EPLIN (LIMA1) (NM_001243775) Human Untagged Clone

CAT#: SC330181

LIMA1 (untagged) - Homo sapiens LIM domain and actin binding 1 (LIMA1), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LIMA1
• Synonyms: EPLIN; LDLCQ8; SREBP3
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001243775, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGCAAAAGGAGAATGTGCCCCCAGGTCCTGAGGTCTGCATCACCCATCAGGAAGGGGAAAAGATTT
  CTGCAAATGAGAATAGCCTGGCAGTCCGTTCCACCCCTGCCGAAGATGACTCCCGTGACTCCCAGGTTAA
  GAGTGAGGTTCAACAGCCTGTCCATCCCAAGCCACTAAGTCCAGATTCCAGAGCCTCCAGTCTTTCTGAA
  AGTTCTCCTCCCAAAGCAATGAAGAAGTTTCAGGCACCTGCAAGAGAGACCTGCGTGGAATGTCAGAAGA
  CAGTCTATCCAATGGAGCGTCTCTTGGCCAACCAGCAGGTGTTTCACATCAGCTGCTTCCGTTGCTCCTA
  TTGCAACAACAAACTCAGTCTAGGAACATATGCATCTTTACATGGAAGAATCTATTGTAAGCCTCACTTC
  AATCAACTCTTTAAATCTAAGGGCAACTATGATGAAGGCTTTGGGCACAGACCACACAAGGATCTATGGG
  CAAGCAAAAATGAAAACGAAGAGATTTTGGAGAGACCAGCCCAGCTTGCAAATGCAAGGGAGACCCCTCA
  CAGCCCAGGGGTAGAAGATGCCCCTATTGCTAAGGTGGGTGTCCTGGCTGCAAGTATGGAAGCCAAGGCC
  TCCTCTCAGCAGGAGAAGGAAGACAAGCCAGCTGAAACCAAGAAGCTGAGGATCGCCTGGCCACCCCCCA
  CTGAACTTGGAAGTTCAGGAAGTGCCTTGGAGGAAGGGATCAAAATGTCAAAGCCCAAATGGCCTCCTGA
  AGACGAAATCAGCAAGCCCGAAGTTCCTGAGGATGTCGATCTAGATCTGAAGAAGCTAAGACGATCTTCT
  TCACTGAAGGAAAGAAGCCGCCCATTCACTGTAGCAGCTTCATTTCAAAGCACCTCTGTCAAGAGCCCAA
  AAACTGTGTCCCCACCTATCAGGAAAGGCTGGAGCATGTCAGAGCAGAGTGAAGAGTCTGTGGGTGGAAG
  AGTTGCAGAAAGGAAACAAGTGGAAAATGCCAAGGCTTCTAAGAAGAATGGGAATGTGGGAAAAACAACC
  TGGCAAAACAAAGAATCTAAAGGAGAGACAGGGAAGAGAAGTAAGGAAGGTCATAGTTTGGAGATGGAGA
  ATGAGAATCTTGTAGAAAATGGTGCAGACTCCGATGAAGATGATAACAGCTTCCTCAAACAACAATCTCC
  ACAAGAACCCAAGTCTCTGAATTGGTCGAGTTTTGTAGACAACACCTTTGCTGAAGAATTCACTACTCAG
  AATCAGAAATCCCAGGATGTGGAACTCTGGGAGGGAGAAGTGGTCAAAGAGCTCTCTGTGGAAGAACAGA
  TAAAGAGAAATCGGTATTATGATGAGGATGAGGATGAAGAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001243775
• ORF Size: 1374 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001243775.1, NP_001230704.1
• RefSeq Size: 3356
• RefSeq ORF: 1374
• Locus ID: 51474
• Gene Summary: This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (4) differs at the 5' end, and uses an alternate in-frame acceptor splice site at an internal coding exon compared to variant 1. This results in translation initiation from an in-frame downstream AUG, and an isoform (4) with a shorter N-terminus and lacking an internal aa compared to isoform 1.