Cortactin (CTTN) (NM_001184740) Human Untagged Clone

CAT#: SC329013

CTTN (untagged)-Human cortactin (CTTN) transcript variant 3


  "NM_001184740" in other vectors (2)

Reconstitution Protocol

USD 760.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CTTN
Synonyms EMS1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_001184740, the custom clone sequence may differ by one or more nucleotides
ATGTGGAAAGCTTCAGCAGGCCACGCTGTGTCCATCGCCCAGGATGACGCGGGGGCCGAT
GACTGGGAGACCGACCCTGATTTTGTGAATGATGTGAGTGAGAAGGAGCAAAGATGGGGT
GCCAAGACGGTGCAGGGCTCCGGGCACCAGGAGCATATCAACATACACAAGCTGAGGGAG
AATGTCTTTCAAGAGCATCAGACCCTTAAGGAGAAGGAACTTGAAACAGGACCAAAAGCT
TCCCATGGCTATGGAGGGAAATTTGGTGTGGAACAAGACCGAATGGATAAGTCAGCTGTC
GGCCACGAATATCAGTCGAAACTTTCCAAGCACTGCTCGCAGGTGGACTCGGTCCGTGGC
TTCGGAGGCAAGTTTGGTGTCCAGATGGACAGAGTTGATCAGTCTGCTGTAGGCTTTGAA
TACCAGGGGAAGACTGAGAAGCATGCCTCCCAGAAAGACTACTCCAGTGGTTTTGGCGGC
AAGTATGGCGTGCAGGCCGACCGAGTAGACAAGAGCGCGGTGGGCTTCGACTACCAGGGC
AAGACGGAGAAGCACGAGTCACAGAGAGATTACTCCAAAGGTTTCGGCGGCAAATACGGT
ATCGACAAGGACAAAGTGGATAAGAGCGCCGTTGGCTTTGAGTATCAAGGCAAAACGGAG
AAGCACGAGTCCCAGAAAGACTATGTGAAAGGGTTTGGAGGAAAATTTGGTGTGCAGACA
GACAGACAAGACAAATGTGCCCTTGGCTGGGATCACCAGGAGAAATTGCAGCTGCATGAA
TCCCAAAAAGACTACTCCAAAGGATTCGGCGGGAAGTATGGGGTGCAGAAGGATCGGATG
GATAAGAATGCGTCAACCTTTGAGGATGTCACCCAGGTGTCCTCTGCCTACCAGAAGACA
GTACCTGTCGAAGCTGTGACCAGCAAAACAAGTAACATCAGAGCTAACTTTGAAAACCTC
GCTAAGGAGAAAGAGCAGGAGGACAGGCGGAAGGCGGAGGCGGAGAGAGCCCAGCGGATG
GCCAAGGAGCGGCAGGAGCAGGAAGAGGCCAGGAGGAAGCTGGAGGAGCAAGCCAGAGCC
AAAACGCAAACGCCCCCTGTGTCGCCCGCACCTCAGCCAACCGAGGAGAGGCTGCCCTCG
AGCCCCGTCTATGAGGATGCGGCTTCCTTCAAGGCAGAGCTGAGCTACAGAGGCCCTGTG
AGTGGGACGGAGCCGGAGCCCGTGTACAGCATGGAGGCCGCTGACTACCGAGAGGCCAGC
AGCCAGCAGGGCCTGGCCTATGCCACAGAGGCTGTCTATGAAAGCGCAGAGGCCCCGGGC
CACTATCCCGCAGAGGACAGCACCTACGATGAGTACGAGAACGATCTGGGGATCACAGCC
GTCGCCCTGTACGACTACCAGGCTGCGGGCGATGATGAGATCTCATTTGACCCTGATGAC
ATCATCACCAACATCGAGATGATTGACGACGGCTGGTGGCGCGGGGTGTGCAAGGGCCGC
TTCAGGGAGCTCGCATTCTCTTGTGTTCGTGTTGCCCTCGTGCCCATCAAGTGCAGTCGG
GACCTCCCAGGACAAGCACGAGGCCTCAGGTCGGCCCTGTGGCGGGTAGGCAGGAAGGAC
TGTCCCAGACGAGGGGCTTCCTCTAGAGTCTCACTGCTGGGGAGGAGAGGACTGGGCCTG
ATGGAAGTTAACCCGGAGCTAAGTCACCCAGAGCACAGGAGCTGCCATGTCAGATGGGAA
ATCTGCCTATGTCATACCGTGACAGCCCGCAGGATCAGGAAACTCATCTCCTTCCTGAGG
AGCCGGGAGGCTGGACCAGTCCCGTCGTGCAGTCAGGTGGGCGGTGTGTCTTTCCAGAAG
GTCACGTGGAAATGTCTCGGGACTTGGGTCCCGGAGTGCCCGTGA
Restriction Sites Please inquire     
ACCN NM_001184740
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001184740.1, NP_001171669.1
RefSeq Size 2325 bp
RefSeq ORF 1905 bp
Locus ID 2017
Cytogenetics 11q13.3
Protein Families Druggable Genome
Protein Pathways Pathogenic Escherichia coli infection, Tight junction
Gene Summary 'This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]'
Transcript Variant: This variant (3) uses different splice sites in the 3' coding region, which changes reading frame and the termination stop codon, compared to variant 1. The resulting protein (isoform c) has a longer and distinct C-terminus when it is compared to isoform a.

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