CHD8 (NM_001170629) Human Untagged Clone

CAT#: SC329391

CHD8 (untagged)-Human chromodomain helicase DNA binding protein 8 (CHD8) transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CHD8
• Synonyms: AUTS18; HELSNF1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001170629, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCAGACCCCATCATGGATCTGTTCGATGACCCAAATTTATTTGGCCTGGACTCTCTGACTGATGACA
  GCTTTAACCAGGTCACACAAGACCCCATTGAGGAAGCCCTTGGACTGCCAAGCTCTCTGGACTCCTTGGA
  TCAGATGAACCAGGATGGTGGAGGTGGTGATGTGGGGAATTCATCAGCAAGTGAACTGGTCCCTCCACCA
  GAGGAAACAGCTCCCACAGAACTTTCCAAAGAATCCACAGCTCCAGCTCCAGAATCCATAACCTTGCATG
  ATTATACCACTCAGCCTGCCAGCCAGGAGCAGCCAGCCCAACCTGTCTTACAGACATCGACGCCAACATC
  AGGACTTTTGCAAGTCTCCAAGAGCCAGGAGATCCTGAGCCAAGGGAATCCTTTCATGGGTGTCTCTGCC
  ACAGCTGTCTCCTCCAGTAGTGCTGGAGGGCAGCCACCTCAGTCAGCCCCTAAGATTGTTATCCTTAAGG
  CCCCACCAAGCTCCTCAGTCACTGGTGCCCATGTGGCACAAATTCAGGCCCAAGGTATCACCAGCACAGC
  TCAGCCCCTGGTGGCAGGCACAGCCAATGGTGGAAAAGTCACTTTTACCAAAGTGCTAACCGGCACACCC
  CTTCGACCAGGTGTTTCCATTGTCTCTGGTAATACAGTGTTGGCCGCCAAGGTCCCTGGGAACCAGGCTG
  CTGTTCAGCGCATTGTCCAGCCCAGCCGACCAGTAAAGCAGCTGGTCCTCCAGCCAGTTAAGGGTTCAGC
  TCCTGCTGGAAACCCTGGGGCCACAGGGCCCCCACTGAAGCCTGCAGTTACACTGACCTCTACACCTACC
  CAGGGTGAATCGAAACGCATCACCCTGGTCCTCCAGCAGCCACAGTCTGGAGGTCCCCAAGGACATCGGC
  ATGTTGTGCTAGGGAGTCTACCAGGCAAGATAGTGTTACAGGGCAACCAGCTGGCAGCCCTGACTCAAGC
  CAAGAATGCCCAAGGGCAGCCTGCCAAGGTAGTAACTATCCAGCTGCAGGTGCAGCAGCCACAGCAAAAA
  ATCCAGATTGTACCACAACCACCATCATCGCAGCCACAGCCCCAGCAGCCACCCTCCACCCAGCCAGTGA
  CTCTGTCCTCTGTACAGCAGGCTCAGATAATGGGACCAGGACAAAGCCCAGGACAAAGACTTTCAGTACC
  AGTCAAGGTGGTACTGCAGCCACAGGCTGGCTCTTCCCAAGGGGCCTCTTCTGGGCTCTCTGTAGTTAAA
  GTTCTGAGTGCCAGTGAAGTGGCAGCTTTGTCATCACCAGCAAGCTCTGCTCCTCATTCGGGGGGAAAGA
  CAGGAATGGAGGAAAACCGCAGATTGGAACACCAGAAGAAGCAAGAGAAAGCAAATCGGATTGTAGCAGA
  GGCCATTGCGAGAGCCCGTGCCCGCGGTGAGCAGAACATACCTCGAGTCTTAAATGAGGACGAGTTGCCC
  AGCGTTCGGCCAGAGGAGGAAGGCGAGAAGAAACGCAGGAAGAAGAGTGCTGGGGAGAGGCTGAAAGAGG
  AGAAGCCAAAGAAGAGTAAAACATCTGGTGCCTCCAAAACAAAGGGCAAGAGCAAGCTCAACACCATCAC
  TCCTGTAGTGGGTAAGAAGAGAAAACGTAATACCTCATCTGATAATTCAGATGTGGAAGTCATGCCTGCA
  CAGTCACCTCGAGAAGATGAAGAAAGCAGCATTCAGAAGAGACGCTCAAACCGCCAAGTTAAGCGAAAAA
  AATATACAGAGGACCTGGATATAAAGATCACAGATGATGAAGAAGAAGAAGAGGTGGATGTAACTGGTCC
  AATAAAACCTGAGCCTATCCTCCCTGAACCAGTGCAAGAACCAGATGGCGAGACTTTGCCTTCCATGCAG
  TTCTTTGTGGAGAATCCCAGTGAAGAAGATGCAGCCATTGTAGACAAAGTGCTTTCTATGCGGATTGTGA
  AGAAGGAGCTCCCTTCTGGACAATATACTGAAGCAGAAGAATTCTTTGTCAAGTACAAGAACTACTCCTA
  TCTGCATTGTGAATGGGCTACTATCTCCCAACTAGAGAAGGATAAGAGGATACATCAAAAATTAAAGCGC
  TTCAAAACCAAAATGGCTCAGATGAGACACTTCTTCCATGAGGATGAAGAGCCCTTTAATCCAGACTACG
  TAGAGGTGGATAGGATATTGGATGAGTCTCACAGTATTGACAAGGACAATGGGGAGCCCGTTATTTACTA
  CCTGGTGAAATGGTGCTCTCTGCCCTATGAGGATAGCACATGGGAGCTAAAAGAAGATGTTGATGAGGGC
  AAGATTCGAGAATTTAAACGGATTCAGTCAAGGCACCCAGAACTCAAAAGGGTGAATCGTCCGCAGGCAA
  GTGCCTGGAAGAAATTGGAGCTATCACATGAATATAAAAACAGAAACCAGCTACGGGAATATCAGTTGGA
  AGGGGTTAATTGGCTGCTCTTTAATTGGTATAACAGGCAGAACTGCATCCTGGCTGATGAGATGGGATTG
  GGCAAAACTATTCAGTCCATTGCCTTCTTGCAGGAAGTATATAATGTGGGCATCCATGGTCCCTTCTTGG
  TCATTGCCCCACTGTCCACAATTACTAACTGGGAGCGAGAATTTAATACATGGACAGAAATGAACACTAT
  TGTGTACCATGGCAGTCTGGCCAGCAGGCAGATGATTCAACAGTATGAAATGTACTGCAAAGATTCACGG
  GGACGCCTCATCCCAGGCGCATACAAGTTTGACGCTCTGATCACCACTTTTGAGATGATTTTGTCAGATT
  GTCCTGAGCTTCGTGAAATTGAATGGCGTTGTGTTATCATTGATGAAGCCCATCGACTGAAAAACCGTAA
  TTGCAAGCTGCTTGATAGTCTCAAGCACATGGACCTGGAACACAAGGTGCTACTCACAGGAACACCATTG
  CAAAATACTGTAGAAGAACTGTTTAGCTTGCTTCATTTCTTGGAACCGTCACAATTTCCCTCAGAATCAG
  AGTTTCTCAAGGACTTTGGGGATCTCAAGACAGAGGAACAGGTTCAAAAGCTACAGGCCATTCTTAAGCC
  AATGATGCTGAGAAGACTCAAAGAGGATGTTGAAAAAAACTTGGCACCCAAACAGGAAACAATTATTGAA
  GTAGAGCTGACTAATATCCAGAAGAAATACTATCGGGCTATTTTGGAGAAGAATTTCTCCTTCCTTTCCA
  AAGGGGCAGGTCATACCAACATGCCTAATCTACTTAACACAATGATGGAGTTGCGCAAGTGCTGCAACCA
  CCCATATCTCATCAATGGTGCTGAAGAAAAAATCCTAACAGAATTCCGTGAAGCTTGCCATATTATACCT
  CATGACTTTCACCTGCAGGCCATGGTTCGTTCAGCCGGCAAACTGGTTCTTATTGACAAGTTGCTTCCAA
  AGCTTAAAGCTGGTGGCCATAAAGTTCTGATCTTCTCTCAGATGGTGCGCTGCCTAGACATCCTAGAGGA
  TTATTTAATCCAGAGGAGGTACTTATATGAACGTATTGATGGGCGAGTTAGAGGCAACCTTCGACAGGCT
  GCCATTGACCGCTTCAGCAAGCCTGACTCAGACCGCTTTGTCTTCTTACTGTGTACCCGGGCTGGTGGAC
  TTGGTATTAATCTTACAGCTGCTGATACCTGCATCATCTTTGATTCAGACTGGAATCCACAAAATGACCT
  GCAGGCCCAGGCACGATGTCATCGAATTGGGCAGAGCAAAGCTGTGAAGGTGTACCGCCTCATCACTCGT
  AATTCCTACGAGAGAGAGATGTTTGATAAGGCCAGCCTCAAGTTGGGGTTGGATAAGGCTGTGCTTCAAT
  CCATGAGTGGTCGGGATGGCAACATTACTGGAATCCAACAGTTCTCTAAGAAGGAGATTGAAGATCTTTT
  AAGAAAAGGAGCATATGCAGCCATCATGGAGGAAGATGATGAAGGCTCCAAGTTTTGTGAAGAGGACATT
  GACCAGATCTTGTTAAGACGAACTACAACCATCACCATTGAATCTGAAGGAAAAGGTTCCACCTTTGCTA
  AGGCAAGCTTTGTTGCTTCTGAAAACAGGACAGATATTTCTTTGGATGACCCCAACTTTTGGCAAAAGTG
  GGCCAAAAAGGCTGACCTAGACATGGATCTGCTCAACAGCAAGAATAATTTGGTAATTGACACACCTAGA
  GTACGAAAACAAACGCGCCACTTTAGCACTCTGAAAGATGATGACCTGGTGGAATTCTCTGATTTGGAAA
  GTGAGGATGATGAGCGGCCACGCTCCCGCAGACATGACCGTCATCATGCCTATGGGCGCACTGACTGCTT
  TCGGGTGGAAAAGCATCTCCTGGTATATGGTTGGGGACGATGGCGAGATATTTTATCTCATGGACGCTTC
  AAGCGACGTATGACTGAACGAGATGTGGAGACCATTTGTCGGGCCATTCTCGTGTACTGTCTTCTACACT
  ACCGTGGGGATGAAAATATTAAAGGCTTCATCTGGGACTTGATTAGCCCAGCTGAAAATGGCAAGACAAA
  AGAATTGCAGAATCATTCAGGTCTATCTATCCCTGTGCCTCGTGGACGCAAAGGAAAAAAAGTAAAGTCA
  CAAAGCACTTTTGATATCCATAAGGCAGATTGGATCCGGAAATATAACCCTGACACTTTGTTCCAAGATG
  AAAGTTATAAGAAGCACTTGAAACATCAGTGTAACAAGGTACTGTTGCGGGTACGAATGCTATACTACCT
  GAGGCAGGAGGTTATTGGAGACCAAGCAGAAAAGGTGTTAGGGGGTGCGATTGCCAGTGAGATTGACATA
  TGGTTCCCAGTAGTGGATCAACTGGAGGTTCCAACAACTTGGTGGGACAGTGAGGCTGACAAGTCGCTGC
  TCATTGGAGTCTTTAAACATGGCTATGAGAAATATAATACCATGAGGGCAGACCCAGCCTTATGTTTCCT
  AGAAAAGGCTGGCCGACCAGATGACAAAGCAATTGCAGCAGAACATCGAGTGTTGGATAACTTCTCTGAC
  ATAGTAGAAGGGGTTGACTTTGATAAAGATTGTGAAGATCCTGAATATAAACCACTCCAAGGTCCCCCAA
  AGGACCAAGATGATGAGGGTGATCCCTTGATGATGATGGATGAGGAGATCTCAGTGATTGATGGAGATGA
  AGCCCAGGTGACCCAACAGCCAGGCCATTTATTCTGGCCTCCGGGCTCTGCCCTAACAGCTAGGCTTCGG
  CGTCTAGTAACAGCGTATCAGCGCAGCTACAAGAGAGAACAAATGAAGATAGAGGCTGCAGAACGTGGGG
  ACCGGCGAAGGCGGCGTTGTGAAGCAGCCTTCAAGCTGAAAGAAATTGCACGGCGGGAGAAACAACAACG
  ATGGACAAGGCGTGAACAAACTGATTTTTATCGAGTGGTGTCTACGTTTGGTGTGGAATATGACCCTGAC
  ACCATGCAGTTCCATTGGGATCGCTTCCGCACTTTTGCTCGACTAGACAAAAAGACAGATGAAAGCCTTA
  CCAAGTACTTCCATGGCTTTGTGGCCATGTGCCGCCAAGTATGCCGCCTTCCCCCAGCAGCTGGAGATGA
  ACCCCCCGACCCTAACCTGTTCATTGAGCCCATCACTGAGGAGAGAGCCTCACGGACTCTCTACCGTATA
  GAATTGCTTCGGCGCTTACGGGAACAAGTTTTATGCCACCCCCTTTTGGAAGATCGGCTGGCATTGTGTC
  AGCCTCCTGGTCCTGAATTGCCCAAATGGTGGGAGCCTGTTCGGCATGATGGGGAGCTTCTAAGAGGGGC
  AGCCCGCCATGGGGTGAGCCAAACAGACTGCAACATCATGCAGGACCCAGACTTCTCTTTTCTGGCTGCC
  CGTATGAATTATATGCAGAACCATCAAGCAGGAGCACCAGCTCCATCCTTGTCACGCTGCTCTACTCCAC
  TGCTGCACCAGCAGTATACCTCACGCACTGCCTCACCACTGCCCCTGCGCCCAGATGCTCCTGTTGAAAA
  GTCACCCGAGGAGACAGCTACCCAGGTCCCCAGTCTGGAGAGTCTGACTTTAAAGCTAGAGCACGAGGTG
  GTGGCCAGGAGCCGACCAACCCCACAAGACTATGAGATGCGAGTATCCCCCTCTGATACTACCCCTCTGG
  TTTCCCGGAGTGTTCCACCAGTCAAACTGGAGGATGAGGATGATTCGGACTCTGAGCTGGACTTGAGCAA
  GCTGTCACCATCTTCTTCTTCTTCCTCATCCTCATCCAGCTCCAGCTCCAGCACTGATGAGAGTGAGGAT
  GAGAAGGAAGAGAAGCTAACTGACCAGTCCCGCTCAAAGCTCTATGATGAAGAGAGTCTCCTGTCCCTCA
  CTATGTCCCAAGATGGATTCCCAAATGAAGATGGAGAACAAATGACCCCTGAGCTTCTGCTACTGCAGGA
  AAGACAAAGAGCCTCTGAGTGGCCCAAGGATCGTGTCCTGATAAACCGTATTGACCTCGTCTGCCAGGCT
  GTACTCTCAGGGAAGTGGCCTTCTAGCCGTAGGAGCCAGGAAATGGTAACAGGAGGAATTTTGGGGCCAG
  GCAACCACTTGCTAGACAGTCCCTCATTGACTCCTGGAGAATATGGTGACTCTCCAGTCCCCACACCACG
  AAGTAGTAGTGCAGCTTCCATGGCAGAGGAGGAAGCATCTGCAGTCAGCACAGCGGCAGCCCAGTTCACC
  AAACTTCGCCGAGGCATGGATGAAAAGGAGTTTACAGTTCAAATCAAAGATGAGGAAGGATTGAAGTTAA
  CATTCCAGAAGCACAAGTTGATGGCGAATGGAGTAATGGGAGATGGACATCCACTGTTTCATAAGAAGAA
  GGGGAACAGAAAGAAGCTAGTAGAGCTGGAGGTGGAGTGCATGGAAGAGCCTAATCACCTTGATGTGGAC
  CTGGAGACCCGGATCCCTGTCATCAATAAGGTGGATGGTACTTTGCTGGTGGGTGAGGATGCCCCTCGCC
  GGGCTGAACTGGAGATGTGGTTACAGGGTCATCCAGAGTTTGCTGTTGATCCCCGATTTCTAGCGTATAT
  GGAGGATCGCAGAAAACAGAAGTGGCAAAGATGTAAAAAAAATAATAAGGCAGAATTGAACTGTTTGGGA
  ATGGAACCAGTACAGACAGCTAACTCTAGAAATGGGAAAAAGGGTCATCACACTGAAACGGTGTTCAACC
  GGGTTTTGCCAGGGCCTATTGCACCAGAGAGCAGCAAGAAGCGGGCCCGTAGGATGCGACCAGACCTTTC
  TAAGATGATGGCCCTCATGCAGGGTGGAAGCACTGGGTCTCTATCTCTGCATAACACGTTCCAACACAGC
  AGTAGTGGCCTACAGTCTGTGTCATCTTTGGGTCACAGCAGTGCCACTTCTGCATCTTTGCCTTTTATGC
  CATTTGTGATGGGTGGTGCACCATCATCCCCTCATGTAGACTCCAGCACCATGCTTCATCACCACCACCA
  CCACCCCCACCCCCACCATCACCACCATCACCATCCAGGCTTGAGAGCCCCTGGCTACCCCTCTTCACCA
  GTGACTACCGCCTCTGGTACTACCTTGCGGTTGCCACCACTGCAACCTGAGGAGGATGACGATGAGGATG
  AAGAAGATGATGATGACTTATCTCAGGGCTATGATAGCTCAGAAAGGGACTTCTCACTCATTGATGATCC
  TATGATGCCAGCTAACTCAGACTCCAGTGAAGATGCTGATGACTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001170629
• ORF Size: 7746 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001170629.1, NP_001164100.1
• RefSeq Size: 8254
• RefSeq ORF: 7746
• Locus ID: 57680
• Protein Pathways: Wnt signaling pathway
• Gene Summary: This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript and protein alignments.