Collagen IV alpha 6 (COL4A6) (NM_001287760) Human Untagged Clone

CAT#: SC338082

COL4A6 (untagged) - Human collagen, type IV, alpha 6 (COL4A6), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: COL4A6
• Synonyms: CXDELq22.3; DELXq22.3; DFNX6
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001287760, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCACCCTGGGTTGTGGCTGCTCCTGGTTACGTTGTGCCTGACCGAGGAACTGGCAGCAGCGGGAGAGA
  AGTCTTATGGAAAGCCATGTGGGGGCCAGGACTGCAGTGGGAGCTGTCAGTGTTTTCCTGAGAAAGGAGC
  GAGAGGACGACCTGGACCAATTGGAATTCAAGGCCCAACAGGTCCTCAAGGATTCACTGGCTCTACTGGT
  TTATCGGGATTGAAAGGAGAAAGGGGTTTCCCAGGCCTTCTGGGACCTTATGGACCAAAAGGAGATAAGG
  GTCCCATGGGAGTTCCTGGCTTTCTTGGCATCAATGGGATTCCGGGCCACCCTGGACAACCAGGCCCCAG
  AGGCCCACCTGGTCTGGATGGCTGTAATGGAACTCAAGGAGCTGTTGGATTTCCAGGCCCTGATGGCTAT
  CCTGGGCTTCTCGGACCACCCGGGCTTCCTGGTCAGAAAGGATCAAAAGGTGACCCTGTCCTTGCTCCAG
  GTAGTTTCAAAGGAATGAAGGGGGATCCTGGGCTGCCTGGACTGGATGGAATCACTGGCCCACAAGGAGC
  ACCCGGATTTCCTGGAGCTGTAGGACCTGCAGGACCACCAGGATTACAAGGTCCTCCAGGGCCTCCTGGT
  CCTCTTGGTCCTGATGGGAATATGGGGCTAGGTTTTCAAGGAGAGAAAGGAGTCAAGGGGGATGTTGGCC
  TCCCTGGCCCAGCAGGACCTCCACCATCTACTGGAGAGCTGGAATTCATGGGATTCCCCAAAGGGAAGAA
  AGGATCCAAGGGTGAACCAGGGCCTAAGGGTTTTCCAGGCATAAGTGGCCCTCCAGGCTTCCCGGGCCTT
  GGAACTACTGGAGAAAAGGGAGAAAAGGGAGAAAAGGGAATCCCTGGTTTGCCAGGACCTAGGGGTCCCA
  TGGGTTCAGAAGGAGTCCAAGGCCCTCCAGGGCAACAGGGCAAGAAAGGGACCCTGGGATTTCCTGGGCT
  TAATGGATTCCAAGGAATTGAGGGTCAAAAGGGTGACATTGGCCTGCCAGGCCCAGATGTTTTCATCGAT
  ATAGATGGTGCTGTGATCTCAGGTAATCCTGGAGATCCTGGTGTACCTGGCCTCCCAGGCCTTAAAGGAG
  ATGAAGGCATCCAAGGCCTACGTGGCCCTTCTGGTGTCCCTGGATTGCCAGCATTATCAGGTGTCCCAGG
  AGCCCTAGGGCCTCAGGGATTTCCAGGGCTGAAGGGGGACCAAGGAAACCCAGGCCGTACCACAATTGGA
  GCAGCTGGCCTCCCTGGCAGAGATGGTTTGCCAGGCCCACCAGGTCCACCAGGCCCACCTAGTCCAGAAT
  TTGAGACTGAAACTCTACACAACAAAGAGTCAGGGTTCCCTGGTCTCCGAGGAGAACAAGGTCCAAAAGG
  AAACCTAGGCCTCAAAGGAATAAAAGGAGACTCAGGTTTCTGTGCTTGTGACGGTGGTGTTCCCAACACT
  GGACCACCCGGGGAACCAGGCCCACCTGGTCCATGGGGTCTCATAGGCCTTCCAGGCCTTAAAGGAGCCA
  GAGGAGATCGAGGCTCTGGGGGTGCACAGGGCCCAGCAGGGGCTCCAGGCTTAGTTGGGCCTCTGGGTCC
  TTCAGGACCCAAAGGAAAGAAGGGGGAACCAATTCTCAGTACAATCCAAGGAATGCCAGGAGATCGGGGT
  GATTCTGGCTCCCAGGGCTTCCGTGGTGTAATAGGAGAACCAGGCAAGGACGGAGTACCAGGTTTACCAG
  GTCTGCCAGGCCTTCCGGGTGATGGTGGACAGGGCTTCCCAGGTGAAAAGGGGTTACCTGGACTTCCTGG
  TGAAAAAGGCCATCCTGGTCCACCTGGCCTCCCAGGAAATGGGTTACCAGGACTTCCTGGACCCCGTGGG
  CTTCCTGGAGATAAAGGCAAGGATGGATTACCGGGACAACAAGGCCTTCCCGGATCTAAGGGAATCACCC
  TGCCCTGTATTATTCCTGGGTCATACGGTCCATCAGGATTTCCAGGCACTCCCGGATTCCCAGGCCCTAA
  AGGGTCTCGAGGCCTCCCTGGGACCCCAGGCCAGCCTGGGTCAAGTGGAAGTAAAGGAGAGCCAGGGAGT
  CCAGGATTGGTTCATCTTCCTGAATTACCAGGATTTCCTGGACCTCGTGGGGAGAAGGGCTTGCCTGGGT
  TTCCTGGGCTCCCTGGAAAAGATGGCTTGCCTGGGATGATTGGCAGTCCAGGCTTACCTGGTTCCAAGGG
  AGCCACTGGTGACATCTTTGGTGCTGAAAATGGTGCTCCGGGGGAACAAGGCCTACAAGGATTAACAGGG
  CACAAAGGATTTCTTGGAGACTCTGGCCTTCCAGGACTCAAGGGTGTGCACGGGAAGCCTGGCTTACTAG
  GCCCCAAAGGTGAGCGGGGCAGCCCTGGGACACCAGGACAGGTGGGACAGCCAGGCACCCCAGGATCTAG
  TGGTCCATATGGCATCAAGGGCAAATCTGGGCTCCCAGGAGCACCAGGCTTCCCAGGCATCTCAGGACAT
  CCTGGAAAGAAAGGAACAAGAGGCAAGAAAGGTCCTCCTGGATCAATTGTAAAGAAAGGGCTGCCAGGGC
  TAAAAGGCCTTCCTGGAAATCCAGGCCTAGTAGGACTGAAAGGAAGCCCAGGCTCTCCAGGGGTCGCTGG
  GTTGCCAGCCCTCTCTGGACCCAAGGGAGAGAAGGGGTCTGTTGGATTCGTAGGTTTTCCAGGAATACCA
  GGTCTGCCTGGTATTCCTGGAACAAGAGGATTAAAAGGAATTCCAGGATCAACTGGAAAAATGGGACCAT
  CTGGACGTGCTGGTACTCCTGGTGAAAAGGGAGACAGAGGCAATCCGGGGCCAGTCGGAATACCTAGTCC
  AAGACGTCCAATGTCAAACCTTTGGCTCAAAGGAGACAAAGGCTCTCAAGGCTCAGCCGGATCCAATGGA
  TTTCCTGGGCCAAGAGGTGACAAAGGAGAGGCTGGTCGACCTGGACCACCAGGCCTACCTGGAGCTCCTG
  GCCTCCCAGGCATTATCAAAGGAGTTAGTGGAAAGCCAGGGCCCCCTGGCTTCATGGGAATCCGGGGCTT
  ACCTGGCCTGAAGGGGTCCTCTGGGATCACAGGTTTCCCAGGAATGCCAGGAGAAAGTGGTTCACAAGGT
  ATCAGAGGGTCGCCTGGACTCCCAGGAGCATCTGGTCTCCCAGGCCTGAAAGGAGACAACGGCCAGACAG
  TTGAAATTTCCGGTAGCCCAGGACCCAAGGGACAGCCTGGCGAATCTGGTTTTAAAGGCACAAAAGGAAG
  AGATGGACTAATAGGCAATATAGGCTTCCCTGGAAACAAAGGTGAAGATGGAAAAGTTGGTGTTTCTGGA
  GATGTTGGCCTTCCTGGAGCTCCAGGATTTCCAGGAGTTGCCGGCATGAGAGGAGAACCAGGACTTCCAG
  GTTCTTCTGGTCACCAAGGGGCAATTGGGCCTCTAGGATCCCCCGGATTAATAGGACCCAAAGGACCTAG
  TATCACCGGTGTGCCTGGGCCTGCTGGTCTCCCTGGACCCAAAGGAGAAAAAGGATATCCAGGAATTGGC
  ATCGGAGCTCCAGGGAAGCCGGGCCTGAGAGGGCAAAAAGGTGATCGAGGTTTCCCAGGTCTCCAGGGCC
  CTGCTGGTCTCCCCGGTGCCCCAGGCATCTCCTTGCCCTCACTCATAGCAGGACAGCCTGGTGACCCCGG
  GCGACCAGGCCTAGATGGAGAACGAGGCCGCCCAGGCCCCGCTGGACCCCCAGGTCCCCCTGGGCCATCC
  TCGAATCAAGGCGACACCGGAGACCCTGGCTTCCCTGGAATTCCTGGACCTAAAGGGCCTAAGGGAGACC
  AAGGAATTCCAGGTTTTTCTGGCCTCCCTGGAGAGCTAGGACTGAAAGGCTCTTCTGGCCTCCAAGGTGA
  TCCTGGACAAACACCAACTGCAGAAGCTGTCCAGGTTCCTCCTGGACCCTTGGGTCTACCAGGGATCGAT
  GGCATCCCTGGCCTCACTGGGGACCCTGGGGCTCAAGGCCCTGTAGGCCTACAAGGCTCCAAAGGTTTAC
  CTGGCATCCCCGGTAAAGATGGCCCCAGTGGGCTCCCAGGCCCACCTGGGGCTCTTGGTGATCCTGGTCT
  GCCTGGACTGCAAGGCCCTCCAGGATTTGAAGGAGCTCCAGGGCAGCAAGGCCCCTTCGGGATGCCTGGA
  ATGCCTGGCCAGAGCATGAGAGTGGGCTACACGTTGGTAAAGCACAGCCAGTCGGAACAGGTGCCCCCGT
  GTCCCATCGGGATGAGCCAGCTGTGGGTGGGGTACAGCTTACTGTTTGTGGAGGGGCAAGAGAAAGCCCA
  CAACCAGGACCTGGGCTTTGCTGGCTCCTGTCTGCCCCGCTTCAGCACCATGCCCTTCATCTACTGCAAC
  ATCAACGAGGTGTGCCACTATGCCAGGCGCAATGATAAATCTTACTGGCTCTCCACTACCGCCCCTATCC
  CCATGATGCCCGTCAGCCAGACCCAGATTCCCCAGTACATCAGCCGCTGCTCTGTGTGTGAGGCACCCTC
  GCAAGCCATTGCTGTGCACAGCCAGGACATCACCATCCCGCAGTGCCCCCTGGGCTGGCGCAGCCTCTGG
  ATTGGGTACTCTTTCCTCATGCACACTGCCGCTGGTGCCGAGGGTGGAGGCCAGTCCCTGGTCTCACCTG
  GCTCCTGCCTAGAGGACTTTCGGGCCACTCCTTTCATCGAATGCAGTGGTGCCCGAGGCACCTGCCACTA
  CTTTGCAAACAAGTACAGTTTCTGGTTGACCACAGTGGAGGAGAGGCAGCAGTTTGGGGAGTTGCCTGTG
  TCTGAAACGCTGAAAGCTGGGCAGCTCCACACTCGAGTCAGTCGCTGCCAGGTGTGTATGAAAAGCCTGT
  AG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001287760
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001287760.1, NP_001274689.1
• RefSeq Size: 6552 bp
• RefSeq ORF: 4902 bp
• Locus ID: 1288
• Cytogenetics: Xq22.3
• Protein Pathways: ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer
• Gene Summary: 'This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]'
  Transcript Variant: This variant (5) lacks several alternate in-frame exons compared to variant 3. The resulting protein (isoform 5) is shorter compared to isoform 3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.