PDE1C (NM_001191059) Human Untagged Clone

CAT#: SC329425

PDE1C (untagged) - Homo sapiens phosphodiesterase 1C, calmodulin-dependent 70kDa (PDE1C), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PDE1C
• Synonyms: cam-PDE 1C; DFNA74; hCam-3; Hcam3
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001191059, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGTCGCCAACCAAGGAGATTGAAGAATTTGAGAGCAACTCTCTGAAATACCTGCAACCGGAACAGA
  TCGAGAAAATCTGGCTTCGGCTCCGCGGGCTGAGGAAATATAAGAAAACGTCCCAGAGATTACGGTCTTT
  GGTCAAACAATTAGAGAGAGGGGAAGCTTCAGTGGTAGATCTTAAGAAGAATTTGGAATATGCAGCCACA
  GTGCTTGAATCTGTGTATATTGATGAAACAAGGAGACTCCTGGATACAGAGGATGAGCTCAGTGACATTC
  AGTCAGATGCTGTGCCTTCTGAGGTCCGAGACTGGCTGGCCTCCACCTTCACGCGGCAGATGGGGATGAT
  GCTCAGGAGGAGCGACGAGAAGCCCCGGTTCAAGAGCATCGTTCACGCAGTGCAGGCTGGGATATTTGTG
  GAGAGAATGTATAGACGGACATCAAACATGGTTGGACTGAGCTATCCACCAGCTGTTATTGAGGCATTAA
  AGGATGTGGACAAGTGGTCCTTTGACGTCTTTTCCCTCAATGAGGCCAGTGGGGATCATGCACTGAAATT
  TATTTTCTATGAACTACTCACACGTTATGATCTGATCAGCCGTTTCAAGATCCCCATTTCTGCACTTGTC
  TCATTTGTGGAGGCCCTGGAAGTGGGATACAGCAAGCACAAAAATCCTTACCATAACTTAATGCACGCTG
  CCGATGTTACACAGACAGTGCATTACCTCCTCTATAAGACAGGAGTGGCGAACTGGCTGACGGAGCTGGA
  GATCTTTGCTATAATCTTCTCAGCTGCCATCCATGACTACGAGCATACCGGAACCACCAACAATTTCCAC
  ATTCAGACTCGGTCTGATCCAGCTATTCTGTATAATGACAGATCTGTACTGGAGAATCACCATTTAAGTG
  CAGCTTATCGCCTTCTGCAAGATGACGAGGAAATGAATATTTTGATTAACCTCTCAAAGGATGACTGGAG
  GGAGTTTCGAACCTTGGTAATTGAAATGGTGATGGCCACAGATATGTCTTGTCACTTCCAACAAATCAAA
  GCAATGAAGACTGCTCTGCAGCAGCCAGAAGCCATTGAAAAGCCAAAAGCCTTATCCCTTATGCTGCATA
  CAGCAGATATTAGCCATCCAGCAAAAGCATGGGACCTCCATCATCGCTGGACAATGTCACTCCTGGAGGA
  GTTCTTCAGACAGGGTGACAGAGAAGCAGAGCTGGGGCTGCCTTTTTCTCCTCTGTGTGACCGAAAGTCC
  ACTATGGTTGCTCAGTCACAAGTAGGTTTCATTGATTTCATCGTGGAACCCACCTTCACTGTGCTTACGG
  ACATGACCGAGAAGATTGTGAGTCCATTAATCGATGAAACCTCTCAAACTGGTGGGACAGGACAGAGGCG
  TTCGAGTTTGAATAGCATCAGCTCGTCAGATGCCAAGCGATCAGGTGTCAAGACCTCTGGTTCAGAGGGA
  AGTGCCCCGATCAACAATTCTGTCATCTCCGTTGACTATAAGAGCTTTAAAGCTACTTGGACGGAAGTGG
  TGCACATCAATCGGGAGAGATGGAGGGCCAAGGTACCCAAAGAGGAGAAGGCCAAGAAGGAAGCAGAGGA
  AAAGGCTCGCCTGGCCGCAGAGGAGCAGCAAAAGGAAATGGAAGCCAAAAGCCAGGCTGAAGAAGGCGCA
  TCTGGCAAAGCTGAGAAAAAGACGTCTGGAGAAACTAAGAATCAAGTCAATGGAACACGGGCAAACAAAA
  GTGACAACCCTCGTGGGAAAAACTCCAAAGCCGAGAAGTCATCAGGAGAACAGCAACAGAATGGTGACTT
  CAAAGATGGTAAAAATAAGACAGACAAGAAGGATCACTCTAACATCGGAAATGATTCAAAGAAAACAGAT
  GGCACAAAACAGCGTTCTCACGGCTCACCAGCCCCAAGCACCAGCTCCACGTGTCGCCTTACGTTGCCAG
  TCATCAAGCCTCCTTTGCGTCATTTTAAACGCCCTGCTTACGCATCTAGCTCCTATGCACCTTCAGTCTC
  AAAGAAAACTGATGAGCATCCTGCAAGGTACAAGATGCTGGATCAGAGGATCAAAATGAAAAAGATTCAG
  AACATCTCACATAACTGGAACAGAAAATAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001191059
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001191059.1, NP_001177988.1
• RefSeq Size: 2888 bp
• RefSeq ORF: 2130 bp
• Locus ID: 5137
• Cytogenetics: 7p14.3
• Protein Families: Druggable Genome
• Protein Pathways: Calcium signaling pathway, Olfactory transduction, Progesterone-mediated oocyte maturation, Purine metabolism
• Gene Summary: 'This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]'
  Transcript Variant: This variant (5) differs in the 5' UTR and has multiple coding region differences, compared to variant 3. These differences result in an isoform (2) with a distinct N-terminus, compared to isoform 3. Variants 2 and 5 encode the same protein. Isoform 2 is also known as HCam-3A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.