LONP2 (NM_001300948) Human Untagged Clone

CAT#: SC337500

LONP2 (untagged) - Human lon peptidase 2, peroxisomal (LONP2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LONP2
• Synonyms: LONP; LONPL; PLON; PSLON
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001300948, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCATCAGTGAGCCCCATCCAGATCCCCAGTCGCCTCCCGCTGCTGCTCACCCACGAGGGCGTCCTGC
  TGCCCGGCTCCACCATGCGCACCAGCGTGGACTCGGCCCGCAACCTGCAGCTGGTGCGGAGCCGCCTTCT
  GAAGGGCACGTCGCTGCAAAGCACCATCCTGGGCGTCATCCCCAACACGCCTGACCCCGCCAGCGACGCG
  CAGGACCTGCCGCCGCTGCACAGGATTGGCACAGCTGCACTGGCCGTTCAGGTTGTGGGCAGTAACTGGC
  CCAAGCCCCACTACACTCTGTTGATTACAGGCCTATGCCGTTTCCAGATTGTACAGGTCTTAAAAGAGAA
  GCCATATCCCATTGCTGAAGTGGAGCAGTTGGACCGACTTGAGGAGTTTCCCAACACCTGTAAAATGAGG
  GAGGAGCTAGGAGAACTATCAGAGCAGTTTTACAAATATGCAGTACAAATTTTAGATGCTGTGAGCCTAG
  AGGAGCGGTTCAAGATGACTATACCACTGCTTGTCAGACAAATTGAAGGCCTGAAATTGCTTCAAAAAAC
  CAGAAAACCCAAGCAAGATGATGATAAGAGGGTTATAGCAATACGCCCTATTAGGAGAATTACACATATC
  TCAGGTACTTTAGAAGATGAAGATGAAGATGAAGATAATGATGACATTGTCATGCTAGAGAAAAAAATAC
  GAACATCTAGTATGCCAGAGCAGGCCCATAAAGTCTGTGTCAAAGAGATAAAGAGACTCAAAAAAATGCC
  TCAGTCAATGCCAGAATATGCTCTGACTAGAAATTATTTGGAACTTATGGTAGAACTTCCTTGGAACAAA
  AGTACAACTGACCGCCTGGACATTAGGGCAGCCCGGATTCTTCTGGATAATGACCATTACGCCATGGAAA
  AATTGAAGAAAAGAGTACTGGAATACTTGGCTGTCAGACAGCTCAAAAATAACCTGAAGGGCCCAATCCT
  ATGCTTTGTTGGCCCTCCTGGAGTTGGTAAAACAAGTGTGGGAAGATCAGTGGCCAAGACTCTAGGTCGA
  GAGTTCCACAGGATTGCACTTGGAGGAGTATGTGATCAGTCTGACATTCGAGGACACAGGCGCACCTATG
  TTGGCAGCATGCCTGGTCGCATCATCAACGGCTTGAAGACTGTGGGAGTGAACAACCCAGTGTTCCTATT
  AGATGAGGTTGACAAACTGGGAAAAAGTCTACAGGGTGATCCAGCAGCAGCTCTGCTTGAGGTGTTGGAT
  CCTGAACAAAACCATAACTTCACAGATCATTATCTAAATGTGGCCTTTGACCTTTCTCAAGTTCTTTTTA
  TAGCTACTGCCAACACCACTGCTACCATTCCAGCTGCCTTGTTGGACAGAATGGAGATCATTCAGGTTCC
  AGGTTATACACAGGAGGAGAAGATAGAGATTGCCCATAGGCACTTGATCCCCAAGCAGCTGGAACAACAT
  GGGCTGACTCCACAGCAGATTCAGATACCCCAGGTCACCACTCTTGACATCATCACCAGGTATACCAGAG
  AGGCAGGGGTTCGTTCTCTGGATAGAAAACTTGGGGCCATTTGCCGAGCTGTGGCCGTGAAGGTGGCAGA
  AGGACAGCATAAGGAAGCCAAGTTGGACCGTTCTGATGTGACTGAGAGAGAAGGTTGCAGAGAACACATC
  TTAGAAGATGAAAAACCTGAATCTATCAGTGACACTACTGACTTGGCTCTACCACCTGAAATGCCGATTT
  TGATTGATTTCCATGCTCTGAAAGACATCCTTGGGCCCCCGATGTATGAAATGGAGGTATCTCAGCGTTT
  GAGTCAGCCAGGAGTAGCAATAGGTTTGGCTTGGACTCCCTTAGGTGGAGAAATCATGTTCGTGGAGGCG
  AGTCGAATGGATGGCGAGGGCCAGTTAACTCTGACCGGCCAGCTCGGGGACGTGATGAAGGAGTCCGCCC
  ACCTCGCTATCAGCTGGCTCCGCAGCAACGCAAAGAAGTACCAGCTGACCAATGCTTTTGGAAGTTTTGA
  TCTTCTTGACAACACAGACATCCATCTGCACTTCCCAGCTGGAGCTGTCACAAAAGATGGACCATCTGCT
  GGAGTTACCATAGTAACCTGTCTCGCCTCACTTTTTAGTGGGCGGCTGGTACGTTCAGATGTAGCCATGA
  CTGGAGAAATTACACTGAGAGGTCTTGTTCTTCCAGTGGGTGGAATTAAAGACAAAGTGCTGGCGGCACA
  CAGAGCGGGACTGAAGCAAGTCATTATTCCTCGGAGAAATGAAAAAGACCTTGAGGGAATCCCAGGCAAC
  GTACGACAGGATTTAAGTTTTGTCACAGCAAGCTGCCTGGATGAGGTTCTTAATGCAGCTTTTGATGGTG
  GCTTTACTGTCAAGACCAGACCTGGTCTGTTAAATAGCAAACTGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001300948
• ORF Size: 2427 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001300948.1, NP_001287877.1
• RefSeq Size: 4826
• RefSeq ORF: 2427
• Locus ID: 83752
• Protein Families: Druggable Genome, Protease
• Gene Summary: In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall peroxisome homeostasis as well as proteolytically degrading peroxisomal proteins damaged by oxidation. The protein has an N-terminal Lon N substrate recognition domain, an ATPase domain, a proteolytic domain, and, in some isoforms, a C-terminal peroxisome targeting sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.