Adrenomedullin (ADM) (NM_001124) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200507L3V

Lenti ORF particles, ADM (Myc-DDK tagged) - Human adrenomedullin (ADM), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ADM
• Synonyms: AM; PAMP
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001124
• ORF Size: 555 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200507).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001124.1, NP_001115.1
• RefSeq Size: 1606 bp
• RefSeq ORF: 558 bp
• Locus ID: 133
• Cytogenetics: 11p15.4
• Domains: Adrenomedullin
• Protein Families: Druggable Genome, Secreted Protein
• MW: 20.4 kDa
• Gene Summary: 'The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration. [provided by RefSeq, Aug 2014]'