EYA4 (NM_001301012) Human Untagged Clone

CAT#: SC336883

EYA4 (untagged) - Human EYA transcriptional coactivator and phosphatase 4 (EYA4), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EYA4
• Synonyms: CMD1J; DFNA10
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001301012, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAAGACTCCCAGGATTTAAATGAACAATCAGTAAAGAAAACGTGCACAGAATCAGATGTTTCACAAT
  CTCAGAATTCCAGGTCTATGGAAATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATAC
  TCCAGGTAGCTCCAAACTGGAAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGACAGGAGTA
  ATTACAAGTAGTGGCTACAGCCCCAGATCAGCACATCAGTATTCCCCACAGCTGTATCCTTCCAAGCCCT
  ATCCACACATTCTTTCTACACCAGCAGCTCAAACAATGTCTGCCTATGCAGGCCAGACTCAGTATTCGGG
  GATGCAGCAGCCAGCCGTCTACACAGCCTACTCACAGACAGGACAGCCCTACAGCTTGCCCACTTACGAT
  TTGGGTGTGATGTTGCCAGCCATCAAGACAGAGAGTGGACTTTCCCAAACTCAGTCCCCATTACAGAGTG
  GCTGCCTCAGTTACAGCCCAGGGTTCTCTACCCCACAGCCAGGCCAGACACCTTATTCTTACCAAATGCC
  AGGTTCTAGTTTTGCACCATCATCTACTATTTATGCAAATAATTCAGTTTCCAATTCAACGAATTTCAGT
  GGTTCACAACAGGATTATCCATCCTATACAGCCTTTGGCCAAAACCAGTATGCACAGTATTATTCAGCAT
  CAACGTATGGAGCGTATATGACATCGAATAACACAGCCGATGGCACACCCTCTTCAACCTCTACTTATCA
  GTTGCAGGAATCTCTCCCAGGACTGACTAACCAACCAGGAGAGTTCGATACCATGCAGAGTCCCTCCACA
  CCCATCAAAGATCTTGATGAGAGAACCTGTAGGAGTTCTGGGTCAAAGTCCAGAGGAAGAGGCCGGAAAA
  ATAATCCCTCCCCGCCTCCTGATAGTGACCTGGAGCGTGTGTTTGTCTGGGATTTGGATGAAACCATCAT
  TGTTTTTCACTCACTGCTCACCGGGTCTTATGCACAGAAGTATGGCAAGGATCCCCCCATGGCTGTAACC
  CTTGGACTCCGCATGGAAGAAATGATTTTTAATCTTGCTGATACTCATTTGTTTTTTAATGATTTAGAGG
  AGTGTGATCAAGTTCATATAGATGATGTTTCCTCTGATGATAATGGGCAGGACTTAAGTACCTACAGTTT
  TGCAACTGATGGCTTCCATGCAGCTGCAAGTAGTGCAAACCTTTGTTTGCCAACAGGTGTAAGAGGAGGG
  GTTGACTGGATGAGGAAGTTGGCTTTTCGTTACAGAAGAGTAAAAGAATTATATAACACCTACAAGAACA
  ACGTTGGAGGACTCCTTGGCCCTGCCAAGAGGGATGCCTGGCTACAGTTAAGGGCAGAGATTGAAGGTCT
  GACAGATTCCTGGCTAACAAATGCACTTAAGTCTTTATCAATTATTAGCACTAGGAGTAACTGCATAAAT
  GTCTTGGTAACGACAACTCAACTGATCCCAGCACTTGCGAAGGTTCTACTCTATAGTTTAGGAGGTGCTT
  TCCCCATTGAGAATATTTACAGTGCAACTAAAATAGGCAAGGAAAGCTGTTTTGAGCGTATAGTGTCCAG
  ATTTGGCACTAACATAACTTATGTTGTGATTGGAGATGGCCGAGATGAGGAGCATGCCGCTAACCAGCAC
  AACATGCCCTTCTGGAGGATATCCAGTCACTCAGACCTCCTGGCTCTCCACCAAGCACTGGAATTAGAGT
  ATTTGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001301012
• ORF Size: 1758 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001301012.1, NP_001287941.1
• RefSeq Size: 5393
• RefSeq ORF: 1758
• Locus ID: 2070
• Protein Families: Druggable Genome, Phosphatase, Transcription Factors
• Gene Summary: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (5) has multiple differences in its coding region, compared to variant 1. The resulting isoform (e) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.