Adam22 (NM_001007221) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR222779L4V
- LentiORF®
Lenti ORF particles, Adam22 (GFP-tagged) - Mouse a disintegrin and metallopeptidase domain 22 (Adam22), transcript variant 2, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Adam22 |
Synonyms | 2900022I03Rik; AI854032; MDC2 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001007221 |
ORF Size | 2463 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR222779).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001007221.2, NP_001007222.1 |
RefSeq Size | 2629 bp |
RefSeq ORF | 2466 bp |
Locus ID | 11496 |
Cytogenetics | 5 3.39 cM |
Gene Summary | This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. The protein encoded by this gene is believed to lack metalloproteinase activity due to the lack of a critical catalytic motif. Mice lacking the encoded protein exhibit severe ataxia, hypomyelination and premature death. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. [provided by RefSeq, May 2016] |
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