PPP3CB (NM_001289969) Human Untagged Clone

CAT#: SC335939

PPP3CB (untagged) - Human protein phosphatase 3, catalytic subunit, beta isozyme (PPP3CB), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPP3CB
• Synonyms: CALNA2; CALNB; CNA2; PP2Bbeta
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001289969, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATAGAAGTAGAAGCTCCAATCACAGTGTGTGGTGACATCCATGGCCAATTTTTTGATCTGATGAAAC
  TTTTTGAAGTAGGAGGATCACCTGCTAATACACGATACCTTTTTCTTGGCGATTATGTGGACAGAGGTTA
  TTTTAGTATAGAGTGTGTCTTATATTTATGGGTTCTGAAGATTCTATACCCAAGCACATTATTTCTTCTG
  AGAGGCAACCATGAATGCAGACACCTTACTGAATATTTTACCTTTAAGCAGGAATGTAAAATTAAGTATT
  CGGAAAGAGTCTATGAAGCTTGTATGGAAGCTTTTGATAGTTTGCCTCTTGCTGCACTTTTAAACCAACA
  GTTTCTTTGTGTTCATGGTGGACTTTCACCAGAAATACACACACTGGATGATATTAGGAGATTAGATAGA
  TTCAAAGAGCCACCTGCATTTGGACCAATGTGTGACTTGTTATGGTCCGATCCTTCTGAAGATTTTGGAA
  ATGAAAAATCACAGGAACATTTTAGTCACAATACAGTTCGAGGATGTTCTTATTTTTATAACTATCCAGC
  AGTGTGTGAATTTTTGCAAAACAATAATTTGTTATCGATTATTAGAGCTCATGAAGCTCAAGATGCAGGC
  TATAGAATGTACAGAAAAAGTCAAACTACAGGGTTCCCTTCATTAATAACAATTTTTTCGGCACCTAATT
  ACTTAGATGTCTACAATAATAAAGCTGCTGTATTAAAGTATGAAAATAATGTGATGAATATTCGACAGTT
  TAACTGTTCTCCACATCCTTACTGGTTGCCTAATTTTATGGATGTCTTCACGTGGTCTTTACCGTTTGTT
  GGAGAAAAAGTGACAGAAATGTTGGTAAATGTTCTGAGTATTTGCTCTGATGATGAACTAATGACTGAAG
  GTGAAGACCAGTTTGATGGTTCAGCTGCAGCCCGGAAAGAAATCATAAGAAACAAAATTCGAGCAATTGG
  CAAGATGGCAAGAGTCTTCTCTGTTCTCAGGGAGGAGAGTGAAAGTGTGCTGACACTCAAGGGCCTGACT
  CCCACAGGGATGTTGCCTAGTGGAGTGTTAGCTGGAGGACGGCAGACCCTGCAAAGTGGTAATGATGTTA
  TGCAACTTGCTGTGCCTCAGATGGACTGGGGCACACCTCACTCTTTTGCTAACAATTCACATAATGCATG
  CAGGGAATTCCTTCTGTTTTTTAGTTCCTGTCTCAGCAGCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001289969
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001289969.1, NP_001276898.1
• RefSeq Size: 2581 bp
• RefSeq ORF: 1233 bp
• Locus ID: 5532
• Cytogenetics: 10q22.2
• Protein Families: Druggable Genome, Phosphatase, Transcription Factors
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Axon guidance, B cell receptor signaling pathway, Calcium signaling pathway, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
• Gene Summary: ''
  Transcript Variant: This variant (5) has multiple differences in the coding region, one of which results in a frameshift and early stop codon, compared to variant 1. The resulting protein (isoform e) has a distinct C-terminus and is shorter than isoform a.