CNGB1 (NM_001286130) Human Untagged Clone

CAT#: SC337968

CNGB1 (untagged) - Human cyclic nucleotide gated channel beta 1 (CNGB1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CNGB1
• Synonyms: CNCG2; CNCG3L; CNCG4; CNG4; CNGB1B; GAR1; GARP; GARP2; RCNC2; RCNCb; RCNCbeta; RP45
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001286130, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTGGGCTGGGTCCAGAGGGTGCTGCCTCAGCCCCCAGGGACCCCTCGGAAGACCAAGATGCAGGAGG
  AAGAGGAAGTGGAACCAGAGCCAGAGATGGAGGCGGAGGTGGAACCAGAACCGAATCCTGAGGAGGCCGA
  GACAGAGTCCGAGTCCATGCCCCCCGAAGAGTCATTCAAGGAGGAGGAAGTGGCTGTGGCAGACCCAAGC
  CCTCAGGAGACCAAGGAGGCTGCCCTTACTTCCACCATATCCCTCCGGGCCCAGGGCGCTGAGATTTCTG
  AAATGAATAGTCCCAGCCGCAGGGTACTGACCTGGCTCATGAAGGGCGTAGAGAAGGTGATCCCGCAGCC
  TGTTCACAGCATCACGGAGGACCCGGCTCAGATCCTGGGGCATGGCAGCACTGGGGACACAGGGTGCACA
  GATGAACCCAATGAGGCCCTTGAGGCCCAAGACACTAGGCCTGGGCTGCGGCTGCTTCTGTGGCTGGAGC
  AGAATCTGGAAAGAGTGCTTCCTCAGCCCCCCAAATCCTCTGAGGTCTGGAGAGATGAGCCTGCAGTTGC
  TACAGCGCCTCCAGGACGCCCCCAGGAAATGGGGCCCAAGCTGCAGGCCCGGGAGACCCCCTCCCTGCCC
  ACACCCATCCCCCTGCAGCCCAAGGAGGAACCCAAGGAGGCACCAGCTCCAGAGCCCCAGCCCGGCTCCC
  AGGCCCAGACCTCCTCCCTGCCACCAACCAGGGACCCTGCCAGGCTGGTGGCATGGGTCCTGCACAGGCT
  GGAGATGGCCTTGCCGCAGCCAGTGCTACATGGGAAAATAGGGGAACAGGAGCCTGACTCCCCTGGGATA
  TGTGATGTGCAGACCATCAGCATCCTTCCTGGAGGACAAGTGGAGCCTGACCTTGTCCTAGAGGAGGTTG
  AACCGCCCTGGGAGGATGCCCACCAGGATGTCAGTACCAGCCCACAGGGTACAGAGGTGGTTCCAGCTTA
  TGAAGAAGAGAACAAAGCTGTGGAGAAGATGCCCAGAGAGCTGTCCCGGATTGAAGAGGAGAAAGAAGAT
  GAGGAGGAGGAAGAGGAAGAGGAGGAGGAGGAGGAAGAGGAGGAGGTGACTGAGGTGCTGCTGGATAGCT
  GTGTGGTGTCGCAGGTGGGCGTGGGCCAGAGTGAAGAAGACGGGACCCGGCCCCAGAGCACTTCAGATCA
  GAAGCTGTGGGAGGAAGTTGGGGAGGAGGCCAAGAAGGAGGCTGAAGAGAAGGCCAAGGAGGAGGCCGAG
  GAGGTGGCTGAAGAGGAGGCTGAAAAGGAGCCCCAGGACTGGGCGGAGACCAAGGAGGAGCCTGAGGCTG
  AGGCCGAGGCTGCCAGTTCAGGAGTGCCTGCCACGAAACAGCACCCAGAAGTGCAGGTGGAAGATACTGA
  TGCTGATAGCTGCCCCCTCATGGCAGAAGAGAATCCACCCTCAACCGTGTTGCCGCCACCGTCTCCTGCC
  AAATCAGACACCCTTATAGTCCCAAGCTCAGCCTCGGGGACACACAGGAAGAAGCTGCCCTCTGAGGATG
  ATGAGGCTGAAGAGCTCAAGGCGTTGTCACCAGCAGAGTCCCCAGTGGTTGCCTGGTCTGACCCCACCAC
  CCCGAAGGACACTGATGGCCAGGACCGTGCGGCCTCCACGGCCAGCACAAATAGCGCCATCATCAACGAC
  CGGCTCCAGGAGCTGGTGAAGCTCTTCAAGGAGCGGACAGAGAAAGTGAAGGAGAAACTCATTGACCCTG
  ACGTCACCTCTGATGAGGAGAGCCCCAAGCCCTCCCCAGCCAAGAAAGCCCCAGAGCCAGCTCCAGACAC
  AAAGCCCGCTGAAGCCGAGCCAGTGGAAGAGGAGCACTATTGCGACATGCTCTGCTGCAAGTTCAAACAC
  CGCCCCTGGAAGAAGTACCAGTTTCCCCAGAGCATTGACCCGCTGACCAACCTGATGTATGTCCTATGGC
  TGTTCTTCGTGGTGATGGCCTGGAATTGGAACTGTTGGCTGATTCCCGTGCGCTGGGCCTTCCCCTACCA
  GACCCCGGACAACATCCACCACTGGCTGCTGATGGATTACCTATGCGACCTCATCTACTTCCTGGACATC
  ACCGTGTTCCAGACACGCCTGCAGTTTGTCAGAGGCGGGGACATCATTACGGACAAAAAGGACATGCGAA
  ATAACTACCTGAAGTCTCGCCGCTTCAAGATGGACCTGCTCAGCCTCCTGCCCTTGGATTTTCTCTATTT
  GAAAGTCGGTGTGAACCCCCTCCTCCGCCTGCCCCGCTGTTTAAAGTACATGGCCTTCTTCGAGTTTAAC
  AGCCGCCTGGAATCCATCCTCAGCAAAGCCTACGTGTACAGGGTCATCAGGACCACAGCCTACCTTCTCT
  ACAGCCTGCATTTGAATTCCTGTCTTTATTACTGGGCATCGGCCTATCAGGGCCTCGGCTCCACTCACTG
  GGTTTACGATGGCGTGGGAAACAGTTATATTCGCTGTTACTACTTTGCTGTGAAGACCCTCATCACCATC
  GGGGGGCTGCCTGACCCCAAGACACTCTTTGAAATTGTCTTCCAGCTGCTGAATTATTTCACGGGCGTCT
  TTGCTTTCTCTGTGATGATCGGACAGATGAGAGATGTGGTAGGGGCCGCCACCGCCGGACAGACCTACTA
  CCGCAGCTGCATGGACAGCACGGTGAAGTACATGAATTTCTACAAGATCCCCAAGTCCGTGCAGAACCGC
  GTCAAGACCTGGTACGAGTACACCTGGCACTCGCAAGGCATGCTGGATGAGTCAGAGCTGATGGTGCAGC
  TTCCAGACAAGATGCGGCTGGACCTCGCCATCGACGTGAACTACAACATCGTTAGCAAAGTCGCACTCTT
  TCAGGGCTGTGACCGGCAGATGATCTTTGACATGCTGAAGAGGCTTCGCTCTGTTGTCTACCTGCCCAAC
  GACTATGTGTGCAAGAAGGGGGAGATCGGCCGTGAGATGTACATCATCCAGGCAGGGCAAGTGCAGGTCT
  TGGGCGGCCCTGATGGGAAATCTGTGCTGGTGACGCTGAAAGCTGGATCTGTGTTTGGAGAAATAAGCTT
  GCTGGCTGTTGGGGGCGGGAACCGGCGCACGGCCAACGTGGTGGCGCACGGGTTTACCAACCTCTTCATC
  CTGGATAAGAAGGACCTGAATGAGATTTTGGTGCATTATCCTGAGTCTCAGAAGTTACTCCGGAAGAAAG
  CCAGGCGCATGCTGAGAAGCAACAATAAGCCCAAGGAGGAGAAGAGCGTGCTGATCCTTCCACCCCGGGC
  GGGCACCCCAAAGCTCTTCAACGCTGCCCTCGCTATGACAGGAAAGATGGGTGGCAAGGGGGCAAAAGGC
  GGCAAACTTGCTCACCTCCGGGCCCGGCTCAAAGAACTGGCCGCGCTGGAGGCGGCTGCAAAGCAGCAAG
  AGTTGGTGGAACAGGCCAAGAGCTCGCAAGACGTCAAGGGAGAGGAAGGCTCCGCCGCCCCAGACCAGCA
  CACGCACCCAAAGGAGGCCGCCACCGACCCACCCGCGCCCCGGACGCCCCCCGAGCCCCCGGGGTCTCCA
  CCGAGCTCTCCACCGCCTGCCTCCCTTGGGAGGCCGGAGGGAGAGGAGGAGGGGCCGGCCGAGCCCGAAG
  AGCACTCGGTGAGGATCTGCATGAGCCCGGGCCCGGAGCCGGGAGAGCAGATCCTGTCGGTGAAGATGCC
  GGAGGAAAGGGAGGAGAAGGCGGAGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001286130
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001286130.1, NP_001273059.1
• RefSeq Size: 5645 bp
• RefSeq ORF: 3738 bp
• Locus ID: 1258
• Cytogenetics: 16q21
• Protein Families: Druggable Genome, Ion Channels: Cyclic nucleotide gated
• Protein Pathways: Olfactory transduction
• Gene Summary: 'In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]'
  Transcript Variant: This variant (3) uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.