BORIS (CTCFL) (NM_001269049) Human Untagged Clone

CAT#: SC332902

CTCFL (untagged) - Homo sapiens CCCTC-binding factor (zinc finger protein)-like (CTCFL), transcript variant 11

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CTCFL
• Synonyms: BORIS; CT27; CTCF-T; dJ579F20.2; HMGB1L1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001269049, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCAGGAGATGAAAGAAGTGACGAAATTGTTCTCACAGTTTCAAATTCAAATGTGGAAGAACAAGAGG
  ATCAACCTACAGCTGGTCAAGCAGATGCTGAAAAGGCCAAATCTACAAAAAATCAAAGAAAGACAAAGGG
  AGCAAAAGGAACCTTCCACTGTGATGTCTGCATGTTCACCTCTTCTAGAATGTCAAGTTTTAATCGTCAT
  ATGAAAACTCACACCAGTGAGAAGCCTCACCTGTGTCACCTCTGCCTGAAAACCTTCCGTACGGTCACTC
  TGCTGCGGAACCATGTTAACACCCACACAGGAACCAGGCCCTACAAGTGTAACGACTGCAACATGGCATT
  TGTCACCAGTGGAGAACTCGTCCGACACAGGCGCTATAAACATACTCATGAGAAACCCTTTAAATGTTCC
  ATGTGCAAGTATGCCAGTGTGGAGGCAAGTAAATTGAAGCGCCATGTCCGATCCCACACTGGGGAGCGCC
  CCTTTCAGTGTTGCCAGTGCAGCTATGCCAGCAGAGATACCTACAAGCTGAAACGCCACATGAGAACGCA
  CTCAGGTGAGAAGCCTTACGAATGCCACATCTGCCACACCCGCTTCACCCAGAGCGGGACCATGAAAATA
  CATATTCTGCAGAAACACGGCGAAAATGTCCCCAAATACCAGTGTCCCCATTGTGCCACCATCATTGCAC
  GGAAAAGCGACCTACGTGTGCATATGCGCAACTTGCATGCTTACAGCGCTGCAGAGCTGAAATGCCGCTA
  CTGTTCTGCTGTCTTCCATGAACGCTATGCCCTCATTCAGCACCAGAAAACTCATAAGAATGAGAAGAGG
  TTCAAGTGCAAACACTGCAGTTATGCCTGCAAGCAGGAACGTCATATGACCGCTCACATTCGTACCCACA
  CTGGAGAGAAACCATTCACCTGCCTTTCTTGCAATAAATGTTTCCGACAGAAGCAACTTCTAAACGCTCA
  CTTCAGGAAATACCACGATGCAAATTTCATCCCGACTGTTTACAAATGCTCCAAGTGTGGCAAAGGCTTT
  TCCCGCTGGATTAACCTGCACAGACATTCGGAGAAGTGTGGATCAGGGGAAGCAAAGTCGGCTGCTTCAG
  GAAAGGGAAGAAGAACAAGAAAGAGGAAGCAGACCATCCTGAAGGAAGCCACAAAGGGTCAGAAGGAAGC
  TGCGAAGGGATGGAAGGAAGCCGCGAACGGAGACGGTGTGATCTCAGCTCACCGCAACCTCTGCCTCCTG
  GGTTCAAGTGATTCTCATGCCTCAGTCTCCGGAGCTGGGATTACAGATGCCCGCCACCACGCCTGGCTAA
  TTGTTCTATTATTTTTAGTAGAGATGGGGTTTTACCATGTCTCTCACTCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001269049
• ORF Size: 1383 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001269049.1, NP_001255978.1
• RefSeq Size: 2288
• RefSeq ORF: 1383
• Locus ID: 140690
• Protein Families: Transcription Factors
• Gene Summary: CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
  Transcript Variant: This variant (11, also kown as B3) differs in the 5' and 3' UTRs and has multiple coding region differences, compared to variant 1. The translation initiation is at a downstream in-frame AUG and the resulting isoform (9, also known as B3) has a shorter N-terminus and a shorter and distinct C-terminus, compared to isoform 1.