SEC31A (NM_001300744) Human Untagged Clone

CAT#: SC337825

SEC31A (untagged) - Human SEC31 homolog A (S. cerevisiae) (SEC31A), transcript variant 7

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SEC31A
• Synonyms: ABP125; ABP130; HSPC275; HSPC334; SEC31L1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001300744, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACC
  TAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGA
  ATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTCACAGGTACCAC
  AAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTG
  AAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCA
  GAATGACAAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCT
  GGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAACCCCAATGACACCAGGAGCCA
  AAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCATCAGC
  CAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCAT
  AGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCG
  AGGATGACCGGTTACCAGTGATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGA
  AAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCTGTGGA
  AAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACAC
  AGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCG
  TATCAGTGTTTATTCTATCATGGGAGGAAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCA
  TCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGA
  CTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTC
  TTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAG
  CAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACC
  AACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTGATGCTTCTCAGAC
  TGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTGGAAAATACCTT
  GAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGCACATTAAAGAGGAAAAAGAAGAATCTGAAT
  TTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGC
  TTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATT
  ATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAA
  GCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCT
  TAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGT
  GATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATA
  TTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTC
  ACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACT
  AGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTA
  TTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACT
  TTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTC
  CCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATC
  CCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCA
  GCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCGTCCTCAGAAT
  GGTTGGAATGACCCTCCAGCTTTGAACAGAGTACCCAAAAAGAAGAAGATGCCTGAAAACTTCATGCCTC
  CTGTTCCCATCACATCACCAATCATGAACCCGTTGGGTGACCCCCAGTCACAAATGCTGCAGCAACAGCC
  TTCAGCTCCAGTACCACTGTCAAGCCAGTCTTCATTCCCACAGCCACATCTTCCAGGTGGCCAGCCCTTC
  CATGGCGTACAGCAACCTCTTGGTCAAACAGGCATGCCACCATCTTTTTCAAAGCCCAATATTGAAGGTG
  CCCCAGGGGCTCCTATTGGAAATACCTTCCAGCATGTGCAGTCTTTGCCAACAAAAAAAATTACCAAGAA
  ACCTATTCCAGATGAGCACCTCATTCTAAAGACCACATTTGAGGATCTTATTCAGCGCTGCCTTTCTTCA
  GCAACAGACCCTCAAACCAAGAGGAAGCTAGATGATGCCAGCAAACGTTTGGAGTTTCTGTATGATAAAC
  TTAGGGAACAGACACTTTCACCAACAATCACCAGTGGTTTACACAACATTGCAAGGAGCATTGAAACTCG
  AAACTACTCAGAAGGATTGACCATGCATACCCACATAGTTAGCACCAGCAACTTCAGTGAGACCTCTGCT
  TTCATGCCAGTTCTCAAAGTTGTTCTCACCCAGGCCAATAAGCTGGGTGTCTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001300744
• ORF Size: 3204 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001300744.2, NP_001287673.1
• RefSeq Size: 3997
• RefSeq ORF: 3204
• Locus ID: 22872
• Gene Summary: The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
  Transcript Variant: This variant (7) lacks two consecutive alternate in-frame exons in the central coding region and an alternate in-frame exon in the 3' coding region, compared to variant 5. The encoded isoform (6) has the same N- and C-termini, but is shorter and has an alternate internal amino acid compared to isoform 1.