Eph receptor B6 (EPHB6) (NM_001280794) Human Untagged Clone

CAT#: SC337322

EPHB6 (untagged) - Human EPH receptor B6 (EPHB6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EPHB6
• Synonyms: HEP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001280794, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTAGCTGTCGGGGGCTGCCGCTGCCAGCCTGGATACCAACCAGCACGAGGAGACAAGGCCTGCCAAG
  CCTGCCCACGGGGGCTCTATAAGGCTTCTGCTGGGAATGCTCCCTGCTCACCATGCCCTGCCCGCAGTCA
  CGCTCCCAACCCAGCAGCCCCCGTTTGCCCCTGCCTGGAGGGCTTCTACCGGGCCAGTTCCGACCCACCA
  GAGGCCCCCTGCACTGGTCCTCCATCGGCTCCCCAGGAGCTTTGGTTTGAGGTGCAAGGCTCAGCACTCA
  TGCTACACTGGCGCCTGCCTCGGGAGCTGGGGGGTCGAGGGGACCTGCTCTTCAATGTCGTGTGCAAGGA
  GTGTGAAGGCCGCCAGGAACCTGCCAGCGGTGGTGGGGGCACTTGTCACCGCTGCAGGGATGAGGTCCAC
  TTCGACCCTCGCCAGAGAGGCCTGACTGAGAGCCGAGTGTTAGTGGGGGGACTCCGGGCACACGTACCCT
  ACATCTTAGAGGTGCAGGCTGTTAATGGGGTGTCTGAGCTCAGCCCTGACCCTCCTCAGGCTGCAGCCAT
  CAATGTCAGCACCAGCCATGAAGTGCCCTCTGCTGTCCCTGTGGTGCACCAGGTGAGCCGGGCATCCAAC
  AGCATCACGGTGTCCTGGCCGCAGCCCGACCAGACCAATGGGAACATCCTGGACTATCAGCTCCGCTACT
  ATGACCAGGCAGAAGACGAATCCCACTCCTTCACCCTGACCAGCGAGACCAACACTGCCACCGTGACACA
  GCTGAGCCCTGGCCACATCTATGGTTTCCAGGTGCGGGCCCGGACTGCTGCCGGCCACGGCCCCTACGGG
  GGCAAAGTCTATTTCCAGACACTTCCTCAAGGGGAGCTGTCTTCCCAGCTTCCAGAAAGACTCTCCTTGG
  TGATCGGCTCCATCCTGGGGGCTTTGGCCTTCCTCCTGCTGGCAGCCATCACCGTGCTGGCGGTCGTCTT
  CCAGCGGAAGCGGCGTGGGACTGGCTACACAGAGCAGCTGCAGCAATACAGCAGCCCAGGACTCGGGGTG
  AAGTATTACATCGACCCCTCCACCTACGAGGACCCCTGTCAGGCCATCCGAGAACTTGCCCGGGAAGTCG
  ATCCTGCTTATATCAAGATTGAGGAGGTCATTGGGACAGGCTCTTTTGGAGAAGTGCGCCAGGGCCGCCT
  GCAGCCACGGGGACGGAGGGAGCAGACTGTGGCCATCCAGGCCCTGTGGGCCGGGGGCGCCGAAAGCCTG
  CAGATGACCTTCCTGGGCCGGGCCGCAGTGCTGGGTCAGTTCCAGCACCCCAACATCCTGCGGCTGGAGG
  GCGTGGTCACCAAGAGCCGACCCCTCATGGTGCTGACGGAGTTCATGGAGCTTGGCCCCCTGGACAGCTT
  CCTCAGGCAGCGGGAGGGCCAGTTCAGCAGCCTGCAGCTGGTGGCCATGCAGCGGGGAGTGGCTGCTGCC
  ATGCAGTACCTGTCCAGCTTTGCCTTCGTCCATCGCTCGCTGTCTGCCCACAGCGTGCTGGTGAATAGCC
  ACTTGGTGTGCAAGGTGGCCCGTCTTGGCCACAGTCCTCAGGGCCCAAGTTGTTTGCTTCGCTGGGCAGC
  CCCAGAGGTCATTGCACATGGAAAGCATACAACATCCAGTGATGTCTGGAGCTTTGGGATACTCATGTGG
  GAAGTGATGAGTTATGGAGAACGGCCTTACTGGGACATGAGTGAGCAGGAGGTACTAAATGCAATAGAGC
  AGGAGTTCCGGCTGCCCCCGCCTCCAGGCTGTCCTCCTGGATTACATCTACTTATGTTGGACACTTGGCA
  GAAGGACCGTGCCCGGCGGCCTCATTTTGACCAGCTGGTGGCTGCATTTGACAAGATGATCCGCAAGCCA
  GATACCCTGCAGGCTGGCGGGGACCCAGGGGAAAGGCCTTCCCAGGCCCTTCTGACCCCTGTGGCCCTGG
  ACTTTCCTTGTCTGGACTCACCCCAGGCCTGGCTTTCAGCCATTGGACTGGAGTGCTACCAGGACAACTT
  CTCCAAGTTTGGCCTCTGTACCTTCAGTGATGTGGCTCAGCTCAGCCTAGAAGACCTGCCTGCCCTGGGC
  ATCACCCTGGCTGGCCACCAGAAGAAGCTGCTGCACCACATCCAGCTCCTTCAGCAACACCTGAGGCAGC
  AGGGCTCAGTGGAGGTCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001280794
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001280794.2, NP_001267723.2
• RefSeq Size: 4008 bp
• RefSeq ORF: 2190 bp
• Locus ID: 2051
• Cytogenetics: 7q34
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance
• Gene Summary: 'This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]'
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks an exon in the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Both variants 2 and 3 encode the same isoform (b).