NDRG1 (NM_001258432) Human Untagged Clone
CAT#: SC332706
NDRG1 (untagged) - Homo sapiens N-myc downstream regulated 1 (NDRG1), transcript variant 3
"NM_001258432" in other vectors (2)
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | NDRG1 |
Synonyms | CAP43; CMT4D; DRG-1; DRG1; GC4; HMSNL; NDR1; NMSL; PROXY1; RIT42; RTP; TARG1; TDD5 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_001258432, the custom clone sequence may differ by one or more nucleotides
ATGAACCACAAAACCTGCTACAACCCCCTCTTCAACTACGAGGACATGCAGGAGATCACCCAGCACTTTG CCGTCTGCCACGTGGACGCCCCTGGCCAGCAGGACGGCGCAGCCTCCTTCCCCGCAGGGTACATGTACCC CTCCATGGATCAGCTGGCTGAAATGCTTCCTGGAGTCCTTCAACAGTTTGGGCTGAAAAGCATTATTGGC ATGGGAACAGGAGCAGGCGCCTACATCCTAACTCGATTTGCTCTAAACAACCCTGAGATGGTGGAGGGCC TTGTCCTTATCAACGTGAACCCTTGTGCGGAAGGCTGGATGGACTGGGCCGCCTCCAAGATCTCAGGATG GACCCAAGCTCTGCCGGACATGGTGGTGTCCCACCTTTTTGGGAAGGAAGAAATGCAGAGTAACGTGGAA GTGGTCCACACCTACCGCCAGCACATTGTGAATGACATGAACCCCGGCAACCTGCACCTGTTCATCAATG CCTACAACAGCCGGCGCGACCTGGAGATTGAGCGACCAATGCCGGGAACCCACACAGTCACCCTGCAGTG CCCTGCTCTGTTGGTGGTTGGGGACAGCTCGCCTGCAGTGGATGCCGTGGTGGAGTGCAACTCAAAATTG GACCCAACAAAGACCACTCTCCTCAAGATGGCGGACTGTGGCGGCCTCCCGCAGATCTCCCAGCCGGCCA AGCTCGCTGAGGCCTTCAAGTACTTCGTGCAGGGCATGGGATACATGCCCTCGGCTAGCATGACCCGCCT GATGCGGTCCCGCACAGCCTCTGGTTCCAGCGTCACTTCTCTGGATGGCACCCGCAGCCGCTCCCACACC AGCGAGGGCACCCGAAGCCGCTCCCACACCAGCGAGGGCACCCGCAGCCGCTCGCACACCAGCGAGGGGG CCCACCTGGACATCACCCCCAACTCGGGTGCTGCTGGGAACAGCGCCGGGCCCAAGTCCATGGAGGTCTC CTGCTAG |
Restriction Sites | SgfI-MluI |
ACCN | NM_001258432 |
ORF Size | 987 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Reference Data | |
RefSeq | NM_001258432.1, NP_001245361.1 |
RefSeq Size | 3006 |
RefSeq ORF | 987 |
Locus ID | 10397 |
Gene Summary | This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] Transcript Variant: This variant (3) lacks two consecutive internal exons and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. |
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