ERBIN (NM_001253698) Human Untagged Clone
CAT#: SC332217
ERBB2IP (untagged) - Homo sapiens erbb2 interacting protein (ERBB2IP), transcript variant 4
"NM_001253698" in other vectors (2)
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | ERBIN |
Synonyms | ERBB2IP; HEL-S-78; LAP2 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_001253698, the custom clone sequence may differ by one or more nucleotides
ATGACTACAAAACGAAGTTTGTTTGTGCGGTTGGTACCATGTCGCTGTCTACGAGGGGAAGAGGAGACTG TCACTACTCTTGATTATTCTCATTGCAGCTTAGAACAAGTTCCGAAAGAGATTTTTACTTTTGAAAAAAC CTTGGAGGAACTCTATTTAGATGCTAATCAGATTGAAGAGCTTCCAAAGCAACTTTTTAACTGTCAGTCT TTACACAAACTGAGTTTGCCAGACAATGATTTAACAACGTTACCAGCATCCATTGCAAACCTTATTAATC TCAGGGAACTGGATGTCAGCAAGAATGGAATACAGGAGTTTCCAGAAAATATAAAAAATTGTAAAGTTTT GACAATTGTGGAGGCCAGTGTAAACCCTATTTCCAAGCTCCCTGATGGATTTTCTCAGCTGTTAAACCTA ACCCAGTTGTATCTGAATGATGCTTTTCTTGAGTTCTTGCCAGCAAATTTTGGCAGATTAACTAAACTCC AAATATTAGAGCTTAGAGAAAACCAGTTAAAAATGTTGCCTAAAACTATGAATAGACTGACCCAGCTGGA AAGACTGGATTTGGGAAGTAACGAATTCACGGAAGTGCCTGAAGTACTTGAGCAACTAAGTGGATTGAAA GAGTTTTGGATGGATGCTAATAGACTGACTTTTATTCCAGGGTTTATTGGTAGTTTGAAACAGCTCACAT ATTTGGATGTTTCTAAAAATAATATTGAAATGGTTGAAGAAGGAATTTCAACATGTGAAAACCTTCAAGA CCTCCTATTATCAAGCAATTCACTTCAGCAGCTTCCTGAGACTATTGGTTCGTTGAAGAATATAACAACG CTTAAAATAGATGAAAACCAGTTAATGTATCTGCCAGACTCTATAGGAGGGTTAATATCAGTAGAAGAAC TGGATTGTAGTTTCAATGAAGTTGAAGCTTTGCCTTCATCTATTGGGCAGCTTACTAACTTAAGAACTTT TGCTGCTGATCATAATTACTTACAGCAGTTGCCCCCAGAGATTGGAAGCTGGAAAAATATAACTGTGCTG TTTCTCCATTCCAATAAACTTGAGACACTTCCAGAGGAAATGGGTGATATGCAAAAATTAAAAGTCATTA ATTTAAGTGATAATAGATTAAAGAATTTACCCTTTAGCTTTACAAAGCTACAGCAATTGACAGCTATGTG GCTCTCAGATAATCAGTCCAAACCCCTGATACCTCTTCAAAAAGAAACTGATTCAGAGACCCAGAAAATG GTGCTTACCAACTACATGTTCCCTCAACAGCCAAGGACTGAGGATGTTATGTTTATATCAGATAATGAAA GTTTTAACCCTTCATTGTGGGAGGAACAGAGGAAACAGCGGGCTCAAGTTGCATTTGAATGTGATGAAGA CAAAGATGAAAGGGAGGCACCTCCCAGGGAGGGAAATTTAAAAAGATATCCAACACCATACCCAGATGAG CTTAAGAATATGGTCAAAACTGTTCAAACCATTGTACATAGATTAAAAGATGAAGAGACCAATGAAGACT CAGGAAGAGATTTGAAACCACATGAAGATCAACAAGATATAAATAAAGATGTGGGTGTGAAGACCTCAGA AAGTACTACTACAGTAAAAAGCAAAGTTGATGAAAGAGAAAAATATATGATAGGAAACTCTGTACAGAAG ATCAGTGAACCTGAAGCTGAGATTAGTCCTGGGAGTTTACCAGTGACTGCAAATATGAAAGCCTCTGAGA ACTTGAAGCATATTGTTAACCATGATGATGTTTTTGAGGAATCTGAAGAACTTTCTTCTGATGAAGAGAT GAAAATGGCGGAGATGCGACCACCATTAATTGAAACCTCTATTAACCAGCCAAAAGTCGTAGCACTTAGT AATAACAAAAAAGATGATACAAAGGAAACAGATTCTTTATCAGATGAAGTTACACACAATAGCAATCAGA ATAACAGCAATTGTTCTTCTCCATCTCGGATGTCTGATTCAGTTTCTCTTAATACTGATAGTAGTCAAGA CACCTCACTCTGCTCTCCAGTGAAACAAACTCATATTGATATTAATTCCAAAATCAGGCAAGAAGATGAA AATTTTAACAGCCTTTTACAAAATGGAGATATTTTAAACAGTTCAACAGAGGAAAAGTTCAAAGCTCATG ATAAAAAAGATTTTAACTTACCTGAATATGATTTGAATGTTGAAGAGCGATTAGTTCTAATTGAGAAAAG TGTTGACTCAACAGCCACAGCTGATGACACTCACAAATTAGATCATATCAATATGAATCTTAATAAACTT ATAACTAATGATACATTTCAACCAGAGATCATGGAAAGATCAAAAACACAGGATATTGTGCTTGGAACAA GCTTTTTAAGCATTAATTCTAAAGAGGAAACTGAGCACTTGGAAAATGGAAACAAGTATCCTAATTTGGA ATCCGTAAATAAGGTAAATGGACATTCTGAGGAAACTTCCCAGTCTCCTAATAGGACTGAACCACATGAC AGTGATTGTTCTGTTGACTTAGGTATTTCCAAAAGCACTGAAGATCTCTCCCCTCAGAAAAGTGGTCCAG TTGGATCTGTTGTGAAATCTCATAGCATAACTAATATGGAGATTGGAGGGCTAAAAATCTATGATATTCT TAGTGATAATGGACCTCAGCAGCCAAGTACAACCGTTAAAATCACATCTGCTGTTGATGGAAAAAATATA GTCAGGAGCAAGTCTGCCACACTGTTGTATGATCAACCATTGCAGGTATTTACTGGTTCTTCCTCATCTT CTGATTTAATATCAGGAACAAAGGCAATTTTCAAGTTTGATTCAAATCATAATCCCGAAGAGCCAAATAT AATAAGAGGCCCCACAAGTGGCCCACAATCTGCACCTCAAATATATGGTCCTCCACAGTATAATATCCAA TACAGTAGCAGTGCTGCAGTCAAAGACACTTTGTGGCACTCCAAACAAAATCCCCAAATAGACCATGCCA GTTTTCCTCCTCAGCTCCTTCCTAGATCAGAGAGCACAGAAAATCAAAGTTATGCTAAACATTCTGCCAA TATGAATTTCTCTAATCATAACAATGTTCGAGCTAATACTGCATACCATTTACATCAGAGACTTGGCCCA GCAAGACATGGGGAAATGTGGGCCATCTCACCAAACGACCGACTTATTCCTGCAGTAACTCGAAGTACAA TCCAGCGACAAAGTAGTGTGTCCTCCACAGCCTCTGTAAATCTTGGTGATCCAGGCTCTACAAGGCGGGC TCAGATTCCTGAAGGAGATTATTTATCATACAGAGAGTTCCACTCAGCGGGAAGAACTCCTCCAATGATG CCAGGATCACAGAGACCCCTTTCTGCACGAACATACAGCATAGATGGTCCAAATGCATCAAGACCTCAGA GTGCTCGACCCTCTATTAATGAAATACCAGAGAGAACTATGTCAGTTAGTGATTTCAATTATTCACGGAC TAGTCCTTCAAAAAGACCAAATGCAAGGGTTGGTTCTGAGCATTCTTTATTAGATCCTCCAGGAAAAAGT AAAGTTCCTCGTGACTGGAGAGAACAAGTACTTCGACATATTGAAGCCAAAAAGTTAGAAAAGATGCCTT TGAGTAATGGACAGATGGGCCAGCCTCTCAGGCCTCAGGCAAATTATAGTCAAATACATCACCCCCCTCA GGCATCTGTGGCAAGGCATCCCTCTAGAGAACAACTAATTGATTACTTGATGCTGAAAGTGGCCCACCAG CCTCCATATACACAGCCCCATTGTTCTCCTAGACAAGGCCATGAACTGGCAAAACAAGAGATTCGAGTGA GGGTTGAAAAGGATCCAGAACTTGGATTTAGCATATCAGGTGGTGTCGGGGGTAGAGGAAACCCATTCAG ACCTGATGATGATGCTAATGGCTACAGTTTTATAAATATTGAACATGGACAAGCAGTGTCCTTGCTAAAA ACTTTCCAGAATACAGTTGAACTCATCATTGTACGAGAAGTTTCCTCATAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001253698 |
ORF Size | 4041 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Reference Data | |
RefSeq | NM_001253698.1, NP_001240627.1 |
RefSeq Size | 6844 |
RefSeq ORF | 4041 |
Locus ID | 55914 |
Protein Families | Druggable Genome |
Protein Pathways | NOD-like receptor signaling pathway |
Gene Summary | This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] Transcript Variant: This variant (4) lacks two exons in the 3' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (4) is shorter than isoform 1. |
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