAGAGAAGAAACTCCACCAAGGAGC
  AGATGTAACCAGGCGACCACATTGGATAATCAGAATATTAAAAAGGCAATTGAGGTTCAAATTCAGAAAC
  CCCAAGAGGGACGATCTACAGCATGTCAAAGACAGCAGGTATTTTGTGATGAAGAGTTGCTAAGTGAAAC
  CAAGAATACTTCATCTGATTCTCTAACAAAGTTCAATAAAGGGAATGTGTTTTTATTGGATGCCACAAAA
  GAAGGAAATGTCGGCCGCTTCCTTAATCATAGTTGTTGCCCAAATCTCTTGGTACAGAATGTTTTTGTAG
  AAACACACAACAGGAATTTTCCATTGGTGGCATTCTTCACCAACAGGTATGTGAAAGCAAGAACAGAGCT
  AACATGGGATTATGGCTATGAAGCTGGGACTGTGCCTGAGAAGGAAATCTTCTGCCAATGTGGGGTTAAT
  AAATGTAGAAAAAAAATATTATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001160308
• ORF Size: 2124 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001160308.2, NP_001153780.1
• RefSeq Size: 6200
• RefSeq ORF: 2124
• Locus ID: 83852
• Protein Families: Druggable Genome
• Protein Pathways: Lysine degradation
• Gene Summary: This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The encoded isoform (b) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.