RAD18 (NM_020165) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201700L1V

Lenti ORF particles, RAD18 (Myc-DDK tagged) - Human RAD18 homolog (S. cerevisiae) (RAD18), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: RAD18
• Synonyms: RNF73
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_020165
• ORF Size: 1485 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201700).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020165.2, NP_064550.2
• RefSeq Size: 5739
• RefSeq ORF: 1488
• Locus ID: 56852
• Domains: RING, SAP, ZnF_Rad18
• Protein Families: Druggable Genome
• MW: 56.2 kDa
• Gene Summary: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008]