RGS6 (NM_001204424) Human Untagged Clone

CAT#: SC331584

RGS6 (untagged) - Homo sapiens regulator of G-protein signaling 6 (RGS6), transcript variant 10

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RGS6
• Synonyms: GAP; HA117; S914
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001204424, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTCAAGGATCCGGGGATCAAAGAGCAGTGGGGGTTGCTGACCCAGAGGAGAGTTCTCCAAACATGA
  TCGTTTACTGCAAAATTGAAGACATCATTACAAAGATGCAAGATGACAAGACAGGGGGTGTGCCCATCAG
  AACAGTCAAGAGCTTTCTCTCCAAAATCCCCAGTGTCGTCACAGGTACTGACATTGTGCAGTGGCTTATG
  AAGAACCTTTCCATTGAGGACCCAGTTGAAGCAATACACTTGGGGAGCCTTATCGCTGCCCAGGGCTACA
  TCTTTCCAATCTCAGACCATGTTCTCACCATGAAGGATGATGGCACCTTTTATCGTTTCCAGGCTCCGTA
  CTTCTGGCCTTCGAACTGCTGGGAACCTGAAAACACTGACTATGCCATCTATCTCTGTAAGAGGACAATG
  CAAAATAAAGCAAGGCTGGAACTGGCAGATTATGAAGCAGAAAACTTAGCAAGACTCCAGAGGGCCTTTG
  CGAGGAAGTGGGAATTCATCTTTATGCAAGCAGAAGCACAAGTAAAGATTGACCGGAAAAAAGACAAGAC
  AGAAAGGAAAATTTTGGATAGTCAAGAACGAGCCTTTTGGGATGTCCACAGGCCTGTGCCAGGCTGTGTG
  AACACAACAGAAATGGATATCCGAAAATGTCGACGTTTGAAGAATCCACAAAAGGTTAAAAAGTCCGTGT
  ATGGCGTGACTGAAGAGTCCCAGGCACAGAGCCCGGTGCATGTACTCAGCCAACCAATCAGGAAAACAAC
  AAAAGAGGACATCCGGAAACAGATAACATTTTTGAACGCACAGATCGACAGACATTGTTTGAAAATGTCC
  AAAGTGGCTGAAAGTTTAATTGCCTACACGGAACAATATGTGGAATATGACCCTTTGATAACACCAGCTG
  AGCCATCCAACCCTTGGATCAGCGATGACGTTGCTTTGTGGGACATAGAGATGAGCAAAGAGCCCAGCCA
  ACAGCGAGTAAAAAGATGGGGCTTCTCTTTCGATGAGATATTGAAGGACCAGGTGGGGCGGGACCAGTTT
  CTACGATTCCTGGAGTCCGAATTCAGTTCAGAAAACCTCAGGTTCTGGCTGGCTGTCCAAGATCTTAAGA
  AACAACCCCTACAGGATGTGGCCAAGAGGGTAGAAGAAATCTGGCAAGAGTTTCTGGCTCCAGGGGCTCC
  AAGTGCAATCAACCTGGATTCTCACAGCTATGAGATAACCAGTCAAAATGTCAAAGATGGAGGGAGATAT
  ACATTTGAAGACGCCCAGGAGCACATCTACAAGCTGATGAAGAGTGACAGCTATGCCCGCTTCCTCCGGT
  CAAATGCTTACCAGGATTTGCTGCTGGCCAAGAAGAAGCCAGAAAGTGAGCAAGGTCGTAGAACTTCCCT
  AGAAAAGTTCACTCGCAGTGTGGGAAAGTCGCTGGCGGGCAAGCGCCTCACGGGCCTGATGCAGTCCTCC
  TGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001204424
• ORF Size: 1473 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001204424.1, NP_001191353.1
• RefSeq Size: 6073
• RefSeq ORF: 1473
• Locus ID: 9628
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known. [provided by RefSeq, Mar 2011]
  Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 1. Variants 1 and 10 encode the same isoform (1).