DUS2L (DUS2) (NM_001271763) Human Untagged Clone

CAT#: SC330967

DUS2L (untagged) - Homo sapiens dihydrouridine synthase 2 (DUS2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DUS2
• Synonyms: DUS2L; SMM1; URLC8
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001271763, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATTTTGAATAGCCTCTCTCTGTGTTACCATAATAAGCTAATCCTGGCCCCAATGGTTCGGGTAGGGA
  CTCTTCCAATGAGGCTGCTGGCCCTGGATTATGGAGCGGACATTGTTTACTGTGAGGAGCTGATCGACCT
  CAAGATGATTCAGTGCAAGAGAGTTGTTAATGAGGTGCTCAGCACAGTGGACTTTGTCGCCCCTGATGAT
  CGAGTTGTCTTCCGCACCTGTGAAAGAGAGCAGAACAGGGTGGTCTTCCAGATGGGAGGAATGGGAGCTG
  CCCTGCTGTCAGACCCTGACAAGATTGAGAAGATCCTCAGCACTCTTGTTAAAGGGACACGCAGACCTGT
  GACCTGCAAGATTCGCATCCTGCCATCGCTAGAAGATACCCTGAGCCTTGTGAAGCGGATAGAGAGGACT
  GGCATTGCTGCCATCGCAGTTCATGGGAGGAAGCGGGAGGAGCGACCTCAGCATCCTGTCAGCTGTGAAG
  TCATCAAAGCCATTGCTGATACCCTCTCCATTCCTGTCATAGCCAACGGAGGATCTCATGACCACATCCA
  ACAGTATTCGGACATAGAGGACTTTCGACAAGCCACGGCAGCCTCTTCCGTGATGGTGGCCCGAGCAGCC
  ATGTGGAACCCATCTATCTTCCTCAAGGAGGGTCTGCGGCCCCTGGAGGAGGTCATGCAGAAATACATCA
  GATACGCGGTGCAGTATGACAACCACTACACCAACACCAAGTACTGCTTGTGCCAGATGCTACGAGAACA
  GCTGGAGTCGCCCCAGGGAAGGTTGCTCCATGCTGCCCAGTCTTCCCGGGAAATTTGTGAGGCCTTTGGC
  CTTGGTGCCTTCTATGAGGAGACCACACAGGAGCTGGATGCCCAGCAGGCCAGGCTCTCAGCCAAGACTT
  CAGAGCAGACAGGGGAGCCAGCTGAAGATACCTCTGGTGTCATTAAGATGGCTGTCAAGTTTGACCGGAG
  AGCATACCCAGCCCAGATCACCCCTAAGATGTGCCTACTAGAGTGGTGCCGGAGGGAGAAGTTGGCACAG
  CCTGTGTATGAAACGGTTCAACGCCCTCTAGATCGCCTGTTCTCCTCTATTGTCACCGTTGCTGAACAAA
  AGTATCAGTCTACCTTGTGGGACAAGTCCAAGAAACTGGCGGAGCAGGCTGCAGCCATCGTCTGTCTGCG
  GAGCCAGGGCCTCCCTGAGGGTCGGCTGGGTGAGGAGAGCCCTTCCTTGCACAAGCGAAAGAGGGAGGCT
  CCTGACCAAGACCCTGGGGGCCCCAGAGCTCAGGAGCTAGCACAACCTGGGGATCTGTGCAAGAAGCCCT
  TTGTGGCCTTGGGAAGTGGTGAAGAAAGCCCCCTGGAAGGCTGGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001271763
• ORF Size: 1377 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001271763.1, NP_001258692.1
• RefSeq Size: 2237
• RefSeq ORF: 1377
• Locus ID: 54920
• Gene Summary: This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
  Transcript Variant: This variant (3) lacks two alternate exons, resulting in the loss of an in-frame segment in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.