Hif1a (NM_010431) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR210895L1V

Lenti ORF particles, Hif1a (Myc-DDK-tagged) - Mouse hypoxia inducible factor 1, alpha subunit (Hif1a), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Hif1a
• Synonyms: AA959795; bHLHe78; HIF-1-alpha; HIF1-alpha; HIF1alpha; MOP1
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_010431
• ORF Size: 2508 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR210895).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010431.1, NP_034561.1
• RefSeq Size: 3973
• RefSeq ORF: 2511
• Locus ID: 15251
• Gene Summary: This gene encodes the alpha subunit which, along with the beta subunit, forms a heterodimeric transcription factor that regulates the cellular and developmental response to reduced oxygen tension. The transcription factor has been shown to regulate genes involved in several biological processes, including erythropoiesis and angiogenesis which aid in increased delivery of oxygen to hypoxic regions. The transcription factor also plays a role in the induction of genes involved in cell proliferation and survival, energy metabolism, apoptosis, and glucose and iron metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]