PPP1R16B (NM_001172735) Human Untagged Clone

CAT#: SC328867

PPP1R16B (untagged)-Human protein phosphatase 1 regulatory (inhibitor) subunit 16B (PPP1R16B) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPP1R16B
• Synonyms: ANKRD4; TIMAP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001172735, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCAGTCACGTGGACCTGCTGACGGAGCTGCAGCTGCTGGAGAAGGTGCCCACGCTGGAGCGGCTGC
  GGGCTGCCCAGAAGCGCCGGGCCCAGCAGCTGAAGAAATGGGCACAGTACGAGCAGGACTTGCAGCACCG
  CAAGCGAAAGCATGAGCGGAAGCGCAGCACGGGCGGCCGCCGCAAGAAAGTGTCCTTCGAGGCCAGCGTG
  GCCCTGCTGGAGGCCTCGCTGAGGAACGACGCCGAGGAAGTACGCTACTTCCTGAAGAATAAGGTCAGCC
  CTGATTTGTGCAATGAGGACGGACTCACAGCCCTACACCAGTGCTGCATCGACAACTTTGAGGAAATTGT
  GAAGCTGCTCCTCTCCCATGGTGCCAATGTGAACGCCAAGGACAACGAGCTGTGGACACCTCTCCATGCT
  GCAGCCACCTGCGGCCACATCAACCTGGTGAAGATCCTCGTTCAGTATGGGGCCGACTTGCTTGCTGTCA
  ACTCGGATGGGAACATGCCATATGACCTCTGCGAGGATGAACCCACCCTGGATGTCATCGAGACCTGCAT
  GGCATACCAGGGCATCACCCAAGAGAAAATCAACGAGATGCGGGTGGCTCCTGAGCAGCAGATGATTGCG
  GACATCCACTGCATGATCGCAGCGGGCCAGGACCTGGACTGGATAGATGCCCAGGGTGCCACACTGATGC
  AGATGGCAGAGCTATTGGTGTCCCATGGAGCTAGTCTCAGTGCAAGGACATCCATGGATGAGATGCCAAT
  AGACCTGTGCGAGGAGGAAGAGTTCAAGGTCCTGCTGCTGGAGCTAAAACACAAGCATGATGTGATCATG
  AAGTCACAGCTGAGGCACAAGTCATCCTTGAGCCGGAGGACCTCCAGCGCAGGCAGCCGTGGGAAGGTGG
  TGCGGCGAGCCAGCCTGTCGGACAGGACCAACCTGTATAGGAAGGAGTATGAGGGAGAGGCCATCCTGTG
  GCAGCGGAGTGCAGCTGAGGATCAGCGGACCTCCACCTACAACGGGGACATCAGGGAGACCAGGACAGAC
  CAAGAGAATAAGGACCCTAACCCCAGGCTGGAGAAGCCCGTGCTACTCTCCGAATTTCCTACCAAGATCC
  CACGAGGTGAACTGGACATGCCTGTTGAGAATGGCCTCCGGGCTCCGGTCAGTGCCTACCAGTATGCGCT
  GGCCAACGGGGATGTCTGGAAGGTGCATGAGGTGCCTGACTACAGCATGGCCTATGGCAACCCTGGCGTG
  GCCGACGCCACCCCGCCCTGGAGCAGCTACAAGGAACAGAGCCCTCAGACGCTTCTGGAGCTGAAGCGGC
  AGCGGGCTGCAGCCAAGCTGCTCAGCCACCCCTTCCTTAGCACACACCTGGGCAGCAGCATGGCCAGGAC
  GGGCGAGAGTAGCAGTGAAGGCAAGGCCCCCTTGATCGGAGGCAGAACTTCACCGTACAGCAGCAATGGG
  ACCTCGGTATATTACACGGTCACCAGCGGAGATCCCCCACTCTTAAAGTTCAAGGCCCCCATAGAGGAGA
  TGGAGGAGAAGGTGCATGGCTGTTGCCGTATCTCCTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001172735
• ORF Size: 1578 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001172735.2, NP_001166206.1
• RefSeq Size: 6157
• RefSeq ORF: 1578
• Locus ID: 26051
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
  Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, as compared to variant 1. The resulting isoform (2) lacks an internal segment, as compared to isoform 1. This isoform (2) may undergo similar processing as isoform 1.