M6PR (NM_002355) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC201277L4V
- LentiORF®
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Lenti ORF particles, M6PR (mGFP-tagged) - Human mannose-6-phosphate receptor (cation dependent) (M6PR), transcript variant 1, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | M6PR |
Synonyms | CD-M6PR; CD-MPR; MPR-46; MPR 46; MPR46; SMPR |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_002355 |
ORF Size | 831 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC201277).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002355.2, NP_002346.1 |
RefSeq Size | 2583 bp |
RefSeq ORF | 834 bp |
Locus ID | 4074 |
Cytogenetics | 12p13.31 |
Domains | Man-6-P_recep |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Lysosome |
MW | 31 kDa |
Gene Summary | 'This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]' |
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