Gaa (NM_008064) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR226319L4V
- LentiORF®
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Lenti ORF particles, Gaa (GFP-tagged) - Mouse glucosidase, alpha, acid (Gaa), transcript variant 1, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Gaa |
Synonyms | E430018M07Rik |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_008064 |
ORF Size | 2859 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR226319).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_008064.3, NP_032090.3 |
RefSeq Size | 3756 |
RefSeq ORF | 2862 |
Locus ID | 14387 |
Gene Summary | This gene encodes a lysosomal acid glucosidase that is involved in the degradation of glycogen. The encoded preproprotein undergoes proteolytic processing to generate a mature enzyme that cleaves alpha-1-4 and alpha-1-6 glycosidic bonds of glycogen, maltose and intermediate oligosaccharides within the lysosome. Mice lacking the encoded protein exhibit symptoms similar to human Pompe syndrome such as accumulation of glycogen in cardiac and skeletal muscle lysosomes resulting in reduced mobility and strength. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2015] |
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