EHD1 (NM_001282445) Human Untagged Clone

CAT#: SC336741

EHD1 (untagged) - Human EH-domain containing 1 (EHD1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EHD1
• Synonyms: H-PAST; HPAST1; PAST; PAST1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282445, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAACAGCCAGGAACTGCAGCCAGCCCCGTGTCCGGCAGTATGTTCAGCTGGGTCAGCAAGGATGCCC
  GCCGCAAGAAGGAGCCGGAGCTCTTCCAGACGGTGGCCGAGGGGCTGCGGCAGCTGTACGCGCAGAAGCT
  GCTACCCCTGGAGGAGCACTACCGCTTCCACGAGTTCCACTCGCCCGCGCTGGAGGACGCTGACTTCGAC
  AACAAGCCTATGGTGCTCCTCGTGGGGCAGTACAGCACGGGCAAGACCACCTTCATCCGACACCTGATCG
  AGCAGGACTTCCCGGGGATGCGCATCGGGCCCGAGCCCACCACCGACTCCTTCATCGCCGTCATGCACGG
  CCCCACTGAGGGCGTGGTGCCGGGCAACGCGCTCGTGGTGGACCCGCGGCGCCCCTTCCGCAAGCTCAAC
  GCGTTTGGCAACGCTTTCCTCAACAGGTTCATGTGTGCCCAGCTGCCCAACCCCGTCCTGGACAGCATCA
  GCATCATCGACACCCCCGGGATCCTGTCTGGAGAGAAGCAGCGGATCAGCAGAGGCTATGACTTTGCAGC
  CGTCCTGGAGTGGTTCGCGGAGCGTGTGGACCGCATCATCCTGCTCTTCGACGCCCACAAGCTGGACATC
  TCCGATGAGTTCTCGGAAGTGATCAAGGCTCTGAAGAACCATGAGGACAAGATCCGCGTGGTGCTGAACA
  AGGCAGACCAGATCGAGACGCAGCAGCTGATGCGGGTGTACGGGGCCCTCATGTGGTCCCTGGGCAAGAT
  CATCAACACCCCCGAGGTGGTCAGGGTCTACATCGGCTCCTTCTGGTCCCACCCGCTCCTCATCCCCGAC
  AACCGCAAGCTCTTTGAGGCCGAGGAGCAGGACCTCTTCAAGGACATCCAGTCACTGCCCCGAAACGCCG
  CCCTCAGGAAGCTCAATGACCTGATCAAGCGGGCACGGCTGGCCAAGGTTCACGCCTACATCATCAGCTC
  CCTCAAGAAAGAGATGCCCAATGTCTTTGGTAAAGAGAGCAAAAAGAAAGAGCTGGTGAACAACCTGGGA
  GAGATCTACCAGAAGATTGAGCGCGAGCACCAGATCTCCCCTGGGGACTTCCCGAGCCTCCGCAAGATGC
  AGGAACTCCTGCAGACCCAGGACTTCAGCAAGTTCCAGGCGCTGAAGCCCAAGCTGCTGGACACGGTGGA
  TGACATGCTGGCCAACGACATCGCGCGGCTGATGGTGATGGTGCGGCAGGAGGAGTCCCTGATGCCTTCC
  CAGGTGGTCAAGGGCGGCGCCTTTGACGGCACCATGAACGGGCCGTTCGGGCACGGCTACGGCGAGGGGG
  CCGGCGAGGGCATCGACGACGTGGAGTGGGTGGTGGGCAAGGACAAGCCCACCTACGACGAGATCTTCTA
  CACGCTGTCCCCTGTCAACGGCAAGATCACGGGCGCCAACGCCAAGAAGGAGATGGTGAAGTCCAAGCTC
  CCCAACACCGTGCTAGGGAAGATCTGGAAGCTGGCCGACGTGGACAAGGACGGGCTGCTGGACGACGAGG
  AGTTCGCGCTGGCCAACCACCTCATCAAGGTCAAGCTGGAGGGCCACGAGCTGCCCGCCGACCTGCCCCC
  GCACCTGGTGCCGCCCTCCAAGCGCAGACATGAGTGA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001282445
• ORF Size: 1647 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282445.1, NP_001269374.1
• RefSeq Size: 3354
• RefSeq ORF: 1647
• Locus ID: 10938
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis
• Gene Summary: This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (3) lacks an internal exon in the 5' region, which results in an upstream in-frame AUG start codon, compared to variant 1. The resulting isoform (2) has a longer N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.